Constructing phylogenetic networks via cherry picking and machine learning

Background: Combining a set of phylogenetic trees into a single phylogenetic network that explains all of them is a fundamental challenge in evolutionary studies. Existing methods are computationally expensive and can either handle only small numbers of phylogenetic trees or are limited to severely restricted classes of networks. Results: In...

Reconstructing Phylogenetic Networks via Cherry Picking and Machine Learning

Combining a set of phylogenetic trees into a single phylogenetic network that explains all of them is a fundamental challenge in evolutionary studies. In this paper, we apply the recently-introduced theoretical framework of cherry picking to design a class of heuristics that are guaranteed to produce a network containing each of the input...

Analysis of hydrogen-powered propulsion system alternatives for diesel-electric regional trains

Non-electrified regional railway lines with typically employed diesel-electric multiple units require alternative propulsion systems to meet increasingly strict emissions regulations. With the aim to identify an optimal alternative to conventional diesel traction, this paper presents a model-based assessment of hydrogen-powered propulsion...

A hybrid mimetic spectral element method for three-dimensional linear elasticity problems

We introduce a domain decomposition structure-preserving method based on a hybrid mimetic spectral element method for three-dimensional linear elasticity problems in curvilinear conforming structured meshes. The method is an equilibrium method which satisfies pointwise equilibrium of forces. The domain decomposition is established through...

A high order hybrid mimetic discretization on curvilinear quadrilateral meshes for complex geometries

In this paper, we present a hybrid mimetic method which solves the mixed formulation of the Poisson problem on curvilinear quadrilateral meshes. The method is hybrid in the sense that the domain is decomposed into multiple disjoint elements and the interelement continuity is enforced using a Lagrange multiplier. The method is mimetic in the...

A Hybrid Readout Solution for GaN-Based Detectors Using CMOS Technology

Gallium nitride (GaN) and its alloys are becoming preferred materials for ultraviolet (UV) detectors due to their wide bandgap and tailorable out-of-band cutoff from 3.4 eV to 6.2 eV. GaN based avalanche photodiodes (APDs) are particularly suitable for their high photon sensitivity and quantum efficiency in the UV region and for their...

Selection of Pof^- saccharomyces eubayanus variants for the construction of S. cerevisiae × S. eubayanus hybrids with reduced 4-Vinyl guaiacol formation

Saccharomyces pastorianus is an interspecies hybrid between S. cerevisiae and S. eubayanus. The identification of the parental species of S. pastorianus enabled the de novo reconstruction of hybrids that could potentially combine a wide array of phenotypic traits. Lager yeasts are characterized by their inability to decarboxylate ferulic acid...