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Novella-Rausell, Claudio (author), Grudniewska, Magda (author), Peters, Dorien J.M. (author), Mahfouz, A.M.E.T.A. (author)The kidney's cellular diversity is on par with its physiological intricacy; yet identifying cell populations and their markers remains challenging. Here, we created a comprehensive atlas of the healthy adult mouse kidney (MKA: Mouse Kidney Atlas) by integrating 140.000 cells and nuclei from 59 publicly available single-cell and single-nuclei...journal article 2023
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Zhou, Y. (author), Ibrahim, Aya (author), Muttillo, M. (author), Manganiello, P. (author), Ziar, H. (author), Isabella, O. (author)This paper presents the fundamental study on the relationship between LED light sources and the performance of solar cell as receivers in visible light communication (VLC) links. Here, different colors of LEDs are modulated with a sinusoidal signal, and the bandwidth of the VLC system based on various c-Si PV architectures is characterized at...conference paper 2023
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Van de Cauter, L. (author), van Buren, L. (author), Koenderink, G.H. (author), Ganzinger, Kristina A. (author)Creating an artificial cell from the bottom up is a long-standing challenge and, while significant progress has been made, the full realization of this goal remains elusive. Arguably, one of the biggest hurdles that researchers are facing now is the assembly of different modules of cell function inside a single container. Giant unilamellar...review 2023
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Fang, P. (author), Li, Xiao (author), Jiang, X. (author), Hopman, J.J. (author), Bai, Yong (author)Predicting the bending behaviours of a submarine power cable (SPC) is always a tough task due to its complex geometry and inner layer contact, not to mention the stick–slip mechanism. A full-scale finite element model is cumbersome during the early design stage and a more efficient model for practical use is required. Therefore, in this paper...journal article 2023
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Kingma, E. (author), Diepeveen, E.T. (author), Iñigo de la Cruz, L.M. (author), Laan, L. (author)The ability of cells to translate different extracellular cues into different intracellular responses is vital for their survival in unpredictable environments. In Saccharomyces cerevisiae, cell polarity is modulated in response to environmental signals which allows cells to adopt varying morphologies in different external conditions. The...journal article 2023
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Polat, S. (author), Kortlever, R. (author), Eral, H.B. (author)Selective ion separation is a fundamental challenge with applications ranging from the manufacturing of pharmaceuticals & industrial salts to water desalination. In particular, the separation of formate, a primary product of electrochemical carbon dioxide reduction, has attracted attention not only to reduce carbon emissions and energy...journal article 2023
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Kapetanović, M. (author), Nunez, Alfredo (author), van Oort, N. (author), Goverde, R.M.P. (author)Hydrogen fuel cell multiple unit vehicles are acquiring a central role in the transition process towards carbon neutral trains operation in non-electrified regional railway networks. In addition to their primary role as a transport mean, these vehicles offer significant potential for applications in innovative concepts such as smart grids....journal article 2023
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van Veldhuizen, B.N. (author), Zera, E. (author), van Biert, L. (author), Modena, S. (author), Visser, K. (author), Aravind, P.V. (author)Solid Oxide Fuel Cell (SOFC) systems have the potential to reduce emissions from seagoing vessels. However, it is unknown whether ship motions influence the system's operation. In this research, a 1.5 kW SOFC module is operated on an inclination platform that emulates ship motions, to evaluate the influence of static and dynamic inclinations...journal article 2023
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Schwab, Andrea (author), Wesdorp, Marinus A. (author), Xu, J. (author), Abinzano, Florencia (author), Loebel, Claudia (author), Levato, Riccardo (author), Eglin, David (author), Narcisi, Roberto (author), Malda, Jos (author), van Osch, G.J.V.M. (author)Background: The use of acellular hydrogels to repair osteochondral defects requires cells to first invade the biomaterial and then to deposit extracellular matrix for tissue regeneration. Due to the diverse physicochemical properties of engineered hydrogels, the specific properties that allow or even improve the behaviour of cells are not yet...journal article 2023
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Peng, Q. (author), Vermolen, F.J. (author), Weihs, D. (author)Cancer cell migration between different body parts is the driving force behind cancer metastasis, which causes mortality of patients. Migration of cancer cells often proceeds by penetration through narrow cavities in possibly stiff tissues. In our previous work [12], a model for the evolution of cell geometry is developed, and in the current...book chapter 2023
