Searched for: subject%3A%22Cell%255C%252BBE%22
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Vermolen, F.J. (author), Gefen, A. (author)
A phenomenological model is formulated to model cellular forces on extracellular material. The model is capable of modelling both expansion and contractile forces. This work is based on the assumption of linear elasticity, which allows a superposition argument to arrive at fundamental expressions for cellular forces. It is also shown how the...
journal article 2015
document
Vermolen, F.J. (author), Van der Meijden, R.P. (author), Van Es, M. (author), Gefen, A. (author), Weihs, D. (author)
A phenomenological model is formulated to model the early stages of tumor formation. The model is based on a cell-based formalism, where each cell is represented as a circle or sphere in two-and three dimensional simulations, respectively. The model takes into account constituent cells, such as epithelial cells, tumor cells, and T-cells that...
journal article 2015
document
Vermolen, F.J. (author), Gefen, A. (author)
A phenomenological model for the evolution of shape transition of cells is considered. These transitions are determined by the emission of growth-factors, as well as mechanical interaction if cells are subjected to hard impingement. The originality of this model necessitates a formal treatment of the mathematical model, as well as the...
journal article 2012
document
Vermolen, F.J. (author), Gefen, A. (author)
We consider the movement and viability of individual cells in cell colonies. Cell movement is assumed to take place as a result of sensing the strain energy density as a mechanical stimulus. The model is based on tracking the displacement and viability of each individual cell in a cell colony. Several applications are shown, such as the dynamics...
journal article 2011
Searched for: subject%3A%22Cell%255C%252BBE%22
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