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Kheybari, Siamak (author), Davoodi Monfared, Mansoor (author), Salamirad, Amirhossein (author), Rezaei, J. (author)To design a bioethanol supply chain, along with the transportation and operational costs, it is vital to consider more factors categorized into three sustainability pillars (i.e. economy, social and environment). In this paper, to develop a mathematical model for bioethanol supply chain (BSC), we propose a two-phase methodology; in the first...journal article 2023
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Jankovic, T.J. (author), Straathof, Adrie J.J. (author), Kiss, A.A. (author)Syngas fermentation is used industrially to produce diluted bioethanol (about 1–6 wt%). This research study proposes a novel downstream process that recovers bioethanol in an energy-efficient and cost-effective manner, improves fermentation yield by recycling all fermentation broth components (microbes, acetate and water), and is designed for...journal article 2023
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van Aalst, A.C.A. (author), van der Meulen, Igor S. (author), Jansen, Mickel L.A. (author), Mans, R. (author), Pronk, J.T. (author)Glycerol is the major organic byproduct of industrial ethanol production with the yeast Saccharomyces cerevisiae. Improved ethanol yields have been achieved with engineered S. cerevisiae strains in which heterologous pathways replace glycerol formation as the predominant mechanism for anaerobic re-oxidation of surplus NADH generated in...journal article 2023
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de Valk, S.C. (author), Bouwmeester, Susan E. (author), de Hulster, A.F. (author), Mans, R. (author)Background: In the yeast Saccharomyces cerevisiae, which is widely applied for industrial bioethanol production, uptake of hexoses is mediated by transporters with a facilitated diffusion mechanism. In anaerobic cultures, a higher ethanol yield can be achieved when transport of hexoses is proton-coupled, because of the lower net ATP yield of...journal article 2022
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Magalhaes de Medeiros, E. (author), Noorman, H.J. (author), Filho, Rubens Maciel (author), Posada Duque, J.A. (author)This work presents a strategy for optimizing the production process of ethanol via integrated gasification and syngas fermentation, a conversion platform of growing interest for its contribution to carbon recycling. The objective functions (minimum ethanol selling price (MESP), energy efficiency, and carbon footprint) were evaluated for the...journal article 2021
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Jaspers, B. C. (author), Kuo, P.C. (author), Amladi, Amogh (author), van Neerbos, Wouter (author), Aravind, P.V. (author)Negative emission technologies have recently received increasing attention due to climate change and global warming. One among them is bioenergy with carbon capture and storage (BECCS), but the capture process is very energy intensive. Here, a novel pathway is introduced, based on second-generation biofuels followed by carbon circulation in...journal article 2021
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Kheybari, Siamak (author), Javdanmehr, Mahsa (author), Rezaie, Fariba Mahdi (author), Rezaei, J. (author)The purpose of this paper is to streamline the supply of corn, one of the key ingredients in the production of bioethanol. Using a comprehensive sustainable framework of criteria (including social, economic, and environmental dimensions), the potential locations of corn cultivation in Iran are examined from a multi-criteria decision analysis...journal article 2021
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Magalhaes de Medeiros, E. (author), Noorman, H.J. (author), Maciel Filho, Rubens (author), Posada Duque, J.A. (author)In this work, a model was developed to predict the performance of a bubble column reactor for syngas fermentation and the subsequent recovery of anhydrous ethanol. The model was embedded in an optimization framework which employs surrogate models (artificial neural networks) and multi-objective genetic algorithm to optimize different process...journal article 2020
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Echaroj, Snunkhaem (author), Ong, Hwai Chyuan (author), Chen, X. (author)Bioethanol synthesis techniques have been studied intensively due to the energy crisis and various environmental concerns. A two-step bioethanol production process was carried out multiple times in an unbaffled agitator tank. The parameters varied, including the fermentation temperature, the pH level, the amount of yeast, and the impeller type....journal article 2020
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Pabon-Pereira, Claudia (author), Slingerland, Maja (author), Hogervorst, Sanna (author), van Lier, J.B. (author), Rabbinge, Rudy (author)This paper shows how system design determines sustainability outcomes of cassava bioethanol production in Colombia. The recovery of the energy contained in by-products is recommended as compared to single product production. In particular, this study assesses the energy, greenhouse gases, water, and land use performance of alternative cassava...journal article 2019
