Searched for: subject%3A%22STEM%22
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Bolhuis, M. (author), van Heijst, S.E. (author), Sangers, J.J.M. (author), Conesa Boj, S. (author)
Achieving nanoscale strain fields mapping in intricate van der Waals (vdW) nanostructures, like twisted flakes and nanorods, presents several challenges due to their complex geometry, small size, and sensitivity limitations. Understanding these strain fields is pivotal as they significantly influence the optoelectronic properties of vdW...
journal article 2024
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Angelini, Franco (author), Angelini, Pierangela (author), Angiolini, Claudia (author), Bagella, Simonetta (author), Caccianiga, Marco (author), Della Santina, C. (author), Gigante, Daniela (author), Hutter, Marco (author), Nanayakkara, Thrishantha (author)
In this paper, we first discuss the challenges related to habitat monitoring and review possible robotic solutions. Then, we propose a framework to perform terrestrial habitat monitoring exploiting the mobility of legged robotic systems. The idea is to provide the robot with the Natural Intelligence introduced as the combination of the...
journal article 2023
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Zhou, Liangbin (author), Xu, J. (author), Schwab, Andrea (author), Tong, Wenxue (author), Zheng, Lizhen (author), Li, Zhuo (author), Xu, Shunxiang (author), van Osch, G.J.V.M. (author), Wen, Chunyi (author), Qin, Ling (author)
As a highly specialized shock-absorbing connective tissue, articular cartilage (AC) has very limited self-repair capacity after traumatic injuries, posing a heavy socioeconomic burden. Common clinical therapies for small- to medium-size focal AC defects are well-developed endogenous repair and cell-based strategies, including microfracture,...
review 2023
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Zhu, C. (author), Leung, Chloe Oi Ying (author), Lagoudaki, Eleni (author), Velho, Mariana (author), Segura Caballero, N. (author), Jolles, Dietsje (author), Duffy, Gavin (author), Maresch, Günter (author), Pagkratidou, Marianna (author), Klapwijk, R.M. (author)
Empirical interdisciplinary research has explored the role of spatial ability in STEM learning and achievement. While most of this research indicates that fostering spatial thinking in educational contexts has the potential to positively impact students’ enrollment and performance in STEM subjects, there is less agreement on the best approach...
review 2023
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Warmink, Kelly (author), Rios, Jaqueline L. (author), Varderidou-Minasian, Suzy (author), Torres-Torrillas, Marta (author), van Valkengoed, Devin R. (author), Versteeg, Sabine (author), Eijkelkamp, Niels (author), Weinans, Harrie (author), Korthagen, Nicoline M. (author), Lorenowicz, Magdalena J. (author)
Background: Mesenchymal stromal/stem cells (MSCs) and MSC-derived extracellular vesicles (MSC-EVs) hold promise as a disease modifying treatment in osteoarthritis (OA). Obesity, and its associated inflammation, contribute to OA development and metabolic OA represents a specific and significant group of the OA patient population. Given their...
journal article 2023
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Skoupý, R. (author), Boltje, D.B. (author), Slouf, Miroslav (author), Mrázová, Kateřina (author), Láznička, Tomáš (author), Taisne, C.M. (author), Krzyžánek, Vladislav (author), Hoogenboom, J.P. (author), Jakobi, A. (author)
A quantitative four-dimensional scanning transmission electron microscopy (4D-STEM) imaging technique (q4STEM) for local thickness estimation across amorphous specimen such as obtained by focused ion beam (FIB)-milling of lamellae for (cryo-)TEM analysis is presented. This study is based on measuring spatially resolved diffraction patterns to...
journal article 2023
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Velot, Émilie (author), Balmayor, Elizabeth R. (author), Bertoni, Lélia (author), Chubinskaya, Susan (author), Cicuttini, Flavia (author), de Girolamo, Laura (author), Demoor, Magali (author), van Osch, G.J.V.M. (author), Cucchiarini, Magali (author)
review 2023
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Berenger-Currias, N.M.L.P. (author)
Embryogenesis is a fascinating mystery. How a single fertilized egg, the zygote, reads out its genetic information and turns into a fully formed, multicellular organism still defies detailed understanding. <br/>An adult organism can consist of trillions of cells of different types, organized to form various complex tissues and organs. To obtain...
doctoral thesis 2022
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Castillo Ransanz, Lucía (author), van Altena, P.F.J. (author), Heine, Vivi M. (author), Accardo, A. (author)
The biomechanical properties of the brain microenvironment, which is composed of different neural cell types, the extracellular matrix, and blood vessels, are critical for normal brain development and neural functioning. Stiffness, viscoelasticity and spatial organization of brain tissue modulate proliferation, migration, differentiation, and...
