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Henssen, Anne (author)With growing concern over our reliance on non-renewable resources and the environmental impact of conventional manufacturing, the quest for sustainable materials and production processes has intensified. This pursuit has extended to the field of additive manufacturing, where bio-materials have emerged as promising alternatives, aiming to reduce...master thesis 2023
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Putra, N.E. (author)The treatment of large bone injuries continues to be challenging partially due to the limited quantity and quality of bone-replacing materials. Iron (Fe) and its alloys have been developed as a group of load-bearing biomaterials. Recent advances in additive manufacturing (AM) have enhanced the potential of Fe-based biomaterials as biodegradable...doctoral thesis 2023
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de Bruin, Daphne (author)The built environment contributes in a large extend to the global greenhouse gas emissions. With a growing demand for new buildings another view on building products is required. This thesis focusses on creating a biobased sound absorbing panel made from a mycelium bound biomaterial derived from urban waste. The production method for this panel...master thesis 2023
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Zhou, Liangbin (author), Xu, J. (author), Schwab, Andrea (author), Tong, Wenxue (author), Zheng, Lizhen (author), Li, Zhuo (author), Xu, Shunxiang (author), van Osch, G.J.V.M. (author), Wen, Chunyi (author), Qin, Ling (author)As a highly specialized shock-absorbing connective tissue, articular cartilage (AC) has very limited self-repair capacity after traumatic injuries, posing a heavy socioeconomic burden. Common clinical therapies for small- to medium-size focal AC defects are well-developed endogenous repair and cell-based strategies, including microfracture,...review 2023
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Li, Yageng (author), Shi, Yixuan (author), Lu, Yuchen (author), Li, Xuan (author), Zhou, J. (author), Zadpoor, A.A. (author), Wang, Luning (author)With the advancement of additive manufacturing (AM), customized vascular stents can now be fabricated to fit the curvatures and sizes of a narrowed or blocked blood vessel, thereby reducing the possibility of thrombosis and restenosis. More importantly, AM enables the design and fabrication of complex and functional stent unit cells that...review 2023
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Cecotto, Leonardo (author), Stapels, Daphne A.C. (author), van Kessel, Kok P.M. (author), Croes, Michiel (author), Lourens, Zeldali (author), Vogely, H. Charles (author), van der Wal, Bart C.H. (author), van Strijp, Jos A.G. (author), Weinans, H.H. (author), Amin Yavari, Saber (author)Background: Despite the extensive use of silver ions or nanoparticles in research related to preventing implant-associated infections (IAI), their use in clinical practice has been debated. This is because the strong antibacterial properties of silver are counterbalanced by adverse effects on host cells. One of the reasons for this may be the...journal article 2023
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Jiang, Bojing (author), Tan, Sin Yen (author), Fang, Shiyu (author), Feng, Xiaohan (author), Park, B.P. (author), Fok, Hong Kiu Francis (author), Yang, Zhongguang (author), Wang, Ri (author), Kou, Songzi (author), Wu, Angela Ruohao (author), Sun, Fei (author)Spider silk is recognized for its exceptional mechanical properties and biocompatibility, making it a versatile platform for developing functional materials. In this study, a modular functionalization strategy for recombinant spider silk is presented using SpyTag/SpyCatcher chemistry, a prototype of genetically encoded click chemistry. The...journal article 2023
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Yarali, E. (author), Zadpoor, A.A. (author), Staufer, U. (author), Accardo, A. (author), Mirzaali, Mohammad J. (author)Mechanical and morphological design parameters, such as stiffness or porosity, play important roles in creating orthopedic implants and bone substitutes. However, we have only a limited understanding of how the microarchitecture of porous scaffolds contributes to bone regeneration. Meta-biomaterials are increasingly used to precisely engineer...review 2023
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Putra, N.E. (author), Zhou, J. (author), Zadpoor, A.A. (author)The need for sustainable development has never been more urgent, as the world continues to struggle with environmental challenges, such as climate change, pollution, and dwindling natural resources. The use of renewable and recycled waste materials as a source of raw materials for biomaterials and tissue engineering is a promising avenue for...review 2023
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Forman, Jack (author), Pataranutaporn, Pat (author), Gough, Phillip (author), Kim, Raphael (author), Bell, Fiona (author), Ofer, Netta (author), Lu, Jasmine (author), Vujic, Angela (author), Bai, Muqing (author)As knowledge around bio-digital interaction continues to unfold, there are new opportunities for HCI researchers to integrate biology as a design and computational material. Our motivation for the workshop is to bring together interdisciplinary researchers with interest in exploring the next generation of biological HCI and exploring novel...conference paper 2023
