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Hopf, Y.M. (author)This thesis describes the design of application-specific integrated circuits (ASICs) for high-frame-rate 3D intracardiac echocardiography (ICE) probes. The work follows the whole process from the analysis of the application to the testing of a prototype with all envisioned functionality. It starts with the evaluation of the main challenges posed...doctoral thesis 2023
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Savundranayagam, Reka (author)In vitro neuromodulation studies play a crucial role in understanding the underlying interaction mechanisms between cells and ultrasound, which is important in the development of new therapies for various neurological disorders. Acoustic focusing, the ability to focus ultrasound at a specific focal length with high spatial resolution, provides a...master thesis 2023
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van der Meulen, P.Q. (author)Whereas aberrating layers are typically viewed as an impediment to medical ultrasound imaging, they can, surprisingly, also be used to our benefit. As long as we can model the effect of an aberrating layer, we can utilize ‘model-based imaging’, the imaging technique explored throughout this thesis, to reconstruct ultrasound images where...doctoral thesis 2023
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WEI, LAI (author)3-D ultrasound imaging using a 2-D array provides much more information about our body than conventional 2-D imaging. However, due to the large number of elements in a 2-D array, channel count reduction is required and the power and area budget for each element is limited. It is quite challenging to design an ultrasound interface circuit with...master thesis 2023
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Saha, S. (author), Luckham, Paul F. (author), Garbin, V. (author)Hypothesis: High-frequency interfacial rheology of complex interfaces remains challenging yet it is central to the performance of multiphase soft matter products. We propose to use ultrasound-driven bubble dynamics to probe the high-frequency rheology of a colloid monolayer used as model system with controlled interactions and simultaneous...journal article 2023
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Howard, Thomas (author), Driller, K.K. (author), Frier, William (author), Pacchierotti, Claudio (author), Marchal, Maud (author), Hartcher-O'Brien, J. (author)Ultrasound mid-air haptic (UMH) devices are a novel tool for haptic feedback, capable of providing localized vibrotactile stimuli to users at a distance. UMH applications largely rely on generating tactile shape outlines on the users' skin. Here we investigate how to achieve sensations of continuity or gaps within such two-dimensional curves...journal article 2023
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Li, H. (author), Li, X. (author), Collado Lara, G. (author), Lattwein, K.R. (author), Mastik, Frits (author), Beurskens, Robert (author), van der Steen, A.F.W. (author), Verweij, M.A. (author), de Jong, N. (author), Kooiman, Klazina (author)Ultrasound contrast-mediated medical imaging and therapy both rely on the dynamics of micron- and nanometer-sized ultrasound cavitation nuclei, such as phospholipid-coated microbubbles and phase-change droplets. Ultrasound cavitation nuclei respond non-linearly to ultrasound on a nanosecond time scale that necessitates the use of ultra-high...journal article 2023
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Zhao, Wenzhao (author), Fan, Yuling (author), Wang, Hongjian (author), Gemmeke, Hartmut (author), van Dongen, K.W.A. (author), Hopp, Torsten (author), Hesser, Jürgen (author)Objective. The image reconstruction of ultrasound computed tomography is computationally expensive with conventional iterative methods. The fully learned direct deep learning reconstruction is promising to speed up image reconstruction significantly. However, for direct reconstruction from measurement data, due to the lack of real labeled...journal article 2023
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Dia, Amadou Sall (author), Renaud, G.G.J. (author), Nooghabi, Aida Hejazi (author), Grimal, Quentin (author)Decreased thickness of the bone cortex due to bone loss in the course of ageing and osteoporosis is associated with reduced bone strength. Cortical thickness measurement from ultrasound images was recently demonstrated in young adults. This requires the identification of both the outer (periosteum) and inner (endosteum) surfaces of the bone...journal article 2023
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Saccher, M. (author), Kawasaki, S. (author), Klootwijk, Johan (author), van Schaijk, Rob (author), Dekker, R. (author)Recently, the applications of ultrasound transducers expanded from high-end diagnostic tools to point of care diagnostic devices and wireless power receivers for implantable devices. These new applications additionally require that the transducer technology must comply to biocompatibility and manufacturing scalability. In this respect,...journal article 2023
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Bekkers, Amerens (author)Introduction: Coronary atherosclerosis can form large lipid-rich plaques inside the arteries, which are prone to rupture. Rupture can lead to thrombus formation and subsequent obstruction of the blood flow, which is the most common cause of acute coronary events like myocardial infarction. Current imaging modalities lack the ability to image...master thesis 2022
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Tesselaar, Izaka (author)Introduction – Cardiovascular diseases are the leading cause of death in the world with one in three succumbing to the disease. The most common cardiovascular disease is coronary artery disease, caused by atherosclerosis resulting in a build-up of plaque within the arteries. This plaque can progress into a vulnerable plaque, which has been...master thesis 2022
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Sluijter, Judith (author)Wrong-level spine surgery (WLS) is a medical error with severe consequences for the patient and medical staff. The current golden standard to prevent WLS during spinal surgery is fluoroscopy images acquired by a C-arm. However, this approach uses ionising radiation and interrupts the standard surgical workflow. To overcome these disadvantages,...master thesis 2022
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Donse, Daniël (author)Background: The procedure to fit a prosthetic socket to a patient, which can assure the patient’s comfort during activities of daily living, is labour intensive. Such a lengthy procedure could benefit from an automated and more efficient data-driven method capable of automatically tracking the relative movement between the patient’s tibia and...master thesis 2022
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Lolla, Sai Sandeep (author)Implantable Medical Devices (IMDs) offer a wide range of applications including but not limited to blood pressure monitoring, bladder pressure sensing, glucose level monitoring, neurostimulation etc. For such applications, it is often desired that an IMD is as small as possible while meeting the required objective. Consequently, using a battery...master thesis 2022
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Hintzen, Annemijn (author)Elongated mechanical ventilation is associated with ventilator-induced lung injury (VILI), diaphragmatic muscle atrophy, patient discomfort, increased mortality rates and higher healthcare costs. However, hospitals are lacking in user-friendly, affordable and accurate methods to measure the decline the respiratory condition. Computed tomography ...master thesis 2022
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Burghoorn, Niels (author)Medical technology has seen great progress over the last centuries, developing increasingly more specialised therapy to benefit human health. The rise of the pharmaceutical industry and the research it drives are contributors to this success. However, in humanity's attempt to tackle more and more complex health issues, the conventional methods...master thesis 2022
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Xiao, Yidi (author)Noninvasive brain stimulation plays an essential role in diagnosing and treating diseases of the brain. This stimulation can affect disease-related changes in brain activation, inhibition, or connectivity. Ultrasound neuromodulation is a rapidly growing field of noninvasive brain stimulation. In a form of acoustic pressure waves, ultrasound can...master thesis 2022
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Tao, Yitong (author)To better understand how brain signals are processed and even how the human mind works, analyzing the hemodynamic signal model is one of the most essential steps. In the CUBE group of Erasmus MC, functional ultrasound (fUS) data of a mouse’s brain is recorded. By using this fUS dataset, this thesis will solve the problem regarding the joint...master thesis 2022
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van Willigen, D.M. (author)This thesis describes the design, prototyping and evaluation of matrix-based clamp-on ultrasonic flow meters. Several new measurement techniques are presented as well as an Application-Specific Integrated Circuit (ASIC) designed for accurate measurement of flow velocity with matrix transducers.<br/><br/>The influence of circuit topologies on the...doctoral thesis 2022