Machine learning algorithm to estimate cardiac output based on non-invasive arterial blood pressure measurements

Cardiac output (CO), a vital hemodynamic parameter that reflects the blood volume pumped by the heart per minute, is crucial for determining tissue oxygen delivery and the heart's ability to meet the body's demands. Researchers have developed various methods to measure cardiac output, including thermodilution using pulmonary artery catheters ...

Closed-loop model of the blood pressure regulation system during postural changes: Modelling to better understand the underlying mechanisms of Orthostatic Hypotension (OH)

Background and aims: Orthostatic hypotension (OH) is a common manifestation of abnormal blood pressure (BP) regulation. The relative contribution and interaction of the physiological systems that alter or maintain adequate BP is largely unknown. Developing a closed-loop model is necessary to investigate the complex physiological function and...

Soliton Interpretation of Arterial Blood Pressure Waveform: Derivation, Verification of Korteweg-de Vries type Dynamics and Application of Nonlinear Fourier Analysis

As a nonlinear alternative to the linear interpretation of arterial blood pressure waveform, soliton theory has been proposed to model arterial blood pressure by interpreting the pulsatile nature of pressure pulses in the viewpoint of soliton transmission. The existing solitary wave literature supports this interpretation by deriving Korteweg-de...

Design of a Care Pathway for Preventive Blood Pressure Monitoring: Qualitative Study

Background: Electronic health (eHealth) services could provide a solution for monitoring the blood pressure of at-risk patients while also decreasing expensive doctor visits. However, a major barrier to their implementation is the lack of integration into organizations.<br/><br/>Objective: Our aim was to design a Care Pathway for monitoring the...

Blood pressure change does not associate with Center of Pressure movement after postural transition in geriatric outpatients

Background: Orthostatic hypotension (OH), a blood pressure drop after postural change, is associated with impaired standing balance and falls in older adults. This study aimed to assess the association between blood pressure (BP) and a measure of quality of standing balance, i.e. Center of Pressure (CoP) movement, after postural change from...

Standing up slowly antagonises initial blood pressure decrease in older adults with orthostatic hypotension

Background: Orthostatic hypotension (OH) is common in older adults and associated with increased morbidity and mortality, loss of independence and high health-care costs. Standing up slowly is a recommended non-pharmacological intervention. However, the effectiveness of this advice has not been well studied. Objectives: The aim of this study...