Searched for: subject:"aberrations"
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Van Dyk, H.O. (author)
Cancer is a genetic disease. The activation, alteration or deactivation of cancer genes can stimulate undesirable cell-proliferation. Cancer genes can be subdivided into oncogenes and tumor suppressors. Oncogenes, such as growth factor receptors, are altered and/or overexpressed genes that are causally linked to tumorigenesis. Tumor suppressors,...
doctoral thesis 2019
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Dwivedi, P. (author), Pereira, S.F. (author), Urbach, Paul (author)
Wavefront aberration measurements are required to test an extreme ultraviolet (EUV) imaging system. For a high-NA EUV imaging system, where conventional wavefront-sensing techniques show limitations, ptychography can be used for this purpose. However, at the wavelength region of EUV (i.e., 13.5 nm), the position accuracy of the scanning mask...
journal article 2019
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Wilding, D. (author)
The goal of this thesis, called Physical and Computational Approaches to Aberration Correction In Fluorescence Microscopy, concerns itself with the development of new techniques to control adaptive fluorescence microscopes, so that they can adapt and image with increased resolution, contrast and speed inside complex three-dimensional biological...
doctoral thesis 2018
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Tinoco Rivas, M. (author), Maduro, L.A. (author), Masaki, Mukai (author), Okunishi, Eiji (author), Conesa Boj, S.C. (author)
Edge structures are low-dimensional defects unavoidable in layered materials of the transition metal dichalcogenides (TMD) family. Among the various types of such structures, the armchair (AC) and zigzag (ZZ) edge types are the most common. It has been predicted that the presence of intrinsic strain localized along these edges structures can...
journal article 2017
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Habets, Michel (author), Scholten, Joni (author), Weiland, Siep (author), Coene, W.M.J.M. (author)
The imaging quality of the projection optics of an extreme ultraviolet lithography scanner degrades under the influence of thermally induced deformations of its mirrors. Wavefronts of different reticle points encounter different parts of the deformed mirrors, resulting in a field dependent wavefront error. This paper presents how ideas from...
conference paper 2016
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Agbana, T.E. (author), Yang, H. (author), Soloviev, O.A. (author), Vdovine, Gleb (author), Verhaegen, M.H.G. (author)
This paper presents experimental results of a static aberration control algorithm based on the linear relation be- tween mean square of the aberration gradient and the second moment of point spread function for the generation of control signal input for a deformable mirror (DM). Results presented in the work of Yang et al.1 suggested a good...
conference paper 2016
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Schouten, P.C. (author), Grigoriadis, A. (author), Kuilman, T. (author), Mirza, H. (author), Watkins, J.A. (author), Cooke, S.A. (author), Van Dyk, E. (author), Severson, T.M. (author), Rueda, O.M. (author), Hoogstraat, M. (author), Verhagen, C. (author), Natrajan, R. (author), Chin, S.F. (author), Lips, E.H. (author), Kruizinga, J. (author), Velds, A. (author), Nieuwland, M. (author), Kerkhoven, R.M. (author), Krijgsman, O. (author), Vens, C. (author), Peeper, D. (author), Nederlof, P.M. (author), Caldas, C. (author), Tutt, A.N. (author), Wessels, L.F.A. (author), Linn, S.C. (author)
Breast cancers with BRCA1 germline mutation have a characteristic DNA copy number (CN) pattern. We developed a test that assigns CN profiles to be ‘BRCA1-like’ or ‘non-BRCA1-like’, which refers to resembling a BRCA1-mutated tumor or resembling a tumor without a BRCA1 mutation, respectively. Approximately one third of the BRCA1-like breast...
journal article 2015
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Shakeri, S.M. (author), Hulsken, B. (author), Van Vliet, L.J. (author), Stallinga, S. (author)
Whole Slide Imaging (WSI) systems are used in the emerging field of digital pathology for capturing high-resolution images of tissue slides at high throughput. We present a technique to measure the optical aberrations of WSI systems using a Shack-Hartmann wavefront sensor as a function of field position. The resulting full-field aberration maps...
conference paper 2015
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Yoo, H.W. (author), Royen, M.E. (author), van Cappellen, W.A. (author), Houtsmuller, A.B. (author), Verhaegen, M.H.G. (author), Schitter, G. (author)
Mismatch between the refractive indexes of immersion media and glass coverslips introduces spherical aberrations in microscopes especially for high numerical aperture objectives. This contribution demonstrates an automated adjustment of the coverslip correction collar in scanning confocal microscopy to compensate for spherical aberrations due to...
