The Value of Tractography: Towards More Accurate Targeting in Deep Brain Stimulation?

<b>Introduction</b>: Deep brain stimulation (DBS) is an important therapeutic option for various neurological diseases. For certain indications the optimal target cannot be identified on structural magnetic resonance imaging (MRI), but can be visualized with tractography. A recent improvement for clinical practice is the probabilistic...

Prediction of the optimal deep brain stimulation contacts based on local field potentials measured by the implanted neurostimulator in Parkinson’s disease

Introduction: Over the past two decades deep brain stimulation (DBS) has emerged as an important therapeutic option for Parkinson’s disease (PD). However, the current DBS programming method, monopolar review (MPR), is time-consuming, requires highly trained personnel and causes discomfort for patients. This study aimed to predict the optimal...

3-D Target Classification in Short Range Radar Applications

Over the years in the automotive industry, the use of radar sensors in advanced driver assistant systems (ADAS) has been increasing, shining a light on various safety and security concerns to be dealt, that come along with it. The performances of existing sensor technologies such as camera, LIDAR and GPS can be very well complemented by the use...

A 0.96-mW dB-Linear Variable Gain Amplifier With 0.4-dB Linearity Error Over a 62.4-dB Gain Tuning Range

This letter presents a low-power dB-linear variable gain amplifier (VGA) with a small linear-in-dB error over a wide gain tuning range. An exponential current ratio is realized in the linear-in-dB control circuit based on the subthreshold I-V characteristic. The VGA is built with subthreshold common-gate transistors as current steering,...

ECG Artefact Suppression and External Data Synchronization with the Medtronic Percept, a Deep Brain Stimulator with Sensing Technology

Deep brain stimulation (DBS) is used to treat a variety of movement disorders. In current DBS therapy, the stimulation parameters are manually adjusted based on a subjective assessment of patient’s symptoms. State-of-the-art DBS research focuses on recording brain activity to create a patient-specific neuronal profile that correlates with the...

Cavity‐box soi: Advanced silicon substrate with pre‐patterned box for monolithic mems fabrication

Several Silicon on Insulator (SOI) wafer manufacturers are now offering products with customer‐defined cavities etched in the handle wafer, which significantly simplifies the fabrication of MEMS devices such as pressure sensors. This paper presents a novel cavity buried oxide (BOX) SOI substrate (cavity‐BOX) that contains a patterned BOX...

Localization of Autonomous Vehicle using 1D Automotive Radar Sensor: Car localization based on Radar and LIDAR Fusion

The overall purpose of this study is to establish novel methods of vehicle localization and mapping using a 1D linear automotive radar array in conjuncture with pre-existing lidar maps, and to test if the generated radar map can be made to be 3 dimensional. The reason for creating a novel localization method was to try and alleviate some of the...

Studying the nanostructure of a-Si:h solar cell absorber layers using positrion annihilation and neutron reflectometry

Hydrogenated Amorphous Silicon (a-Si:H) is a very promising solar cell material with a good potential to use in many applications, as it is cheap to produce, light-weight and flexible. However, upon prolonged exposure to light, the layers suffer from both metastable and irreversible changes (the Staebler-Wronski effect) that have a bad effect on...

Li-Ion Charger for Implantable Devices - Selection of optimal charge algorithm and implementation

Deep Brain Stimulation (DBS) is a method for treating diseases like Parkinson’s Disease (PD) and various other movement disorders. An Implantable Pulse Generator (IPG) is placed in the chest and wires are run through the neck to provide electrical pulses to a certain target in the brain via an electrode. Results with this treatment are good but...

Kiezen voor duurzame kwaliteit: Hoe een publieke opdrachtgever kan sturen op de realisatie van duurzame kwaliteit voor, tijdens en na het keuzeproces voor een bouworganisatievorm

Two recent developments are the motivation for this research: • Increasing awareness of sustainability and thus the will to design and build with sustainable ambitions. • The emergence of integrated project delivery methods, also because of the changing roles between government and market. Problem statement: When developing a sustainable...

Minder angst bij het geïntegreerde aanbesteden: Handleiding voor opdrachtgevers voor de afstemming van vraag en aanbod bij geïntegreerde aanbestedingstrajecten

De toepassing van geïntegreerde contracten is in opkomst. Ze biedt voordelen, maar de toepassing kent ook nadelen. Voordelen ten opzichte van het traditionele model zijn ondermeer de verhoogde sturing op tijd en geld, maar daar tegenover staat een verminderde sturing op het kwaliteitsaspect. Er is een angstbeeld ontstaan bij voornamelijk kleine...