Development of a microfluidic system for modelling the heart-kidney interaction in vitro: Design guidelines and proof-of-concept

Cardiorenal Syndrome (CRS) is a multi-organ disease characterized by a reciprocal pathological interaction between the heart and kidneys during acute or chronic injury. Yet, a complete understanding of the underlying bi-directional pathophysiological mechanisms is lacking, hence obscuring effective diagnostic strategies, patient stratification...

Connecting Molecular Dynamics and Computational Fluid Dynamics

One of the most important developments in the last centuries is the process of miniaturisation and understanding everything that it entails. For the physical sciences this meant the continuing discovery what matter is and how it behaves, while from a practical point of view it meant that more advanced medical, scientific, and consumer...

A Conjugate Heat Transfer Method Applied to Turbomachinery

A Conjugate Heat Transfer (CHT) analysis allows the calculation of the heat transfer and temperature of a body placed in a fluid. The CHT analysis takes into account both the conduction in the solid and the convection in the fluid. Present paper describes a CHT method that uses two separate solvers: one CFD solver dedicated to the flow...