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Abdelgawad, Ahmed A. (author), Comes, M. (author)Evaluation and testing are significant steps in developing any information system. More attention must be devoted to these steps if the system is to be used in high-risk contexts, such as the response to conflict disasters. Several testing methodologies are designed to guarantee that software fulfills technology requirements; others will assure...book chapter 2023
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van Dinten, I. (author), Zaidman, A.E. (author), Panichella, A. (author)Test case prioritization techniques have emerged as effective strategies to optimize this process and mitigate the regression testing costs. Commonly, black-box heuristics guide optimal test ordering, leveraging information retrieval (e.g., cosine distance) to measure the test case distance and sort them accordingly. However, a challenge...conference paper 2023
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Mooij, E. (author)Attitude control of conventional launchers is relatively easy and straightforward and gives an adequate performance when applied to the nominal vehicle and mission. However, in the presence of environmental disturbances and vehicle design uncertainties, more robust types of controllers are required to guarantee stable attitudes. This chapter...book chapter 2023
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Song, Y. (author)In the past decade, human digital twins (HDTs) attracted attention in both digital twin (DT) applications and beyond. In this paper, we discuss the concept and the development of HDTs, focusing on their architecture, key enabling technologies, and (potential) applications. Based on the literature, we identify personal data, model, and interface...review 2023
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Voskamp, Chantal (author), Koevoet, Wendy J.L.M. (author), van Osch, G.J.V.M. (author), Narcisi, Roberto (author)Introduction: Mesenchymal stromal/progenitor cells (MSCs) are promising for cartilage cell-based therapies due to their chondrogenic differentiation capacity. However, MSCs can become senescent during in vitro expansion, a state characterized by stable cell cycle arrest, metabolic alterations, and substantial changes in the gene expression and...journal article 2023
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Klaassen, R.G. (author), Bossen, R.H. (author), Milano, C. (author), Hellendoorn, J. (author)University students are asked to become all-round human beings, knowing how to be engaged in Engineering in the future, as well as wholly socialised and going through personal development steps. However, how and where are the students supposed to acquire these skills? Do we already have them in the Higher Education programmes and curricula?...conference paper 2023
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Hopster, J. (author), Brey, P. (author), Klenk, M.B.O.T. (author), Löhr, G. (author), Marchiori, S. (author), Lundgren, B. (author), Scharp, K. (author)This chapter provides a theoretical lens on conceptual disruption. It offers a typology of conceptual disruption, discusses its relation to conceptual engineering, and sketches a programmatic view of the implications of conceptual disruption for the ethics of technology. We begin by distinguishing between three different kinds of conceptual...book chapter 2023
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Eigbe, E. (author), De Schutter, B.H.K. (author), Nasri, Mitra (author), Yorke-Smith, N. (author)Industrial and academic interest converge on scheduling flow shops with sequence- and time-dependent maintenance. We posit that anticipatory, integrated scheduling of operational and maintenance tasks leads to superior performance to purely 'wait-then-fix' handling of the maintenance tasks. Motivated by an industrial problem with (sequence...journal article 2023
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Pitta Kruize, Carlos (author), Panahkhahi, S. (author), Putra, N.E. (author), Diaz Payno, P.J. (author), van Osch, G.J.V.M. (author), Zadpoor, A.A. (author), Mirzaali, Mohammad J. (author)Bone-to-soft tissue interfaces are responsible for transferring loads between tissues with significantly dissimilar material properties. The examples of connective soft tissues are ligaments, tendons, and cartilages. Such natural tissue interfaces have unique microstructural properties and characteristics which avoid the abrupt transitions...review 2023
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Mahler, M.S. (author), Martins Costa, A.R. (author), van Beljouw, S.P.B. (author), Fineran, Peter C. (author), Brouns, S.J.J. (author)In recent years, bacteriophage research has been boosted by a rising interest in using phage therapy to treat antibiotic-resistant bacterial infections. In addition, there is a desire to use phages and their unique proteins for specific biocontrol applications and diagnostics. However, the ability to manipulate phage genomes to understand and...review 2023