review 2022
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book 2022
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Jansen, Marc (author), Fanchamps, L.J.A. (author), Milrad, Marcelo (author), Specht, M.M. (author), Hamidi, Ali (author)
One major challenge the educational community is facing relates to how to effectively integrate computational thinking (CT) concepts and ideas into a particular school curriculum. Acquiring CT-skills by means of STEM offers rich opportunities within students´ education which may lead to learning gains. Previous research has shown that, to...
conference paper 2022
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Melsen, Janine E. (author), van Ostaijen-ten Dam, Monique M. (author), van den Akker, E.B. (author), Welters, Marij J.P. (author), Heezen, Kim C. (author), Pico-Knijnenburg, Ingrid (author), Kolijn, P.M. (author), Bredius, Robbert G.M. (author), van Doorn, Remco (author)
The first successful European hematopoietic stem cell transplantation (HSCT) was performed in 1968 as treatment in a newborn with IL2RG deficiency using an HLA-identical sibling donor. Because of declining naive T and natural killer (NK) cells, and persistent human papilloma virus (HPV)-induced warts, the patient received a peripheral stem...
journal article 2022
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Neves Leal Costa, B. (author), Adão, Ricardo M.R. (author), Maibohm, Christian (author), Accardo, A. (author), Cardoso, Vanessa F. (author), Nieder, Jana B. (author)
Biomimicking biological niches of healthy tissues or tumors can be achieved by means of artificial microenvironments, where structural and mechanical properties are crucial parameters to promote tissue formation and recreate natural conditions. In this work, three-dimensional (3D) scaffolds based on woodpile structures were fabricated by two...
journal article 2022
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Berenger-Currias, N.M.L.P. (author), Mircea, Maria (author), Adegeest, Esmée (author), van den Berg, Patrick R. (author), Feliksik, Marleen (author), Hochane, Mazène (author), Idema, T. (author), Tans, S.J. (author), Semrau, Stefan (author)
Stem-cell derived in vitro systems, such as organoids or embryoids, hold great potential for modeling in vivo development. Full control over their initial composition, scalability, and easily measurable dynamics make those systems useful for studying specific developmental processes in isolation. Here we report the formation of gastruloids...
journal article 2022
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Daneshpour Aryadi, H. (author)
Tales of a Fountain of Youth and the invention of medicine illustrate our age-long obsession with two themes: life and death. What it takes to stay alive, and not to be dead, is a basic question in science that is easy to state, and yet difficult to address at a profound level. One striking feature of many living organisms is the ability of...
doctoral thesis 2021
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Stevens, L.L. (author)
“Teaching is both an art and a science” (Harrison &amp; Coll, 2008 p.1). Good teaching excites students and cultivates their curiosity to learn more than they are asked. But what if students’ blank faces tell you that the teaching did not land, what can you do? Using an analogy or metaphor to explain the principle helps students visualize and...
doctoral thesis 2021
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Mastrangeli, Massimo (author), van den Eijnden-van Raaij, A.J.M. (author)
Organ-on-chip (OoC) technology is thriving thanks to stem cells availability and international OoC programs. Concerted standardization, qualification, and independent testing of devices are needed to coherently develop OoC technology further and fulfill its potential in drug development, disease modeling, and personalized medicine. The OoC...
journal article 2021
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Dostanic, M. (author), Stein, Jeroen (author), Windt, Laura (author), van Meer, Berend (author), Bellin, Milena (author), Orlova, Valeria (author), Mastrangeli, Massimo (author), Mummery, Christine (author), Sarro, Pasqualina M (author)
We present a wafer-scale fabricated, PDMS-based platform for culturing miniaturized engineered heart tissues (EHTs) which allows highly accurate measurements of the contractile properties of these tissues. The design of the platform is an anisometrically downscaled version of the Heart-Dyno system, consisting of two elastic micropillars inside...
journal article 2020
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Guo, Y. (author)
Electron tomography is a powerful tool in materials science to characterize nanostructures in three dimensions (3D). In scanning transmission electron microscopy (STEM), the sample under study is exposed to a focused electron beam and tilted to obtain twodimensional (2D) projections at different angles; many imaging modes are available such as...
doctoral thesis 2020
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Watts, Abigail E. (author), Lozinska, Magdalena M. (author), Slawin, Alexandra M.Z. (author), Mayoral, Alvaro (author), Dawson, Daniel M. (author), Ashbrook, Sharon E. (author), Bode, Bela E. (author), Dugulan, A.I. (author), Shannon, Mervyn D. (author)
An AlPO<sub>4</sub> zeotype has been prepared using the aromatic diamine 1,10-phenanthroline and some of its methylated analogues as templates. In each case the two template N atoms bind to a specific framework Al site to expand its coordination to the unusual octahedral AlO<sub>4</sub>N<sub>2</sub> environment. Furthermore, using this...
journal article 2020
Searched for: subject%3A%22STEM%22
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