Searched for: subject%3A%22Cell%255C%252BBE%22
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Restrepo Sierra, A.M. (author)
Life, the most complex and admirable machine that one could think of has evolved over billions of years to display a beautiful variety of mechanisms that keep cells adapting, selfmaintaining, reproducing, and evolving. If we think about it, what is this magic? What are the mechanisms behind life’s origins and wonderful coordination? Attracted by...
doctoral thesis 2024
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Kok, R.N.U. (author)
How does the small intestine maintain itself? What mechanism does it use to achieve<br/>homeostasis, and how optimal is this mechanism? We approached these questions<br/>mainly using cell tracking in organoids, for which we developed new cell trackers.<br/>We found that the intestinal crypt uses a surprisingly simple and effective strategy.<br/...
doctoral thesis 2024
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Tišma, M. (author)
This thesis explores the mechanisms that underlie chromosome organization in bacteria. Bacteria are considered amongst the simplest living organisms on our planet. They lack the cellular organization found in other domains of life (Archaea or Eukaryotics) and often have simpler life cycles. Over the past decade, we gained increasing knowledge...
doctoral thesis 2024
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Recalde Moreno Del Rocio, M.D.R. (author)
The global market for the wastewater treatment industry has been compelled to devise new concepts due to several factors. Currently, approximately 80% of untreated wastewater is discharged worldwide. The conventional technology for municipal solid waste treatment, which has been in use for over a century, is only partially effective in terms of...
doctoral thesis 2024
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Klughammer, N. (author)
In this thesis, we have introduced palladium zero-mode waveguides (Pd ZMWs) as a valuable tool for biophysics research and have showcased several applications thereof. We started by using them as single-molecule sensors for free translocations of fluorophores, proteins, and voltage-driven translocations of DNA. By studying salt-gradient driven...
doctoral thesis 2023
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Gallego Murillo, Joan Sebastián (author)
Production of cultured red blood cells (cRBCs) hold the promise of being a potentially unlimited source of cells that could cover the increasing demand of RBCs for transfusion purposes, while having more control on the quality and safety of the cells compared to the current donor-dependent system. cRBCs could also be used for novel therapies in...
doctoral thesis 2023
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Kingma, E. (author)
All living systems possess the ability to evolve. This ability has allowed life to adopt a large diversity of shapes, colors, sizes and lifestyles. However, despite being a fundamental property of life, our knowledge of what makes living systems evolvable is limited. The fact that evolution can be sometimes be hopelessly unpredictable while in...
doctoral thesis 2023
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Koster, C.C. (author)
Building synthetic cells is extremely interesting from a fundamental perspective, as the ability to rationally build viable, dividing, and self-maintaining cells provides knowledge on the minimal requirements to sustain life. This should enhance our understanding about which biological parts are minimally required for a cell to live, and how...
doctoral thesis 2023
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Egberts, G. (author)
Burns can make patients’ lives quite miserable. Apart from prominent and thickened, or hypertrophic, scars, the skin may be characterized by contraction. When this contraction is so severe that the patient loses joint mobility, it is called contracture. Then a patient may have difficulties with sports or other daily activities. The consequence...
doctoral thesis 2023
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Chen, N. (author)
The issue of climate change, including global warming, poses a significant challenge to our planet. In response to this challenge, the Paris Agreement was signed, which aims to limit the rise in global temperatures to well below 2 <sup style="--tw-border-spacing-x: 0; --tw-border-spacing-y: 0; --tw-translate-x: 0; --tw-translate-y: 0; --tw...
doctoral thesis 2023
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Weninger, B. (author)
We have to overcome the intermittent nature of renewables to master the energy transition. Harvesting renewable electricity is only part of the solution. Energy storage is another part and the main challenge of our time. Only with efficient storage solutions can big industries switch to renewables.<br/>Electricity storage is most efficient with...
doctoral thesis 2023
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Mourragui, S.M.C. (author)
Extensive efforts in cancer research over the past decades have markedly improved diagnosis and treatments, leading to better outcomes for cancer patients. Paradoxically, however, these discoveries have begun to shed light on a level of complexity that rules out the emergence of a universal cancer treatment. As any tumor is now known to be...
doctoral thesis 2023
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Baldauf, L. (author)
Cells are the fundamental units of life. They make up all living things, from bacteria that live in the soil, to archea that give thermal springs their bright colors, to trees and humans. All of these cells share some common functions: they build themselves from basic building blocks, following the instructions of their genetic blueprint, and...
doctoral thesis 2022
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Blanch Jover, A. (author)
All living organisms share the need to replicate and proliferate to ensure the survival of their species. In prokaryotes, this is generally guaranteed by a process of cell division where a mother cell is split into two equally sized daughter cells, and it is a complex and heterogeneous process across all the different species. When looking into...
doctoral thesis 2022
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van Linden, N. (author)
Ammonia (NH3) is one of world’s most-produced chemicals and is mostly used as a raw resource for fertilisers. From the used NH3-based fertilisers, almost half of the NH3 ends up in receiving water bodies, leading to eutrophication, eventually resulting in species diversity loss in the aquatic environment. To minimise environmental damage, total...
doctoral thesis 2022
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de Wagter, C. (author)
Highly automated Unmanned Aerial Vehicles (UAVs) or "flying robots" are rapidly becoming an important asset to society. The last decade has seen the advent of an impressive number of new UAV types and applications. For many applications, the UAVs need to be safe, highly automated, and versatile. Safety is a prerequisite to allowing their use in...
doctoral thesis 2022
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van Buren, L. (author)
Everything that we consider alive, be it plants, dogs, bacteria or humans, is composed of the same microscopic building blocks: cells. While cells between and even within these organisms can look and behave very differently, they all share the same key functionalities: they can grow, they can divide to proliferate, they can eat and metabolise to...
doctoral thesis 2022
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Han, C. (author)
In the efficiency-driven photovoltaic (PV) industry, the market dominating crystalline silicon (c-Si) technology has been developing towards PV devices with carrier-selective passivating contacts (CSPCs). Especially, the silicon heterojunction (SHJ) solar cell, based on hydrogenated amorphous silicon (a-Si:H) contact stacks, and the poly-Si...
doctoral thesis 2022
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Nouri Goushki, M. (author)
Osteoimmunomodulation (OIM) is a mechanism through which orthopedic biomaterials may modulate the function of immune cells to promote osteogenesis. OIM is considered a potentially effective way for improving osseointegration. The surface characteristics of orthopedic implants (e.g., topography, wettability, surface chemistry, and charge) can...
doctoral thesis 2022
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Godino, E. (author)
The Christophe Danelon lab is involved in the long-term effort to construct an autonomous minimal cell using a bottom-up approach. Our goal is to achieve self-maintenance, selfreproduction, and evolution of a liposome compartment containing a minimal genome and a cell-free gene expression system. Self-reproduction requires splitting of the...
doctoral thesis 2022
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