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Marchiori, S. (author), Scharp, Kevin (author)Recent work on philosophy of technology emphasises the ways in which technology can disrupt our concepts and conceptual schemes. We analyse and challenge existing accounts of conceptual disruption, criticising views according to which conceptual disruption can be understood in terms of uncertainty for conceptual application, as well as views...journal article 2024
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Steeneken, P.G. (author)Motion is all around us, the universe is full of moving matter and this motion is surprisingly predictable. The field of science and engineering that studies time-dependent motion in the presence of forces is called Dynamics. In this book we will introduce the core concepts in dynamics and provide a comprehensive toolset to predict and analyse...book 2024
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van den Broek, M.A. (author), Ortiz Merino, R.A. (author), Bennis, N.X. (author), Wronska, A.K. (author), Else-Hassing, J. (author), Daran-Lapujade, P.A.S. (author), Daran, J.G. (author)The biobased-economy aims to create a circular biotechnology ecosystem to transition from a fossil fuel-based to a sustainable industry based on biomass. For this, new microbial cell-factories are essential. We present the draft genome of the CEN.PK-derived Saccharomyces cerevisiae SpyCas9 expressing strain (IMX2600), that serve as chassis of...journal article 2024
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van Denderen, R. Pepijn (author), Schielen, R.M.J. (author), Paarlberg, Andries J. (author), Reneerkens, Michiel (author), Augustijn, Denie C. M. (author)Local river interventions, such as channel narrowing or side channels, are often necessary to maintain safety, ecology, or navigation. Such interventions have different effects on the river's bed morphology during periods of high- and low-discharge events. Mapping the bed-level variations for different discharge levels and understanding these...journal article 2024
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Ylla Arbos, C. (author), Blom, A. (author), White, S. R. (author), Patzwahl, R. (author), Schielen, R.M.J. (author)Erosion-control measures in rivers aim to provide sufficient navigation width, reduce local erosion, or to protect neighboring communities from flooding. These measures are typically devised to solve a local problem. However, local channel modifications trigger a large-scale channel response in the form of migrating bed level and sediment...journal article 2024
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Ingram, A.A. (author), Oike, K. (author)Astonishing progress has been achieved in unlocking new-to-nature biocatalysis in the past decades. The progress in protein engineering enabled research to efficiently incorporate artificial structural elements into enzyme design. Recent trends include cofactor mimetics, artificial metalloenzymes and non-canonical amino acids. In this...journal article 2024
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van Grunsven, J.B. (author), Franssen, T.M. (author), Gammon, A.R. (author), Marin, L. (author)The guiding premise of this chapter is that we, as teachers in higher education, must consider how the content and form of our teaching can foster inclusivity through a responsiveness to neurodiverse learning styles. A narrow pedagogical focus on lectures, textual engagement, and essay-writing threatens to exclude neurodivergent students whose...book chapter 2024
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Challenges and opportunities for CO2 electroreduction from a process systems engineering perspectiveDal Mas, R. (author), Somoza Tornos, A. (author), Pérez-Fortes, Mar (author), Kortlever, R. (author), Kiss, A.A. (author)Despite the huge efforts devoted to the development of the electrochemical reduction of CO2 (ECO2R) in the past decade, still many challenges are present, hindering further approaches to industrial applications. This paper gives a perspective on these challenges from a Process Systems Engineering (PSE) standpoint, while at the same time...journal article 2024
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Haverkort, J.W. (author)Electrochemical engineering deals with electrochemical devices like electrolysers, fuel cells, and batteries. While several excellent books exist in this long-standing and still growing field, their focus is usually on chemistry or phenomenology. In this textbook, we focus on mathematical modelling of the physical phenomena involved. Instead of...book 2024
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Miedema, Rene (author), Strydis, C. (author)IntroductionIn-silico simulations are a powerful tool in modern neuroscience for enhancing our understanding of complex brain systems at various physiological levels. To model biologically realistic and detailed systems, an ideal simulation platform must possess: (1) high performance and performance scalability, (2) flexibility, and (3) ease of...journal article 2024
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Shomar, Helena (author), Bokinsky, G.E. (author)Reactions catalysed by iron-sulfur (Fe-S) enzymes appear in a variety of biosynthetic pathways that produce valuable natural products. Harnessing these biosynthetic pathways by expression in microbial cell factories grown on an industrial scale would yield enormous economic and environmental benefits. However, Fe-S enzymes often become...review 2024
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Dizani, A. (author), Ghorbani, Amineh (author), Taebi, B. (author), van de Poel, I.R. (author)In recent decades, distinct national approaches to engineering ethics have evolved, each tailored to its unique contextual factors. These contextual disparities make it unfeasible to transfer one country's engineering ethics approach directly into another. This calls for a compelling need to enhance our comprehension of engineering ethics...journal article 2024
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Andersen, Rasmus (author), Napoleone, A. (author), Andersen, Ann Louise (author), Brunoe, Thomas Ditlev (author), Nielsen, Kjeld (author)Pursuing manufacturing competitiveness in the dynamic industrial landscape necessitates implementing changeable and reconfigurable manufacturing systems (RMS) capable of rapid adaptation to varying functionalities and capacities. However, current manufacturing system development methods often overlook product-driven changes during the system...journal article 2024
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Hemel, M. (author)Amsterdam faces the challenge of maintaining a domain of 200 km historic quay walls, which is a vital part of the city’s historical landscape. Many quays are currently in poor condition and require renovation or replacement in the near future, significantly impacting the city. The quay walls can be up to 300 years old and their structure...doctoral thesis 2023
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van Aalst, A.C.A. (author)The production of ethanol by the yeast Saccharomyces cerevisiae remains the process in industrial biotechnology with the largest product volume (ca. 100 million litres annually in 2022). Carbon losses occur due to the formation of biomass and glycerol, which can account for at least 8% of the product. Under anaerobic conditions, formation of...doctoral thesis 2023
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Persaud, S.M. (author), Flipsen, Bas (author)In September 2021, the faculty of Industrial Design Engineering (IDE) introduced a revamped bachelor's program that emphasizes design for higher complexity, teacher as a coach, and autonomous learning. The program includes Understanding Product Engineering (UPE), which teaches first-year design students about product embodiment, manufacturing,...conference paper 2023
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Baumgartner, L.M. (author)Electrochemical carbon dioxide reduction is a potential pathway to the sustainable production of hydrocarbon fuels and chemicals. This thesis explores the material science and reactor engineering of carbon dioxide electrolyzers.doctoral thesis 2023
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Dostanic, M. (author)The high death toll of cardiovascular diseases worldwide and the lack of effective treatments for them are the main motivation for developing alternative and more efficient models for cardiac drug development and disease research. The missing link between current laboratory research on static in vitro and animal models and the clinical stage...doctoral thesis 2023
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Putra, N.E. (author)The treatment of large bone injuries continues to be challenging partially due to the limited quantity and quality of bone-replacing materials. Iron (Fe) and its alloys have been developed as a group of load-bearing biomaterials. Recent advances in additive manufacturing (AM) have enhanced the potential of Fe-based biomaterials as biodegradable...doctoral thesis 2023
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Villalba, Víctor (author)Imagery collected from space provides very useful information about our planet. Today there are many Earth Observation satellites in orbit which allow us to collect information which is used for environmental monitoring, response to catastrophes, surveillance and security, urban planning, economic analysis and many other applications. Thus,...doctoral thesis 2023