Searched for: subject%3A%22Cell%255C+BE%22
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Godino, E. (author), Danelon, C.J.A. (author)
Mimicking bacterial cell division in well-defined cell-free systems has the potential to elucidate the minimal set of proteins required for cytoskeletal formation, membrane constriction, and final abscission. Membrane-anchored FtsZ polymers are often regarded as a sufficient system to realize this chain of events. By using purified FtsZ and...
journal article 2023
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Sakata, Dousatsu (author), Hirayama, Ryoichi (author), Shin, Wook Geun (author), Belli, Mauro (author), Tabocchini, Maria A. (author), Stewart, Robert D. (author), Brown, J.M.C. (author), Kyriakou, G.I. (author), Tran, Hoang N. (author)
Purpose: Track structure Monte Carlo (MC) codes have achieved successful outcomes in the quantitative investigation of radiation-induced initial DNA damage. The aim of the present study is to extend a Geant4-DNA radiobiological application by incorporating a feature allowing for the prediction of DNA rejoining kinetics and corresponding cell...
journal article 2023
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van Veldhuizen, B.N. (author), van Biert, L. (author), Amladi, A. (author), Woudstra, T. (author), Visser, K. (author), Aravind, P.V. (author)
An increasing demand in the marine industry to reduce emissions led to investigations into more efficient power conversion using fuels with sustainable production pathways. Solid Oxide Fuel Cells (SOFCs) are under consideration for long-range shipping, because of its high efficiency, low pollutant emissions, and fuel flexibility. SOFC systems...
journal article 2023
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Zhang, Yuxuan (author), Zhai, Xiaoqiang (author), Zhang, Fengyuan (author), Zhang, Zhongbin (author), Hooman, K. (author), Zhang, Hai (author), Wang, Xiaolin (author)
Enhancing gas-liquid mass transfer is key to promote gas hydrate formation kinetics. Encapsulation of CO<sub>2</sub> hydrate is expected to dramatically increase gas-liquid contact to enhance mass transfer. However, gas hydrate encapsulation has never been proposed as the technical issues of gas permeation through capsule shells have never...
journal article 2023
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Blanch Jover, A. (author), Dekker, C. (author)
The Cdv system is the protein machinery that performs cell division and other membrane-deforming processes in a subset of archaea. Evolutionarily, the system is closely related to the eukaryotic ESCRT machinery, with which it shares many structural and functional similarities. Since its first description 15 years ago, the understanding of the...
review 2023
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van der Sluis, Tetje C. (author), Beyrend, Guillaume (author), van der Gracht, Esmé T.I. (author), Abdelaal, T.R.M. (author), Jochems, Simon P. (author), Belderbos, Robert A. (author), Wesselink, Thomas H. (author), van Duikeren, Suzanne (author), Arens, Ramon (author)
Immune checkpoint therapy (ICT) has the power to eradicate cancer, but the mechanisms that determine effective therapy-induced immune responses are not fully understood. Here, using high-dimensional single-cell profiling, we interrogate whether the landscape of T cell states in the peripheral blood predict responses to combinatorial targeting...
journal article 2023
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Liu, H. (author), Nadar, R.A. (author), Fauzia, R.P. (author), Laan, A.C. (author), Wang, R. (author), van Cooten, Quenteijn (author), Carroll, E.C.M. (author), Eelkema, R. (author), Denkova, A.G. (author)
Combination of therapies is a common strategy in cancer treatment. Such combined therapies only have merit provided that there is superior therapeutic outcome with fewer side effects, compared to single therapies. Here, this work explores the possibility to combine chemotherapy with radionuclide therapy using polymeric micelles as a delivery...
journal article 2023
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Sharaf, A.M.S.E. (author), Frimat, J. P. (author), Kremers, G. J. (author), Accardo, A. (author)
Two-photon polymerization (2PP) has provided the field of cell biology with the opportunity to fabricate precisely designed microscaffolds for a wide range of studies, from mechanobiology to in vitro disease modelling. However, a multitude of commercial and in-house developed photosensitive materials employed in 2PP suffers from high auto...
journal article 2023
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Zhou, Liangbin (author), Xu, J. (author), Schwab, Andrea (author), Tong, Wenxue (author), Zheng, Lizhen (author), Li, Zhuo (author), Xu, Shunxiang (author), van Osch, G.J.V.M. (author), Wen, Chunyi (author), Qin, Ling (author)
As a highly specialized shock-absorbing connective tissue, articular cartilage (AC) has very limited self-repair capacity after traumatic injuries, posing a heavy socioeconomic burden. Common clinical therapies for small- to medium-size focal AC defects are well-developed endogenous repair and cell-based strategies, including microfracture,...
review 2023
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Cordes, Martijn (author), Pike-Overzet, K. (author), van den Akker, E.B. (author), Staal, F.J.T. (author), Canté-Barrett, Kirsten (author)
Traditionally, flow cytometry has been the preferred method to characterize immune cells at the single-cell level. Flow cytometry is used in immunology mostly to measure the expression of identifying markers on the cell surface, but—with good antibodies—can also be used to assess the expression of intracellular proteins. The advent of single...
