Uncoupling yeast growth and product formation in chemostat and retentostat cultures

The progress of modern biotechnology has enabled the development of fermentation processes for the production of fuels and chemicals from renewable feedstocks. The current fermentation processes for bio-based production commonly start with a growth phase of the microorganisms followed by a production phase. This implies that biomass formation...

Temperature impact on yeast metabolism: Insights from experimental and modeling approaches

Temperature is an environmental parameter that greatly affects the growth of microorganisms, due to its impact on the activity of all enzymes in the network. This is particularly relevant in habitats where there are large temperature changes, either daily or seasonal. Understanding how organisms have adapted to cope with these temperature-cycles...

Short term step responses of central carbon and storage metabolism in Saccharomyces cerevisiae: novel minibioreactors and 13C studies