Thermal ablation of primary liver tumors: Correspondence of the predicted ablation zone with the clinically obtained ablation zone

<b>Purpose</b> Manufacturer’s predictions of ablation zone dimensions are the current directives for treatment planning in thermal ablation, while they are mostly based on ex vivo experiments making its reliability questionable. The aim of this study is to determine the correspondence in dimensions, volume, shape and overlap of the manufactures’...

Simulation of temperature and dose distribution of a proposed minimally invasive treatment of early‐stage breast cancer by combining thermal ablation and LDR brachytherapy using Pd-103 SPIO nanoparticles

Treatment of early stage breast cancer is generally invasive to a patient's daily life while being treated. Therefore, to diminish the physical and psychological impact during and after recovery, a newly proposed minimally invasive therapy for early-stage breast cancer treatment is proposed. Within this study, this proposed treatment is modelled...

Feasibility Study on the Radiation Dose by Radioactive Magnetic Core-Shell Nanoparticles for Open-Source Brachytherapy

Background: Treatment of early-stage breast cancer currently includes surgical removal of the tumor and (partial) breast irradiation of the tumor site performed at fractionated dose. Although highly effective, this treatment is exhaustive for both patient and clinic. In this study, the theoretical potential of an alternative treatment combining...

Synthesis of PdO-USPION via Spark Ablation: For Thermal Ablation and Contrast Enhancement

Conventional early-stage breast cancer treatments such as surgery, chemotherapy and external radiotherapy despite their proven short-term efficacy tend to have adverse long-term physiological and psychological implications on the patients. This is primarily due to their inability to spare healthy tissue surrounding the tumor...

Quantitative three-dimensional evaluation of ablation margins for the prediction of local tumor progression

<b>Introduction</b> The objective of this research is to assess whether there is a correlation between quantitatively assessed ablation margins and the occurrence of local tumor progression (LTP) using dedicated image processing software.<br/><b>Methods</b> 28 patients with 45 de novo HCCs treated with percutaneous thermal ablation, e.g....

Comparison of the tissue interaction between thermal ablation and cryotherapy as treatment for cervical precancerous lesions in an ex-vivo model

Both cryotherapy and thermal ablation are treatment methods for cervical precancerous lesions in screening programs in resource constrained settings. However, for thermal ablation the World Health Organization stated that there is insufficient data to define a standard treatment protocol. This study used an ex-vivo model to compare the tissue...

Needle deflection in thermal ablation procedures of liver tumors: a CT image analysis

Introduction: Accurate needle placement is crucial in image-guided needle interventions. A targeting error may be introduced due to undesired needle deflection upon insertion through tissue, caused by e.g. patient breathing, tissue heterogeneity, or asymmetric needle tip geometries. This paper aims to quantify needle deflection in thermal...