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Kheybari, S. (author), Kazemi, Mostafa (author), Rezaei, J. (author)One of the major factors in the success of renewable energy is finding a proper location for production facilities. At a national level, different parts of a country (e.g. provinces) can be seen as alternatives that can be assessed based on a set of criteria, and ranking them to identify the best location. The focus in this paper is on...journal article 2019
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Bracher, J.M. (author), Verhoeven, M.D. (author), Wisselink, H. Wouter (author), Crimi, B. (author), Nijland, Jeroen G. (author), Driessen, Arnold J.M. (author), Klaassen, Paul (author), van Maris, A.J.A. (author), Daran, J.G. (author), Pronk, J.T. (author)Background: l-Arabinose occurs at economically relevant levels in lignocellulosic hydrolysates. Its low-affinity uptake via the Saccharomyces cerevisiae Gal2 galactose transporter is inhibited by d-glucose. Especially at low concentrations of l-arabinose, uptake is an important rate-controlling step in the complete conversion of these...journal article 2018
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Verhoeven, M.D. (author), de Valk, S.C. (author), Daran, J.G. (author), van Maris, A.J.A. (author), Pronk, J.T. (author)D-Glucose, D-xylose and L-arabinose are major sugars in lignocellulosic hydrolysates. This study explores fermentation of glucose-xylose-arabinose mixtures by a consortium of three ‘specialist’ Saccharomyces cerevisiae strains. A D-glucose- and L-arabinose-tolerant xylose specialist was constructed by eliminating hexose phosphorylation in an...journal article 2018
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Verhoeven, M.D. (author), Bracher, J.M. (author), Nijland, Jeroen G. (author), Bouwknegt, J. (author), Daran, J.G. (author), Driessen, Arnold J.M. (author)Cas9-assisted genome editing was used to construct an engineered glucose-phosphorylation-negative S. cerevisiae strain, expressing the Lactobacillus plantaruml-arabinose pathway and the Penicillium chrysogenum transporter PcAraT. This strain, which showed a growth rate of 0.26 h−1 on l-arabinose in aerobic batch cultures, was subsequently...journal article 2018
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Papapetridis, I. (author), van Dijk, M. (author), van Maris, A.J.A. (author), Pronk, J.T. (author)Background: Glycerol, whose formation contributes to cellular redox balancing and osmoregulation in Saccharomyces cerevisiae, is an important by-product of yeast-based bioethanol production. Replacing the glycerol pathway by an engineered pathway for NAD<sup>+</sup>-dependent acetate reduction has been shown to improve ethanol yields and...journal article 2017
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Fakkert, S.C.M. (author)Within the context of growing concerns about oil supply security and greenhouse gas emissions, both the aviation and petrochemical sector are exploring alternative feedstocks for the production of jet fuel and chemicals, respectively. In that light, research into bio-based jet fuels (biojet fuel) and bio-based chemicals has been accelerating in...master thesis 2016
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Gonzalez Ramos, D. (author), Gorter de Vries, A.R. (author), Grijseels, Sietske S. (author), van Berkum, M.C. (author), Swinnen, Steve (author), van den Broek, M.A. (author), Nevoigt, Elke (author), Daran, J.G. (author), Pronk, J.T. (author), van Maris, A.J.A. (author)Background: Acetic acid, released during hydrolysis of lignocellulosic feedstocks for second generation bioethanol production, inhibits yeast growth and alcoholic fermentation. Yeast biomass generated in a propagation step that precedes ethanol production should therefore express a high and constitutive level of acetic acid tolerance before...journal article 2016
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Dereli, R.K. (author)The success of anaerobic digestion relies on the presence of highly active methanogenic biomass, requiring effective retention of slow growing anaerobic microorganisms inside bioreactor by decoupling the hydraulic retention time (HRT) from solids residence time (SRT) or the employment of long SRTs in fully mixed systems. So far, flow through...doctoral thesis 2015
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Huisjes, E.H. (author)The ambition to reduce our current dependence on fossil transportation fuels has driven renewed interest in bioethanol. Pectin-rich feedstocks like sugar beet pulp and citrus peel, which are currently sold as cattle feed, are promising raw materials for the production of bioethanol. This thesis explores the challenges related to the fermentation...doctoral thesis 2013
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Guadalupe-Medina, V. (author), Wisselink, H.W. (author), Luttik, M.A.H. (author), De Hulster, E. (author), Daran, J.M. (author), Pronk, J.T. (author), Van Maris, A.J.A. (author)Background Redox-cofactor balancing constrains product yields in anaerobic fermentation processes. This challenge is exemplified by the formation of glycerol as major by-product in yeast-based bioethanol production, which is a direct consequence of the need to reoxidize excess NADH and causes a loss of conversion efficiency. Enabling the use of...journal article 2013
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