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Blöbaum, Luisa (author), Haringa, C. (author), Grünberger, Alexander (author)Bioprocesses are scaled up for the production of large product quantities. With larger fermenter volumes, mixing becomes increasingly inefficient and environmental gradients get more prominent than in smaller scales. Environmental gradients have an impact on the microorganism's metabolism, which makes the prediction of large-scale performance...review 2023
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Winkelhorst, O.M. (author), Cabau Peinado, O. (author), Straathof, Adrie J.J. (author), Jourdin, L. (author)Microbial electrochemical technologies (METs) employ microorganisms utilizing solid-state electrodes as either electron sink or electron source, such as in microbial electrosynthesis (MES). METs reaction rate is traditionally normalized to the electrode dimensions or to the electrolyte volume, but should also be normalized to biomass amount...journal article 2023
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Ek, Sovannmonica (author)Pulp and paper industries are water-intensive industries and composed of complex production processes. Untreated pulping wastewater is very toxic and lethal to aquatic life if discharged untreated. Anaerobic treatment technology has gained interest in treating these types of wastewater by reducing organic compounds. This thesis research aimed to...master thesis 2022
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Zha, Qinying (author)Palm oil is a popular ingredient in domestic products. The palm oil industry has been growing rapidly over the past decades, so that the amount of palm oil mill effluent (POME) generated from the palm oil production has been increasing as well. The anaerobic membrane bioreactor (AnMBR) is a treatment solution that can remove organic pollutants...student report 2022
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Odriozola, Magela (author)Anaerobic membrane bioreactor (AnMBR) technology is increasingly researched for wastewater treatment in a circular economy scenario to recover nutrients, water, and biogas. AnMBR couples the advantages of anaerobic digestion, such as low sludge production, no aeration requirement and biogas production, with the benefits of membrane technology,...doctoral thesis 2022
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Lip, K.Y.F. (author)Saccharomyces yeasts are common workhorses for the production of alcoholic beverage and bio-ethanol. In these production processes, temperature is one of the predominant factors determining the operational costs of the industrial fermentation processes and the quality of the products (alcoholic beverage) because it influences the functioning of...doctoral thesis 2022
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Odriozola, Magela (author), van Lier, J.B. (author), Spanjers, H. (author)Flux enhancers (FEs) have been successfully applied for fouling mitigation in membrane bioreactors. However, more research is needed to compare and optimise different dosing strategies to improve the filtration performance, while minimising the use of FEs and preventing overdosing. Therefore, the goal of this research is to develop an...journal article 2022
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Szabo Corbacho, M. (author), Pacheco-Ruiz, Santiago (author), Míguez, Diana (author), Hooijmans, Christine Maria (author), Brdjanovic, Damir (author), Garcia, Hector A. (author), van Lier, J.B. (author)This study evaluated the effects of sludge retention time (SRT) on the membrane filtration performance of an anaerobic membrane bioreactor (AnMBR) fed lipid-rich synthetic dairy wastewater. The membrane filtration performance was evaluated in two AnMBR systems operated at two different SRTs, i.e., 20 and 40 days. For the AnMBR operated at 40...journal article 2022
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Holohan, B. Conall (author), Duarte, M. Salomé (author), Szabo Corbacho, M. (author), Cavaleiro, Ana J. (author), Salvador, Andreia F. (author), Pereira, M. Alcina (author), Ziels, Ryan M. (author), Frijters, Carla T.M.J. (author), van Lier, J.B. (author)Several problems associated with the presence of lipids in wastewater treatment plants are usually overcome by removing them ahead of the biological treatment. However, because of their high energy content, waste lipids are interesting yet challenging pollutants in anaerobic wastewater treatment and codigestion processes. The maximal amount...review 2022
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Puiman, L. (author), Abrahamson, Britt (author), van der Lans, R.G.J.M. (author), Haringa, C. (author), Noorman, H.J. (author), Picioreanu, C. (author)Mass transfer limitations in syngas fermentation processes are mostly attributed to poor solubility of CO and H<sub>2</sub> in water. Despite these assumed limitations, a syngas fermentation process has recently been commercialized. Using large-sale external-loop gas-lift reactors (EL-GLR), CO-rich off-gases are converted into ethanol, with...journal article 2022
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Gallego Murillo, Joan Sebastián (author), Iacono, Giulia (author), van der Wielen, L.A.M. (author), van den Akker, Emile (author), von Lindern, Marieke (author), Wahl, S.A. (author)Transfusion of donor-derived red blood cells (RBCs) is the most common form of cell therapy. Production of transfusion-ready cultured RBCs (cRBCs) is a promising replacement for the current, fully donor-dependent therapy. A single transfusion unit, however, contains 2 × 10<sup>12</sup> RBC, which requires large scale production. Here, we...journal article 2022
