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Puiman, L. (author)One of the major challenges mankind faces nowadays is combating climate change. A substantial fraction of greenhouse gases are released by industrial processes, as steelmaking, (oil)refinery and waste processing. Emissions from these processes can partly be prevented with a recently developed technology called gas fermentation. Within this...doctoral thesis 2024
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Volger, R. (author), Puiman, L. (author), Haringa, C. (author)The growing global population and heightened concern for climate change leads to increased interest in utilizing microbial fermentations to replace polluting production processes for e.g., plastics, fuels, and animal proteins. Computational fluid dynamics (CFD) is a valuable tool for accelerating the scale-up and optimization of large-scale...review 2024
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Rahimi, Zahra (author), Zinatizadeh, Ali Akbar (author), Zinadini, Sirus (author), van Loosdrecht, Mark C.M. (author), JBatstone, Damien (author)In this work, a one-stage dual internal circulation airlift anaerobic/anoxic/aerobic (DCAL-A2O) bioreactor was continuously operated for concurrent removal of nutrients and organics from milk processing wastewater (MPW). Special configuration of the airlift A2O bioreactor created possibility of the formation of desired anaerobic, anoxic and...journal article 2024
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Gallego Murillo, Joan Sebastián (author)Production of cultured red blood cells (cRBCs) hold the promise of being a potentially unlimited source of cells that could cover the increasing demand of RBCs for transfusion purposes, while having more control on the quality and safety of the cells compared to the current donor-dependent system. cRBCs could also be used for novel therapies in...doctoral thesis 2023
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Zha, Qinying (author)Driven by the increasing demand for waste reduction and green energy production, an integrated system which combines an anaerobic membrane bioreactor (AnMBR) and a solid oxide fuel cell (SOFC) was proposed in this research project for blackwater treatment and energy production. The potentials of using an AnMBR for wastewater treatment and biogas...master thesis 2023
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Waling, Loulotte (author)In recent years, biotechnological processes have gained increased interest due to their potential for high-value compound production and waste recycling. This shift towards biotechnology is driven by global challenges such as food security, climate change, and the transition to renewable resources. To address the limitations of large-scale...master thesis 2023
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Eijsberg, Daan (author)Fermentation processes are considered to be essential to decrease our reliance on fossil fuel based products. However, the scale-up from lab-scale to industrial-scale has proven to be difficult. Computational Fluid Dynamics (CFD) has the potential to be a tool to optimize the scale-up and to help engineers understand the relevant hydrodynamics...master thesis 2023
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Blöbaum, Luisa (author), Haringa, C. (author), Grünberger, Alexander (author)Bioprocesses are scaled up for the production of large product quantities. With larger fermenter volumes, mixing becomes increasingly inefficient and environmental gradients get more prominent than in smaller scales. Environmental gradients have an impact on the microorganism's metabolism, which makes the prediction of large-scale performance...review 2023
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Piaggio, A.L. (author), Sasidhar, K.B. (author), Khande, Pravin (author), Balakrishnan, Malini (author), van Lier, J.B. (author), de Kreuk, M.K. (author), Lindeboom, R.E.F. (author)This study reports the effects of microaeration on a laboratory-scale AnMBR (MA-AnMBR) fed with synthetic concentrated domestic sewage. The imposed oxygen load mimics the oxygen load coming from a dissolved air flotation (DAF) unit, establishing an anaerobic digester-DAF (AD-DAF) combination with sludge recycling. Results showed a reduced COD...journal article 2023
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Li, Y. (author), Pavanram, P. (author), Bühring, J. (author), Rütten, S. (author), Schröder, K. U. (author), Zhou, J. (author), Pufe, T. (author), Wang, L. . (author), Zadpoor, A.A. (author), Jahr, H. (author)Additively manufactured (AM) degradable porous metallic biomaterials offer unique opportunities for satisfying the design requirements of an ideal bone substitute. Among the currently available biodegradable metals, iron has the highest elastic modulus, meaning that it would benefit the most from porous design. Given the successful...journal article 2023
