Estimation of multiple components and parameters for quantitative MRI

Magnetic Resonance Imaging (MRI) is a flexible medical imaging technique that facilitates measurement of a wide range of contrasts particularly in soft tissue (e.g. brain and heart). Conventionally, qualitative images are acquired in which certain physical tissue properties are emphasized such as the transverse and longitudinal relaxation times....

Accuracy and repeatability of joint sparsity multi-component estimation in MR Fingerprinting

MR fingerprinting (MRF) is a promising method for quantitative characterization of tissues. Often, voxel-wise measurements are made, assuming a single tissue-type per voxel. Alternatively, the Sparsity Promoting Iterative Joint Non-negative least squares Multi-Component MRF method (SPIJN-MRF) facilitates tissue parameter estimation for...

Multicomponent MR fingerprinting reconstruction using joint-sparsity and low-rank constraints

Purpose: To develop an efficient algorithm for multicomponent MR fingerprinting (MC-MRF) reconstructions directly from highly undersampled data without making prior assumptions about tissue relaxation times and expected number of tissues. Methods: The proposed method reconstructs MC-MRF maps from highly undersampled data by iteratively...

Mitigating undersampling errors in MR fingerprinting by sequence optimization

Purpose: To develop a method for MR Fingerprinting (MRF) sequence optimization that takes both the applied undersampling pattern and a realistic reference map into account. Methods: A predictive model for the undersampling error leveraging on perturbation theory was exploited to optimize the MRF flip angle sequence for improved robustness...

Fast multi-component analysis using a joint sparsity constraint for MR fingerprinting

<br/>Purpose<br/><br/>To develop an efficient algorithm for multi‐component analysis of magnetic resonance fingerprinting (MRF) data without making a priori assumptions about the exact number of tissues or their relaxation properties.<br/>Methods<br/><br/>Different tissues or components within a voxel are potentially separable in MRF because of...