Hardware acceleration of short-read mapping with the Burrows-Wheeler Aligner

Over the last decade, the costs of sequencing a human DNA molecule have been drastically reduced. It is therefore expected that the DNA sequence of patients will be used more often as a diagnostics tool in future clinical applications. However, DNA sequencers deliver millions of small fragments from random positions of the very large DNA string....

Midas v1.0: Multimodal Interface for DNA Alignment of Sequences

Major research efforts in Bioinformatics include sequence alignment, gene finding, genome assembly, protein structure alignment, protein structure prediction, prediction of gene expression and protein-protein interactions, and the modeling of evolution. To perform these specific tasks different tools are used. Using these tools separately is a...