Searched for: subject%3A%22Rat%22
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Warmink, Kelly (author), Rios, Jaqueline L. (author), Varderidou-Minasian, Suzy (author), Torres-Torrillas, Marta (author), van Valkengoed, Devin R. (author), Versteeg, Sabine (author), Eijkelkamp, Niels (author), Weinans, Harrie (author), Korthagen, Nicoline M. (author), Lorenowicz, Magdalena J. (author)
Background: Mesenchymal stromal/stem cells (MSCs) and MSC-derived extracellular vesicles (MSC-EVs) hold promise as a disease modifying treatment in osteoarthritis (OA). Obesity, and its associated inflammation, contribute to OA development and metabolic OA represents a specific and significant group of the OA patient population. Given their...
journal article 2023
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La Zara, D. (author), Sun, F. (author), Zhang, F. (author), Franek, Frans (author), Balogh Sivars, Kinga (author), Horndahl, Jenny (author), Bates, Stephanie (author), Brännström, Marie (author), van Ommen, J.R. (author)
Ideal controlled pulmonary drug delivery systems provide sustained release by retarding lung clearance mechanisms and efficient lung deposition to maintain therapeutic concentrations over prolonged time. Here, we use atomic layer deposition (ALD) to simultaneously tailor the release and aerosolization properties of inhaled drug particles...
journal article 2021
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Güvenir, Su (author)
Glaucoma is the leading cause of irreversible blindness and in 2040, more than 111 million people are expected to have the disease. Vision loss in glaucoma is caused by the death of retinal ganglion cells (RGCs) primarily in the optic nerve head (ONH). Elevated intraocular pressure (IOP) is a well-known causative risk factor for glaucoma,...
master thesis 2018
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Ólafsdóttir, Guðrún Erla (author)
When the neural pathway within the spinal cord gets damaged, a person’s ability to initiate loco- motion can be affected. Currently, no restorative treatments exist for individuals that suffer from such an injury. However, recent studies have shown epidural spinal cord stimulation (ESCS) to be a potential option for re-establishing some...
master thesis 2017
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Vijverberg, J.W. (author)
Background: Aseptic loosening [AL] of cementless implants is causing approximately 60% of total knee and total hip arthroplasty revisions. AL is caused among other factors by micromotion. The result is that the bone around the prosthesis is replaced by a fibrous membrane. This fibrous membrane allows for more micromotion and we thus enter a...
master thesis 2016
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Zervakis, D.I. (author)
All human life is dependent on fresh water and activities related to monitoring its availability have become crucial for financial and survival reasons. Most rivers are being constantly investigated today by both the private and public sector using various means. In advanced countries, the researches cover extensively the riverbed in order to...
master thesis 2015
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Khmelinskii, A. (author), Baiker, M. (author), Kaijzel, E.L. (author), Chen, J. (author), Reiber, J.H.C. (author), Lelieveldt, B.P.F. (author)
Purpose Using three publicly available small-animal atlases (Sprague–Dawley rat, MOBY, and Digimouse), we built three articulated atlases and present several applications in the scope of molecular imaging. Procedures Major bones/bone groups were manually segmented for each atlas skeleton. Then, a kinematic model for each atlas was built: each...
journal article 2010
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Beekman, F.J. (author), Vastenhouw, B. (author), Van der Wilt, G. (author), Vervloet, M. (author), Visscher, R. (author), Booij, J. (author), Gerrits, M. (author), Ji, C. (author), Ramakers, R. (author), Van der Have, F. (author)
With the steadily improving resolution of novel small-animal single photon emission computed tomography (SPECT) and positron emission tomography devices, highly detailed phantoms are required for testing and optimizing these systems. We present a three-dimensional (3-D) digital and physical phantom pair to represent, e.g., cerebral blood flow,...
journal article 2009
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van den Berg, G.J. (author)
doctoral thesis 1993
Searched for: subject%3A%22Rat%22
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