A Fully Implantable Closed-loop System for Autonomous Opioid Detection and Treatment

With over 75,000 attributed deaths in 2020, opioid overdose is now the leading cause of death amongst Americans under the age of 50. With record-breaking increases in fatalities for the past 10 years, fentanyl in particular has many experts worried about the future of the opioid epidemic. To reverse opioid overdose there exists a drug called...

Injectable pH-responsive Ureido-Pyrimidinone (UPy) hydrogel as drug carrier for epicardial activation

The presence of a stem cell source in the epicardium that can be stimulated by exogenous delivery of transforming growth factor-β (TGF-β) and migrate towards the myocardium can represent a new approach to achieve cardiac repair following myocardial infarction. However, injection of drugs always requires use of carriers which help stabilize the...