Robust needle channel planning for patient-tailored applicator design in cervical cancer brachytherapy

Brachytherapy (BT) is an essential component in the treatment of cervical cancer as it allows for locally delivering a high dose to the tumour with minimal trauma to surrounding tissues and organs at risk (OARs). However, in advanced cervical cancer patients commercially available BT applicators are particularly ill-adapted and therefore result...

MRI-driven design of customised 3D printed gynaecological brachytherapy applicators with curved needle channels

Background:<br/> Brachytherapy involves placement of radioactive sources inside or near the tumour. For gynaecological cancer, recent developments, including 3D imaging and image-guided adaptive brachytherapy, have improved treatment quality and outcomes. However, for large or complex tumours, target coverage and local control with commercially...