Techno-economic assessment of the use of solvents in the scale-up of microbial sesquiterpene production for fuels and fine chemicals

Sesquiterpenes are a group of versatile, 15-carbon molecules with applications ranging from fuels to fine chemicals and pharmaceuticals. When produced by microbial fermentation at laboratory scale, solvents are often employed for reducing product evaporation and enhancing recovery. However, it is not clear whether this approach constitutes a...

Towards the integration of fermentation and crystallisation - A study on the production of L-phenylalanine

Industrial biotechnology can be defined as the utilization of living organisms or their enzymes for the industrial production of food, beverages, commodity chemicals and pharmaceuticals, among others. A biotechnological production process, so-called bioprocess, mostly comprises product formation (e.g. by fermentation) and product recovery and...