Design and Development of Integrated Displacement Sensors for Engineered Heart Tissue Platforms

Cardiac cells derived from stem cells exhibit cellular contractions when cultured in vitro. They can be integrated with polymeric platforms consisting of micropillars, which act as anchors and pre-load for engineered heart tissue (EHT). The biomechanical response is often characterized using optical microscopy to track the displacement of pillar...

Design and Custom Fabrication of a Smart Temperature Sensor for an Organ-on-a-chip Platform

This paper reports on the design and fabrication of a time-mode signal-processing in situ temperature sensor customized for an organ-on-a-chip (OOC) application. The circuit was fabricated using an in-house integrated circuit (IC) technology that requires only seven lithographic steps and is compatible with MEMS fabrication process. The...