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Mustafa Abdelrahman, Amr (author), Furkan Aras, Muhammed (author), Cicekalan, Busra (author), Fakioglu, Malhun (author), Cingoz, Seyma (author), Basa, Safak (author), Ozgun, Hale (author), Ozturk, Izzet (author), van Lier, J.B. (author)Energy-rich sludge can be obtained from primary clarifiers preceding biological reactors. Alternatively, the incoming wastewater can be sent to a very-high-loaded activated sludge system, i.e., a so-called A-stage. However, the effects of applying an A-stage instead of a primary clarifier, on the subsequent sludge digestion for long-term...journal article 2022
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Minden, Steven (author), Aniolek, Maria (author), Sarkizi Shams Hajian, Christopher (author), Teleki, Attila (author), Zerrer, Tobias (author), Delvigne, Frank (author), van Gulik, W.M. (author), Deshmukh, Amit (author), Noorman, H.J. (author), Takors, Ralf (author)Carbon limitation is a common feeding strategy in bioprocesses to enable an efficient microbiological conversion of a substrate to a product. However, industrial settings inherently promote mixing insufficiencies, creating zones of famine conditions. Cells frequently traveling through such regions repeatedly experience substrate shortages and...journal article 2022
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de Hulster, A.F. (author), Mooiman, C. (author), Timmermans, Rowin (author), Mans, R. (author)Evolutionary engineering of microbes provides a powerful tool for untargeted optimization of (engineered) cell factories and identification of genetic targets for further research. Directed evolution is an intrinsically time-intensive effort, and automated methods can significantly reduce manual labor. Here, design considerations for various...journal article 2022
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Song, Ji Won (author), Baeg, Yoonjin (author), Jeong, Ha Yeon (author), Lee, Jinwon (author), Oh, Deok Kun (author), Hollmann, F. (author), Park, Jin Byung (author)Bacterial outer membrane vesicles (OMVs) are small unilamellar proteoliposomes, involved in various functions including cell-to-cell signalling and protein excretion. We have engineered the OMVs of Escherichia coli to nano-scaled bioreactors for the biotransformation of fatty acids by targeting a fatty acid double bond hydratase of...journal article 2021
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Perdigão Elisiário, M. (author), De Wever, Heleen (author), Van Hecke, Wouter (author), Noorman, H.J. (author), Straathof, Adrie J.J. (author)Syngas fermentation to biofuels and chemicals is an emerging technology in the biobased economy. Mass transfer is usually limiting the syngas fermentation rate, due to the low aqueous solubilities of the gaseous substrates. Membrane bioreactors, as efficient gas–liquid contactors, are a promising configuration for overcoming this gas-to...review 2021
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Odriozola, Magela (author), Lousada Ferreira, M. (author), Spanjers, H. (author), van Lier, J.B. (author)Fouling is a major challenge for the economic feasibility and applicability of membrane bioreactors. Several strategies have been proposed for fouling control, and among them, addition of flux enhancers (FE) have shown promising results. Previous research revealed a high variability of the required optimal dosage of FE for different types of...journal article 2021
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Talaei, Maryam (author), Mahdavinejad, Mohammadjavad (author), Azari, Rahman (author), Prieto Hoces, A.I. (author), Sangin, Hamed (author)As a state-of-the-art green façade technology, building-integrated microalgae bioreactor has the potential to reduce buildings’ carbon footprint and energy consumption. The present study aims to address the knowledge gap in the energy and daylighting performance of algae photobioreactor façade. The paper first studies the effects of algae...journal article 2021
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Kim, E. (author), Ćurko, Josip (author), Gajdoš Kljusurić, Jasenka (author), Matošić, Marin (author), Crnek, Vlado (author), López-Vázquez, Carlos M. (author), Garcia, H. (author), Brdjanovic, Damir (author), Valinger, Davor (author)The use of near-infrared (NIR) spectroscopy in wastewater treatment has continuously expanded. As an alternative to conventional analytical methods for monitoring constituents in wastewater treatment processes, the use of NIR spectroscopy is considered to be cost-effective and less time-consuming. NIR spectroscopy does not distort the...journal article 2021
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Peschard Navarrete, Rogelio (author)Fouling is the main limitation to the application of membrane bioreactors (MBRs). Understanding the complexity of fouling has led to better decision making for design and operation of MBRs. However, studies have shown contradictory results of the impact of sludge characteristics on membrane filtration performance and fouling propensity. The...master thesis 2020