Searched for: subject%3A%22Cell%255C%252BBE%22
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Michielsen, L.C.M. (author), Reinders, M.J.T. (author), Mahfouz, A.M.E.T.A. (author)
Most regulatory elements, especially enhancer sequences, are cell population-specific. One could even argue that a distinct set of regulatory elements is what defines a cell population. However, discovering which non-coding regions of the DNA are essential in which context, and as a result, which genes are expressed, is a difficult task. Some...
journal article 2024
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Amladi, Amogh (author), Venkataraman, V. (author), Woudstra, T. (author), Aravind, P.V. (author)
Energy storage is vital for the energy transition, enabling reliable power grids based on intermittent renewables. Reversible solid oxide cell (rSOC) technology is promising for seasonal energy storage. The novel finding from this work is that optimised air recirculation for rSOC in endothermic electrolyser mode leads to efficiency being...
journal article 2024
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Azevedo Vasconcelos, A.C. (author), Valiya Valappil, S. (author), Schott, D.L. (author), Jovanova, J. (author), Aragon, A.M. (author)
Underwater noise resulting from the monopile driving process can cause severe damage to marine wildlife, such as hearing injury, behavioral disturbance, or even death. Although current noise-attenuation techniques used in this process have shown a significant noise reduction at high frequency ranges, mitigating low-frequency noise is still...
journal article 2024
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Zhang, Zhenya (author), Mao, Jia (author), Wei, Houyu (author), Cheng, Chuanxiao (author), Liu, Zhengxuan (author)
Proton exchange membrane fuel cells offer promising clean energy solutions for various applications. However, their performance relies heavily on the properties of the microporous layer, which plays a crucial role in transporting and distributing the components in the fuel cell. To date, the potential for optimising the microporous layer...
journal article 2024
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Hoekstra, Mirjam E. (author), Slagter, Maarten (author), Urbanus, Jos (author), Toebes, Mireille (author), Slingerland, Nadine (author), de Rink, Iris (author), Kluin, Roelof J.C. (author), Nieuwland, Marja (author), Wessels, L.F.A. (author)
Cells in the tumor microenvironment (TME) influence each other through secretion and sensing of soluble mediators, such as cytokines and chemokines. While signaling of interferon γ (IFNγ) and tumor necrosis factor α (TNFα) is integral to anti-tumor immune responses, our understanding of the spatiotemporal behavior of these cytokines is...
journal article 2024
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Chrafih, Younes (author), Al-Hattab, Mohamed (author), El Boubekri, A. (author), Rahmani, Khalid (author), Bajjou, Omar (author), Basyooni, Mohamed A. (author)
Tandem solar cells have a wider photon absorption range, allowing them to provide better efficiency than single-junction SC. The upper cell absorbs high-energy photons, while the lower cell absorbs low-energy filtered photons. However, in order to obtain affordable, efficient, and long-lasting SC, the absorber layers of the top and bottom...
journal article 2024
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El Ghazi, Haddou (author), Eker, Yasin Ramazan (author), En-nadir, Redouane (author), Ahmed, Shrouk Eid Zaki (author), Basyooni, Mohamed A. (author)
The paper deals with the conception and feasibility of the device structure based on the optimized PIN-(In, Ga)N homojunction solar cells. A new and efficient model combining the most realistic ones considering the impacts of band gap narrowing, collection efficiency, Shockley-Read-Hall recombination, and interface polarization is proposed to...
journal article 2024
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Kuruganti, V.V. (author), Isabella, O. (author), Mihailetchi, Valentin D. (author)
Interdigitated back contact (IBC) architecture can yield among the highest silicon wafer-based solar cell conversion efficiencies. Since both polarities are realized on the rear side, there is a definite need for a patterning step. Some of the common patterning techniques involve photolithography, inkjet patterning, and laser ablation. This...
journal article 2024
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Balzani, Daniel (author), Heinlein, A. (author), Klawonn, Axel (author), Knepper, Jascha (author), Nurani Ramesh, Sharan (author), Rheinbach, Oliver (author), Saßmannshausen, Lea (author), Uhlmann, Klemens (author)
A computational framework is presented to numerically simulate the effects of antihypertensive drugs, in particular calcium channel blockers, on the mechanical response of arterial walls. A stretch-dependent smooth muscle model by Uhlmann and Balzani is modified to describe the interaction of pharmacological drugs and the inhibition of smooth...
journal article 2024
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Berkhout, J. B. (author), Poormoghadam, D. (author), Yi, C. (author), Kalsbeek, A. (author), Meijer, O. C. (author), Mahfouz, A.M.E.T.A. (author)
The hypothalamic paraventricular nucleus (PVN) is a highly complex brain region that is crucial for homeostatic regulation through neuroendocrine signaling, outflow of the autonomic nervous system, and projections to other brain areas. In the past years, single-cell datasets of the hypothalamus have contributed immensely to the current...