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van Hengel, I.A.J. (author)Millions of people around the globe receive orthopedic implants every year. These implants help people to regain their mobility and contribute tremendously to improve the quality of life. However, a significant number of patients suffer from complications, such as implant associated infections (IAI) and aseptic loosening. The number of...doctoral thesis 2022
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Fokker, Marike (author)Bone defects are a common problem in healthcare today. When the damage is too extensive, the human body is not able to heal itself. Different solutions are available, but they all have limitations. Therefore, the search for a solution to overcome these limitations is important. In this theses a way to create a scaffold out of seperate crumpled...master thesis 2022
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Nouri Goushki, M. (author)Osteoimmunomodulation (OIM) is a mechanism through which orthopedic biomaterials may modulate the function of immune cells to promote osteogenesis. OIM is considered a potentially effective way for improving osseointegration. The surface characteristics of orthopedic implants (e.g., topography, wettability, surface chemistry, and charge) can...doctoral thesis 2022
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Kolken, H.M.A. (author)Since the beginning of time, humans have been trying to replace the skeletal system in cases of trauma or disease. Medical devices were designed, manufactured, and implanted, to restore the function of the skeletal system. Fast forward to today and joint replacements are among the most common surgeries carried out in the world. Despite their...doctoral thesis 2022
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Kolken, H.M.A. (author), Garcia, A. Fontecha (author), Plessis, A. Du (author), Meynen, A. (author), Rans, C.D. (author), Scheys, L. (author), Mirzaali Mazandarani, M. (author), Zadpoor, A.A. (author)The fatigue performance of additively manufactured auxetic meta-biomaterials made from commercially pure titanium has been studied only recently. While certain assumptions have been made regarding the mechanisms underlying their fatigue failure, the exact mechanisms are not researched yet. Here, we studied the mechanisms of crack formation...journal article 2022
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Mirzaali, Mohammad J. (author), Moosabeiki Dehabadi, V. (author), Rajaai, S.M. (author), Zhou, J. (author), Zadpoor, A.A. (author)Additive manufacturing (AM, also known as 3D printing) is an advanced manufacturing technique that has enabled progress in the design and fabrication of customised or patient-specific (meta-)biomaterials and biomedical devices (e.g., implants, prosthetics, and orthotics) with complex internal microstructures and tuneable properties. In the past...review 2022
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Ganjian, M. (author), Janbaz, S. (author), van Manen, T. (author), Tümer, N. (author), Modaresifar, K. (author), Minneboo, M.B. (author), Fratila-Apachitei, E.L. (author), Zadpoor, A.A. (author)We designed and fabricated a simple setup for the controlled crumpling of nanopatterned, surface-porous flat metallic sheets for the fabrication of volume-porous biomaterials and showed that crumpling can be considered as an efficient alternative to origami-inspired folding. Before crumpling, laser cutting was used to introduce pores to the...journal article 2022
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van Manen, T. (author), Ganjian, M. (author), Modaresifar, K. (author), Fratila-Apachitei, E.L. (author), Zadpoor, A.A. (author)Folding nanopatterned flat sheets into complex 3D structures enables the fabrication of meta-biomaterials that combine a rationally designed 3D architecture with nanoscale surface features. Self-folding is an attractive approach for realizing such materials. However, self-folded lattices are generally too compliant as there is an inherent...journal article 2022
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Kolken, H.M.A. (author), Callens, S.J.P. (author), Leeflang, M.A. (author), Mirzaali, Mohammad J. (author), Zadpoor, A.A. (author)The rational design of bone-substituting biomaterials is relatively complex because they should meet a long list of requirements for optimal performance. Meta-biomaterials are micro-architected materials that hold great promise for meeting those requirements as they offer a unique combination of mechanical, mass-transport, and biological...journal article 2022
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Kim, Nam Kyeun (author), Lin, Richard (author), Bhattacharyya, Debes (author), van Loosdrecht, Mark C.M. (author), Lin, Y. (author)Eco-friendly flame retardants are greatly required to meet the expectations of low-toxicity, environmental compatibility and sustainability. Extracellular polymeric substances (EPS), the biopolymers recovered from excess granular wastewater sludge, have been successfully incorporated into poly(vinyl alcohol) (PVA) by a solution casting method...journal article 2022