Searched for: subject:"atherosclerosis"
(1 - 9 of 9)
document
Nieuwstadt, H.A. (author), Van der Lugt, A. (author), Kassar, Z.A.M. (author), Breeuwer, M. (author), Van der Steen, A.F.W. (author), Gijsen, F.J.H. (author)
Carotid magnetic resonance imaging (MRI) is used to noninvasively assess atherosclerotic plaque fibrous cap (FC) status, which is closely related to ischemic stroke. Acquiring anisotropic voxels improves in-plane visualization, however, an oblique scan plane orientation could then obscure a FC (i.e., contrast below the noise level) and thus...
journal article 2014
document
Jansen, K. (author), Van Soest, G. (author), Van der Steen, A.F.W. (author)
The vulnerable atherosclerotic plaque is believed to be at the root of the majority of acute coronary events. Even though the exact origins of plaque vulnerability remain elusive, the thin-cap fibroatheroma, characterized by a lipid-rich necrotic core covered by a thin fibrous cap, is considered to be the most prominent type of vulnerable plaque...
journal article 2014
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Jansen, K. (author), Wu, M. (author), Van der Steen, A.F.W. (author), Van Soest, G. (author)
Spectroscopic intravascular photoacoustic imaging (sIVPA) has shown promise to detect and distinguish lipids in atherosclerotic plaques. sIVPA generally utilizes one of the two high absorption bands in the lipid absorption spectrum at 1.2 ?m and 1.7 ?m. Specific absorption signatures of various lipid compounds within the bands in either...
journal article 2014
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Jansen, K. (author), Van der Steen, A.F.W. (author), Wu, M. (author), Van Beusekom, H.M.M. (author), Springeling, G. (author), Li, X. (author), Zhou, Q. (author), Shung, K.K. (author), De Kleijn, D.P.V. (author), Van Soest, G. (author)
The natural history of atherosclerosis is marked by changes in the lipid biochemistry in the diseased arterial wall. As lesions become more vulnerable, different cholesterol species accumulate in the plaque. Understanding unstable atherosclerosis as a pharmacological and interventional therapeutic target requires chemically specific imaging of...
journal article 2014
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Bulelzai, M.A.K. (author)
Atherosclerosis is a disease in which low density lipoproteins (LDL) accumulate in the arterial wall due to an inflammatory response, which is triggered by the oxidation of LDL molecules that are already present in the arterial wall. Progression of atherosclerotic plaques involves many components which includes, macrophages, monocytes, LDL,...
doctoral thesis 2013
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Carvalho, D.D.B. (author), Klein, S. (author), Akkus, Z. (author), Ten Kate, G.L. (author), Schinkel, A.F.L. (author), Bosch, J.G. (author), Van der Lugt, A. (author), Niessen, W.J. (author)
Purpose The purpose of this paper is to present a methodology to estimate the carotid artery lumen centerlines in ultrasound (US) images obtained in a free-hand examination. Challenging aspects here are speckle noise in US images, artifacts, and the lack of contrast in the direction orthogonal to the US beam direction. Method An algorithm based...
journal article 2011
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Van Engelen, A. (author), De Bruijne, M. (author), Klein, S. (author), Verhagen, H. (author), Groen, H. (author), Wentzel, J. (author), Van der Ligt, A. (author), Niessen, W. (author)
Automatic quantification of carotid artery plaque composition is important in the development of methods that distinguish vulnerable from stable plaques. MRI has shown to be capable of imaging different components noninvasively. We present a new plaque classification method which uses 3D registration of histology data with ex vivo MRI data,...
conference paper 2011
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Haverkort, J.W. (author), Kenjereš, S. (author)
A comprehensive computational model for simulating magnetic drug targeting was developed and extensively tested in a cylindrical geometry. The efficiency for particle capture in a specific magnetic field and geometry was shown to be dependent on a single dimensionless number. The effect of secondary flows, a non-Newtonian viscosity and...
conference paper 2009
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Vennemann, P. (author)
The development, the regulation, and the pathology of the circulatory system (e.g. cardiogenesis, thermoregulation, atherosclerosis) are determined by blood flow induced mechanical forces. While this proposition has been confirmed during recent years, the exact mechanisms still remain unclear. This is mainly due to the fact that those forces...
doctoral thesis 2008
Searched for: subject:"atherosclerosis"
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