journal article 2014
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Antonello, J. (author)
Microscopy is an essential tool for life sciences. Thanks to the development of confocal and multiphoton microscopy, scientists are able to obtain high-resolution 3D views of biological specimens. Nevertheless, spatial variations in the index of refraction within specimens cause aberrations that degrade the quality of the 3D views. One can...
doctoral thesis 2014
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Antonello, J. (author), Van Werkhoven, T. (author), Verhaegen, M. (author), Truong, H.H. (author), Keller, C.U. (author), Gerritsen, H.C. (author)
Optical aberrations have detrimental effects in multiphoton microscopy. These effects can be curtailed by implementing model-based wavefront sensorless adaptive optics, which only requires the addition of a wavefront shaping device, such as a deformable mirror (DM) to an existing microscope. The aberration correction is achieved by maximizing a...
journal article 2014
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Van Werkhoven, T.I.M. (author), Antonello, J. (author), Truong, H.H. (author), Verhaegen, M. (author), Gerritsen, H.C. (author), Keller, C.U. (author)
Deep imaging in turbid media such as biological tissue is challenging due to scattering and optical aberrations. Adaptive optics has the potential to compensate the tissue aberrations. We present a wavefront sensing scheme for multi-photon scanning microscopes using the pulsed, near-infrared light reflected back from the sample utilising...
journal article 2014
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Saathof, R. (author)
In highly precise systems the thermal expansion of system-parts is of increasing concern, since it can severely compromise its performance at sub-nanometre level. An example of such a system is an Extreme UltraViolet (EUV)-lithography machine that is used in the semi-conductor industry to project the pattern of the chip onto a silicon wafer. In...
doctoral thesis 2013
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Valentin, C.L. (author)
This thesis investigates the feasibility of a photomask curvature manipulator in immersion lithography systems.
doctoral thesis 2013
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Pereira, S.F. (author), Wiegman, A. (author), Kumar, N. (author), Da Costa Assafrao, A. (author), Polo, A. (author), Wei, L. (author), Van Haver, S. (author)
Measurement techniques to determine the aberration of an optical system, by obtaining through-focus intensity images that are produced when the object is a point source at infinity, are shown. The analysis of the aberrations is made using the extended version of the Nijboer-Zernike diffraction theory. This theory provides a semi analytical...
conference paper 2012
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Van Haver, S. (author), Braat, J.J.M. (author), Pereira, S.F. (author)
We propose a measurement approach that allows the determination of aberrations of a microlens by analyzing the through-focus intensity image it produces when the object is a point source. To simulate image formation by a microlens we apply the extended version of the Nijboer-Zernike diffraction theory (ENZ) that uses the Debye diffraction...
conference paper 2010
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Mahajan, V.N. (author), Aftab, M. (author)
The theory of wavefront analysis of a noncircular wavefront is given and applied for a systematic comparison of the use of annular and Zernike circle polynomials for the analysis of an annular wavefront. It is shown that, unlike the annular coefficients, the circle coefficients generally change as the number of polynomials used in the expansion...
journal article 2010
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Song, H. (author), Fraanje, R. (author), Schitter, G. (author), Kroese, H. (author), Vdovin, G. (author), Verhaegen, M. (author)
In many scientific and medical applications, such as laser systems and microscopes, wavefront-sensor-less (WFSless) adaptive optics (AO) systems are used to improve the laser beam quality or the image resolution by correcting the wavefront aberration in the optical path. The lack of direct wavefront measurement in WFSless AO systems imposes a...
journal article 2010
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Van Haver, S. (author)
In present-day society, we encounter optical systems on a daily basis. Most people have a DVD player capable of playing content stored on an optical disc, Big Brother is watching us nearly everywhere using surveillance cameras and we consider it to be normal to take photographs with our mobile phone. Also, in less visible areas, such as...
doctoral thesis 2010
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Hagen, C.W. (author), Kruit, P. (author)
The authors have analyzed how much current can be obtained in the probe of an optimized two-lens focused ion beam (FIB) system. This becomes relevant, as systems become available that have the potential to image and/or fabricate structures smaller than 10 nm. The probe current versus probe size curves were calculated for a commercial gallium-FIB...
journal article 2009
Searched for: subject:"aberrations"
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