Fabrication and Characterization of Self-Assembled Tissue Rings using Patient Cells with Variants in Aneurysm Genes

Aortic Abdominal Aneurysm (AAA) is a chronic degenerative disease of the arterial wall. The aortic vessel wall abnormally dilates due to multiple possible causes and may eventually rupture. It is characterized by several factors leading to the extreme dilation due to the degeneration of the vessel wall extracellular matrix (ECM). It is often...

Turbulence in Aneurysms: Numerical Investigation in Abdominal Aortic Aneurysms

An aneurysm refers to the local dilation or ballooning of a blood vessel and if left unchecked, almost every aneurysm continues to grow in size until it eventually ruptures. The abdominal aorta is the most common location for an aneurysm to form and an abdominal aortic aneurysm (AAA) can turn lethal in the event of rupture. Since the current...

CFD Modeling of Abdominal Aortic Aneurysms

An abdominal aortic aneurysm (AAA) is an excessive localized swelling of the abdominal aortic wall. AAAs are often lethal when they rupture and constitute a significant health risk in the developed countries. CFD simulations can help predict formation, progression, and rupture of AAAs by the use of hemodynamic parameters such as the Oscillatory...