review 2023
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da Silva, Renan F. (author), Hansen, Jeff E. (author), Lowe, Ryan J. (author), Rijnsdorp, D.P. (author), Buckley, Mark L. (author)
Nearshore rocky reefs with scales of order 10–100 m are common along the world's coastline and often shape wave-driven hydrodynamics and shoreline morphology in their lee. The interaction of waves with these reefs generally results in either two or four-cell mean circulation systems (2CC and 4CC, respectively), with diverging flows behind the...
journal article 2023
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Ji, Encheng (author), Leijsten, Lieke (author), Witte-Bouma, Janneke (author), Rouchon, Adelin (author), Di Maggio, Nunzia (author), Banfi, Andrea (author), van Osch, G.J.V.M. (author), Farrell, Eric (author), Lolli, Andrea (author)
Tissue engineering bone via endochondral ossification requires the generation of a cartilage template which undergoes vascularisation and remodelling. While this is a promising route for bone repair, achieving effective cartilage vascularisation remains a challenge. Here, we investigated how mineralisation of tissue-engineered cartilage...
journal article 2023
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Yang, Sora (author), Klughammer, N. (author), Barth, A. (author), Tanenbaum, M. (author), Dekker, C. (author)
Single-molecule fluorescence imaging experiments generally require sub-nanomolar protein concentrations to isolate single protein molecules, which makes such experiments challenging in live cells due to high intracellular protein concentrations. Here, we show that single-molecule observations can be achieved in live cells through a drastic...
journal article 2023
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Geelhoed, Jeanine S. (author), Thorup, Casper A. (author), Bjerg, Jesper J. (author), Schreiber, Lars (author), Nielsen, Lars Peter (author), Schramm, Andreas (author), Meysman, F.J.R. (author), Marshall, Ian P.G. (author)
Bacterial cells can vary greatly in size, from a few hundred nanometers to hundreds of micrometers in diameter. Filamentous cable bacteria also display substantial size differences, with filament diameters ranging from 0.4 to 8 µm. We analyzed the genomes of cable bacterium filaments from 11 coastal environments of which the resulting 23 new...
journal article 2023
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Akolawala, Q. (author), Keuning, F.E. (author), Rovituso, M. (author), van Burik, Wouter (author), van der Wal, E.M. (author), Versteeg, Henri H. (author), Rondon, Araci M.R. (author), Accardo, A. (author)
Glioblastoma (GBM) is a devastating cancer of the brain with an extremely poor prognosis. While X-ray radiotherapy and chemotherapy remain the current standard, proton beam therapy is an appealing alternative as protons can damage cancer cells while sparing the surrounding healthy tissue. However, the effects of protons on in vitro GBM models...
journal article 2023
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Henzel, J. (author), Bakker, N.J. (author), Najafi, Mehrdad (author), Zardetto, Valerio (author), Veenstra, Sjoerd (author), Isabella, O. (author), Mazzarella, L. (author), Weeber, A.W. (author), Theelen, Mirjam (author)
Nonequal current generation in the cells of a photovoltaic module, e.g., due to partial shading, leads to operation in reverse bias. This quickly causes a significant efficiency loss in perovskite solar cells. We report a more quantitative investigation of the reverse bias degradation. Various small reverse biases (negative voltages) were...
journal article 2023
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Husseini, Abbas Ali (author), Yazdani, Ali Mohammad (author), Ghadiri, Fatemeh (author), Sisman, A.S. (author)
We developed a microchip device using surface acoustic waves (SAW) and sharp-edge glass microparticles to rapidly lyse low-level cell samples. This microchip features a 13-finger pair interdigital transducer (IDT) with a 30-degree focused angle, creating high-intensity acoustic beams converging 6 mm away at a 16 MHz frequency. Cell lysis is...
journal article 2023
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Wehrens, Martijn (author), Krah, Laurens H.J. (author), Towbin, Benjamin D. (author), Hermsen, Rutger (author), Tans, S.J. (author)
The inherent stochasticity of metabolism raises a critical question for understanding homeostasis: are cellular processes regulated in response to internal fluctuations? Here, we show that, in E. coli cells under constant external conditions, catabolic enzyme expression continuously responds to metabolic fluctuations. The underlying...
journal article 2023
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Polat, S. (author), Kortlever, R. (author), Eral, H.B. (author)
Electrochemical carbon dioxide (CO<sub>2</sub>) reduction is a promising route to convert intermittent renewable energy into fuels and valuable chemical products. Separation of CO<sub>2</sub> reduction products by ion-selective electrochemical technology may play a decisive role in the pursuit of commercially viable CO<sub>2</sub> reduction...
journal article 2023
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Velot, Émilie (author), Balmayor, Elizabeth R. (author), Bertoni, Lélia (author), Chubinskaya, Susan (author), Cicuttini, Flavia (author), de Girolamo, Laura (author), Demoor, Magali (author), van Osch, G.J.V.M. (author), Cucchiarini, Magali (author)
review 2023
Searched for: subject%3A%22Cell%255C+BE%22
(41 - 60 of 565)

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