journal article 2024
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Useche, Sergio A. (author), Alonso, Francisco (author), Faus, Mireia (author), Trejo, Arturo Cervantes (author), Castaneda, Isaac (author), Oviedo-Trespalacios, O. (author)
Introduction. Technological advancements have the potential to enhance people’s quality of life, but their misuse can have a detrimental impact on safety. A notable example is the escalating issue of distracted driving resulting from the use of mobile phones behind the wheel, leading to severe crashes and injuries. Despite these concerns,...
journal article 2024
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van den Broek, M.A. (author), Ortiz Merino, R.A. (author), Bennis, N.X. (author), Wronska, A.K. (author), Else-Hassing, J. (author), Daran-Lapujade, P.A.S. (author), Daran, J.G. (author)
The biobased-economy aims to create a circular biotechnology ecosystem to transition from a fossil fuel-based to a sustainable industry based on biomass. For this, new microbial cell-factories are essential. We present the draft genome of the CEN.PK-derived Saccharomyces cerevisiae SpyCas9 expressing strain (IMX2600), that serve as chassis of...
journal article 2024
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Androulakis, Ioannis (author), Ferrero, Riccardo (author), van Oossanen, R. (author), Manzin, Alessandra (author), Denkova, A.G. (author), Djanashvili, K. (author), Nadar, R.A. (author), van Rhoon, G.C. (author)
While hyperthermia has been shown to induce a variety of cytotoxic and sensitizing effects on cancer tissues, the thermal dose–effect relationship is still not well quantified, and it is still unclear how it can be optimally combined with other treatment modalities. Additionally, it is speculated that different methods of applying...
journal article 2023
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Abdelhakim, Ahmed (author), Soeiro, Thiago B. (author), Stecca, M. (author), Canales, Francisco (author)
Compact and efficient power converter solutions are seen to be the backbone of future transportation systems in order to cope with the ongoing transition toward greener systems. Such systems usually comprise a main load section, in which one or more propulsion or traction motors are connected, in addition to an auxiliary load, which might...
journal article 2023
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Wu, Huan (author), Luo, Houcai (author), Zhang, Jingping (author), Zheng, Bofeng (author), Lang, Lei (author), Wang, Zeping (author), Zhang, Kouchi (author), Chen, Xianping (author)
To investigate the unclamped inductive switch (UIS) characteristics, 1200 V silicon carbide (SiC) planar MOSFETs with four cell topologies of linear, current sharing linear, square, and hexagon are designed and manufactured. The experimental platform was built and tested. The results show that the single pulse avalanche energy density of the...
journal article 2023
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Das Sadiq, Kabir (author), Aravind, P.V. (author), Woudstra, T. (author), Jaiganesh, N. (author), Ajith kumar, R. (author)
The performance of a 30-kW gasifier–SOFC–GT system was evaluated using thermodynamic calculations. Nickel/Gadolinia Doped Ceria (Ni/GDC) anodes were utilized for Solid Oxide Fuel Cells (SOFCs). These systems can achieve high electrical efficiencies of above 50%. The goal of the study is to evaluate trends in system efficiency when carbon...
journal article 2023
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Chen, N. (author), Tune, Daniel (author), Buchholz, Florian (author), Roescu, Razvan (author), Zeman, M. (author), Isabella, O. (author), Mihailetchi, Valentin D. (author)
In this study, the edge passivation effectiveness and long-term stability of Nafion polymer in n-type interdigitated back contact (IBC) solar cells are investigated. For new module technologies such as half-cut, triple-cut, or shingled modules, cutting of the cells introduces unpassivated edges with a high recombination rate and this limits the...
journal article 2023
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Garmendia Urdalleta, A. (author), van Poll, M.A. (author), Fahy, Niamh (author), Witte-Bouma, Janneke (author), van Wamel, Willem (author), Apachitei, I. (author), Zadpoor, A.A. (author), Fratila-Apachitei, E.L. (author), Farrell, Eric (author)
Macrophage responses following the implantation of orthopaedic implants are essential for successful implant integration in the body, partly through intimate crosstalk with human marrow stromal cells (hMSCs) in the process of new bone formation. Additive manufacturing (AM) and plasma electrolytic oxidation (PEO) in the presence of silver...
journal article 2023
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Kingma, E. (author), Diepeveen, E.T. (author), Iñigo de la Cruz, L.M. (author), Laan, L. (author)
The ability of cells to translate different extracellular cues into different intracellular responses is vital for their survival in unpredictable environments. In Saccharomyces cerevisiae, cell polarity is modulated in response to environmental signals which allows cells to adopt varying morphologies in different external conditions. The...
journal article 2023
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Kuruganti, V.V. (author), Mazurov, Alexander (author), Seren, Sven (author), Isabella, O. (author), Mihailetchi, Valentin D. (author)
In this work, we developed an in situ annealing process to crystallize boron-doped amorphous silicon [a-Si(p+)] layers deposited by atmospheric pressure chemical vapour deposition (APCVD) to form boron-doped polycrystalline silicon [poly-Si(p+)] layers. The influence of the temperature profiles during a-Si(p+) inline deposition on structural,...
journal article 2023
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