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Copeland, S.M. (author), Hinrichs-Krapels, S. (author), Fecondo, Federica (author), Santizo, Esteban Ralon (author), Bal, Roland (author), Comes, M. (author)BACKGROUND: Prompted by recent shocks and stresses to health systems globally, various studies have emerged on health system resilience. Our aim is to describe how health system resilience is operationalised within empirical studies and previous reviews. We compare these to the core conceptualisations and characteristics of resilience in a...journal article 2023
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Fritz, E.K. (author), Ferreira, Carlos (author), Boorsma, Koen (author)<br/><br/>This article proposes an efficient correction model that enables the extension of the blade element momentum method (BEM) for swept blades. Standard BEM algorithms, assuming a straight blade in the rotor plane, cannot account for the changes in the induction system introduced by blade sweep. The proposed extension corrects the axial...journal article 2022
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Kusnandar, K. (author), van Kooten, O. (author), Brazier, F.M. (author)Participation of local actors has shown to be of significant importance to the uptake of new approaches to agricultural initiatives in developing countries. This paper proposes a new approach to empower local chain actors to work together to understand their own and others’ challenges, to pursue common understanding of their situations and...journal article 2019
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Brickwedde, A. (author), van den Broek, M.A. (author), Geertman, Jan Maarten A. (author), Magalhães, Frederico (author), Kuijpers, Niels G.A. (author), Gibson, Brian (author), Pronk, J.T. (author), Daran, J.G. (author)The lager brewing yeast Saccharomyces pastorianus, an interspecies hybrid of S. eubayanus and S. cerevisiae, ferments maltotriose, maltose, sucrose, glucose and fructose in wort to ethanol and carbon dioxide. Complete and timely conversion ("attenuation") of maltotriose by industrial S. pastorianus strains is a key requirement for process...journal article 2017
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Mirzaali, Mohammad J. (author), Habibi, M. (author), Janbaz, S. (author), Vergani, L. (author), Zadpoor, A.A. (author)Crumpled-based materials are relatively easy to fabricate and show robust mechanical properties for practical applications, including meta-biomaterials design aimed for improved tissue regeneration. For such requests, however, the structure needs to be porous. We introduce a crumpled holey thin sheet as a robust bio-metamaterial and measure...journal article 2017
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Steenhuisen, B.M. (author), De Bruijne, M.L.C. (author)Background Energy network companies are commonly attributed the public task to help society in becoming greener in the domain of energy. This extra public task has high costs and comes with high uncertainties. It may also compete with existing public tasks of network companies. When network companies are involved in local green initiatives, they...journal article 2015
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Krishnan, S.T. (author), Moolman, M.C. (author), Van Laar, T. (author), Meyer, A.S. (author), Dekker, N.H. (author)Background Chromosome engineering encompasses a collection of homologous recombination-based techniques that are employed to modify the genome of a model organism in a controlled fashion. Such techniques are widely used in both fundamental and industrial research to introduce multiple insertions in the same Escherichia coli strain. To date, ?...journal article 2015
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Deibel, E. (author)The introduction of open source in the life sciences is increasingly being suggested as an alternative to patenting. This is an alternative, however, that takes its shape at the intersection of the life sciences and informatics. Numerous examples can be identified wherein open source in the life sciences refers to access, sharing and...journal article 2014
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Van Wijk, A.J.M. (author)A sustainable world can only be achieved by an open collaboration between science, business and the public. That is why we create the Green Village: an innovative, lively, interactive and challenging environment where entrepreneurs, innovators, companies, artists, teachers and visitors can meet, work and play to develop, apply and experience...book 2013
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Gonzalez-Ramos, D. (author), Van den Broek, M. (author), Van Maris, A.J.A. (author), Pronk, J.T. (author), Daran, J.M.G. (author)Background n-Butanol and isobutanol produced from biomass-derived sugars are promising renewable transport fuels and solvents. Saccharomyces cerevisiae has been engineered for butanol production, but its high butanol sensitivity poses an upper limit to product titers that can be reached by further pathway engineering. A better understanding of...journal article 2013
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Koopman, F.W. (author), Beekwilder, J. (author), Crimi, B. (author), Van Houwelingen, A. (author), Hall, R.D. (author), Bosch, D. (author), Van Maris, A.J.A. (author), Pronk, J.T. (author), Daran, J.M. (author)Background Flavonoids comprise a large family of secondary plant metabolic intermediates that exhibit a wide variety of antioxidant and human health-related properties. Plant production of flavonoids is limited by the low productivity and the complexity of the recovered flavonoids. Thus to overcome these limitations, metabolic engineering of...journal article 2012
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Daran, J.M. (author), Pronk, J.T. (author), Driessen, A.J.M. (author), Nijland, J.G. (author), Lamboo, F. (author), Puig-Martinez, M. (author), Veiga, T. (author), Gombert, A.K. (author)Penicillium chrysogenum is widely used as an industrial antibiotic producer, in particular in the synthesis of ß-lactam antibiotics such as penicillins and cephalosporins. In industrial processes, oxalic acid formation leads to reduced product yields. Moreover, precipitation of calcium oxalate complicates product recovery. We observed oxalate...journal article 2011