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Winkelhorst, O.M. (author), Cabau Peinado, O. (author), Straathof, Adrie J.J. (author), Jourdin, L. (author)Microbial electrochemical technologies (METs) employ microorganisms utilizing solid-state electrodes as either electron sink or electron source, such as in microbial electrosynthesis (MES). METs reaction rate is traditionally normalized to the electrode dimensions or to the electrolyte volume, but should also be normalized to biomass amount...journal article 2023
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Minden, Steven (author), Aniolek, Maria (author), Noorman, H.J. (author), Takors, Ralf (author)Commercial-scale bioreactors create an unnatural environment for microbes from an evolutionary point of view. Mixing insufficiencies expose individual cells to fluctuating nutrient concentrations on a second-to-minute scale while transcriptional and translational capacities limit the microbial adaptation time from minutes to hours. This...journal article 2023
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Puiman, L. (author), Almeida Benalcazar, E.F. (author), Picioreanu, C. (author), Noorman, H.J. (author), Haringa, C. (author)In large-scale syngas fermentation, strong gradients in dissolved gas (CO, H<sub>2</sub>) concentrations are very likely to occur due to locally varying mass transfer and convection rates. Using Euler-Lagrangian CFD simulations, we analyzed these gradients in an industrial-scale external-loop gas-lift reactor (EL-GLR) for a wide range of...journal article 2023
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Ek, Sovannmonica (author)Pulp and paper industries are water-intensive industries and composed of complex production processes. Untreated pulping wastewater is very toxic and lethal to aquatic life if discharged untreated. Anaerobic treatment technology has gained interest in treating these types of wastewater by reducing organic compounds. This thesis research aimed to...master thesis 2022
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Zha, Qinying (author)Palm oil is a popular ingredient in domestic products. The palm oil industry has been growing rapidly over the past decades, so that the amount of palm oil mill effluent (POME) generated from the palm oil production has been increasing as well. The anaerobic membrane bioreactor (AnMBR) is a treatment solution that can remove organic pollutants...student report 2022
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Odriozola, Magela (author)Anaerobic membrane bioreactor (AnMBR) technology is increasingly researched for wastewater treatment in a circular economy scenario to recover nutrients, water, and biogas. AnMBR couples the advantages of anaerobic digestion, such as low sludge production, no aeration requirement and biogas production, with the benefits of membrane technology,...doctoral thesis 2022
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Lip, K.Y.F. (author)Saccharomyces yeasts are common workhorses for the production of alcoholic beverage and bio-ethanol. In these production processes, temperature is one of the predominant factors determining the operational costs of the industrial fermentation processes and the quality of the products (alcoholic beverage) because it influences the functioning of...doctoral thesis 2022
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Szabo Corbacho, M. (author), Pacheco-Ruiz, Santiago (author), Míguez, Diana (author), Hooijmans, Christine Maria (author), Brdjanovic, Damir (author), Garcia, Hector A. (author), van Lier, J.B. (author)This study evaluated the effects of sludge retention time (SRT) on the membrane filtration performance of an anaerobic membrane bioreactor (AnMBR) fed lipid-rich synthetic dairy wastewater. The membrane filtration performance was evaluated in two AnMBR systems operated at two different SRTs, i.e., 20 and 40 days. For the AnMBR operated at 40...journal article 2022
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Odriozola, Magela (author), van Lier, J.B. (author), Spanjers, H. (author)Flux enhancers (FEs) have been successfully applied for fouling mitigation in membrane bioreactors. However, more research is needed to compare and optimise different dosing strategies to improve the filtration performance, while minimising the use of FEs and preventing overdosing. Therefore, the goal of this research is to develop an...journal article 2022
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Holohan, B. Conall (author), Duarte, M. Salomé (author), Szabo Corbacho, M. (author), Cavaleiro, Ana J. (author), Salvador, Andreia F. (author), Pereira, M. Alcina (author), Ziels, Ryan M. (author), Frijters, Carla T.M.J. (author), van Lier, J.B. (author)Several problems associated with the presence of lipids in wastewater treatment plants are usually overcome by removing them ahead of the biological treatment. However, because of their high energy content, waste lipids are interesting yet challenging pollutants in anaerobic wastewater treatment and codigestion processes. The maximal amount...review 2022