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Wehrens, Martijn (author), Krah, Laurens H.J. (author), Towbin, Benjamin D. (author), Hermsen, Rutger (author), Tans, S.J. (author)The inherent stochasticity of metabolism raises a critical question for understanding homeostasis: are cellular processes regulated in response to internal fluctuations? Here, we show that, in E. coli cells under constant external conditions, catabolic enzyme expression continuously responds to metabolic fluctuations. The underlying...journal article 2023
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Trabelsi, Mohamed (author), Makhamreh, Harnza (author), Alquennah, Alamera Nouran (author), Vahedi, H (author)This study proposes the application of a Lyapunov-based Model Predictive Control (L-MPC) approach to a 9-level Crossover Switches Cell (CSC9) converter operating in grid connection mode. The proposed method utilizes the structure of the classical finite-control-set MPC (FCS-MPC) technique while integrating a cost function that requires no tuning...conference paper 2023
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Li, L. (author), Lukszo, Z. (author), Schmitz, J.E.J. (author)Hydrogen is becoming increasingly popular as a clean, secure, and affordable energy source for the future. This study develops an approach for designing a PV–battery–electrolyzer–fuel cell energy system that utilizes hydrogen as a long-term storage medium and battery as a short-term storage medium. The system is designed to supply load demand...journal article 2023
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van Veldhuizen, B.N. (author), van Biert, L. (author), Amladi, A. (author), Woudstra, T. (author), Visser, K. (author), Aravind, P.V. (author)An increasing demand in the marine industry to reduce emissions led to investigations into more efficient power conversion using fuels with sustainable production pathways. Solid Oxide Fuel Cells (SOFCs) are under consideration for long-range shipping, because of its high efficiency, low pollutant emissions, and fuel flexibility. SOFC systems...journal article 2023
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Zhang, Yuxuan (author), Zhai, Xiaoqiang (author), Zhang, Fengyuan (author), Zhang, Zhongbin (author), Hooman, K. (author), Zhang, Hai (author), Wang, Xiaolin (author)Enhancing gas-liquid mass transfer is key to promote gas hydrate formation kinetics. Encapsulation of CO<sub>2</sub> hydrate is expected to dramatically increase gas-liquid contact to enhance mass transfer. However, gas hydrate encapsulation has never been proposed as the technical issues of gas permeation through capsule shells have never...journal article 2023
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Sakata, Dousatsu (author), Hirayama, Ryoichi (author), Shin, Wook Geun (author), Belli, Mauro (author), Tabocchini, Maria A. (author), Stewart, Robert D. (author), Brown, J.M.C. (author), Kyriakou, G.I. (author), Tran, Hoang N. (author)Purpose: Track structure Monte Carlo (MC) codes have achieved successful outcomes in the quantitative investigation of radiation-induced initial DNA damage. The aim of the present study is to extend a Geant4-DNA radiobiological application by incorporating a feature allowing for the prediction of DNA rejoining kinetics and corresponding cell...journal article 2023
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Godino, E. (author), Restrepo Sierra, A.M. (author), Danelon, C.J.A. (author)The reconstitution of basic cellular functions in micrometer-sized liposomes has led to a surge of interest in the construction of synthetic cells. Microscopy and flow cytometry are powerful tools for characterizing biological processes in liposomes with fluorescence readouts. However, applying each method separately leads to a compromise...journal article 2023
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Warmink, Kelly (author), Rios, Jaqueline L. (author), Varderidou-Minasian, Suzy (author), Torres-Torrillas, Marta (author), van Valkengoed, Devin R. (author), Versteeg, Sabine (author), Eijkelkamp, Niels (author), Weinans, Harrie (author), Korthagen, Nicoline M. (author), Lorenowicz, Magdalena J. (author)Background: Mesenchymal stromal/stem cells (MSCs) and MSC-derived extracellular vesicles (MSC-EVs) hold promise as a disease modifying treatment in osteoarthritis (OA). Obesity, and its associated inflammation, contribute to OA development and metabolic OA represents a specific and significant group of the OA patient population. Given their...journal article 2023
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Wu, Huan (author), Luo, Houcai (author), Zhang, Jingping (author), Zheng, Bofeng (author), Lang, Lei (author), Wang, Zeping (author), Zhang, Kouchi (author), Chen, Xianping (author)To investigate the unclamped inductive switch (UIS) characteristics, 1200 V silicon carbide (SiC) planar MOSFETs with four cell topologies of linear, current sharing linear, square, and hexagon are designed and manufactured. The experimental platform was built and tested. The results show that the single pulse avalanche energy density of the...journal article 2023
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van der Sluis, Tetje C. (author), Beyrend, Guillaume (author), van der Gracht, Esmé T.I. (author), Abdelaal, T.R.M. (author), Jochems, Simon P. (author), Belderbos, Robert A. (author), Wesselink, Thomas H. (author), van Duikeren, Suzanne (author), Arens, Ramon (author)Immune checkpoint therapy (ICT) has the power to eradicate cancer, but the mechanisms that determine effective therapy-induced immune responses are not fully understood. Here, using high-dimensional single-cell profiling, we interrogate whether the landscape of T cell states in the peripheral blood predict responses to combinatorial targeting...journal article 2023