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Dell'Anna, D. (author), Aydemir, Fatma Başak (author), Dalpiaz, Fabiano (author)Context: Automated classifiers, often based on machine learning (ML), are increasingly used in software engineering (SE) for labelling previously unseen SE data. Researchers have proposed automated classifiers that predict if a code chunk is a clone, if a requirement is functional or non-functional, if the outcome of a test case is non...journal article 2023
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Muñoz, Paul (author), Corzo, Gerald (author), Solomatine, D.P. (author), Feyen, Jan (author), Célleri, Rolando (author)Extreme peak runoff forecasting is still a challenge in hydrology. In fact, the use of traditional physically-based models is limited by the lack of sufficient data and the complexity of the inner hydrological processes. Here, we employ a Machine Learning technique, the Random Forest (RF) together with a combination of Feature Engineering (FE...journal article 2023
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Carrete, I.A. (author), Ghodrat, S. (author), Scherer, Diana (author), Karana, E. (author)Plant root growth can be altered by introducing obstacles in the path of growth. This principle is used in design to produce planar grid structures composed of interweaving roots. The Engineered Plant Root Materials (EPRMs) grown with this method have the potential to serve as environmentally sensitive alternatives for conventional materials,...journal article 2023
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Veluwenkamp, H.M. (author), van den Hoven, M.J. (author)Politicians and engineers are increasingly realizing that values are important in the development of technological artefacts. What is often overlooked is that different conceptualizations of these abstract values lead to different design-requirements. For example, designing social media platforms for deliberative democracy sets us up for...journal article 2023
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Li, Yonghao (author), Zhang, Ning (author), Sun, Renjuan (author), Guan, Yanhua (author), Liu, Lemin (author), Tian, Changjin (author), Ling, Yifeng (author), Zhang, Hongzhi (author), Šavija, B. (author)The performance of engineered cementitious composites (ECCs) under coupled salt freezing and loaded conditions is important for its application on the transportation infrastructure. However, in most of the studies, the specimens were generally loaded prior to the freezing. The influence of sustained load was merely considered. To this end,...journal article 2023
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Tsitsilonis, Konstantinos Marios (author), Theotokatos, Gerasimos (author), Patil, Chaitanya (author), Coraddu, A. (author)The advancements in digital twins when combined with the use of the machine learning tools can facilitate the effective health assessment and diagnostics of safety critical systems. This study aims at developing a framework to address the health assessment of marine engines utilising digital twins based on first-principles. This framework...journal article 2023
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Xu, J. (author), Fahmy-Garcia, Shorouk (author), Wesdorp, Marinus A. (author), Forte, Lucia (author), De Luca, Claudio (author), Filardo, Giuseppe (author), Labberté, Margot (author), Kok, Joeri (author), Nickel, Joachim (author), van Osch, G.J.V.M. (author)Despite promising clinical results in osteochondral defect repair, a recently developed bi-layered collagen/collagen-magnesium-hydroxyapatite scaffold has demonstrated less optimal subchondral bone repair. This study aimed to improve the bone repair potential of this scaffold by adsorbing bone morphogenetic protein 2 (BMP-2) and/or platelet...journal article 2023
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Mitici, M.A. (author), de Pater, I.I. (author), Barros, Anne (author), Zeng, Zhiguo (author)The increasing availability of condition-monitoring data for components/systems has incentivized the development of data-driven Remaining Useful Life (RUL) prognostics in the past years. However, most studies focus on point RUL prognostics, with limited insights into the uncertainty associated with these estimates. This limits the...journal article 2023
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Li, Z. (author), Liu, Haoyuan (author), Hicks, M.A. (author), Pisano, F. (author)Offshore monopile foundations are exposed to misaligned wind and wave loadings, which are respectively dominated by (nearly) static and cyclic load components. While the response of these systems to unidirectional cyclic loading has been extensively investigated, only a few studies have been devoted to the realistic case of misaligned static...journal article 2023
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Zhou, J. (author), Menenti, M. (author), Jia, Li (author), Gao, Bo (author), Zhao, Feng (author), Cui, Yilin (author), Xiong, Xuqian (author), Liu, Xuan (author), Li, Dengchao (author)Spatiotemporal residual noise in terrestrial earth observation products, often caused by unfavorable atmospheric conditions, impedes their broad applications. Most users prefer to use gap-filled remote sensing products with time series reconstruction (TSR) algorithms. Applying currently available implementations of TSR to large-volume...journal article 2023