Analysis of Diffusion MRI: Disentangling the Entangled Brain

The white matter of the brain contains all the connections between different parts of the grey matter. Many diseases especially affect the brain’s white matter. For instance, the white matter tracts are destroyed in neurodegenerative diseases, such as Alzheimer’s disease. Accordingly, there is a large interest in features of the white matter to...

Quantifying Pathology in Diffusion Weighted MRI

In this thesis algorithms are proposed for quantification of pathology in Diffusion Weighted Magnetic Resonance Imaging (DW-MRI) data. Functional evidence for brain diseases can be explained by specific structural loss in the white matter of the brain. That is, certain biomarkers may exist where the disease inhibits improper functioning. Axonal...