Using the Multiple Instance Learning framework to address differential regulation

Cell differentiation is a natural process occurring in all higher organisms, since the early fetal stage of life. It is, also, a part of disease – such as cancer – as the cell cycle becomes deregulated and cells behave differently compared to healthy ones. Differentiation occurs although the genome of all cells is identical across all cell types...

Finding cancer genes in copy number data and insertional mutagenesis data

Cancer is a genetic disease. Step-wise alteration of genes that have a normal function in the cell can lead to the transformation of a healthy cell into a malignant cancer cell. Cancer genes provide several traits to the cell that allow it to become malignant. These traits have been researched for many years, and currently one knows quite well...