Searched for: subject:"disorder"
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Hartanto, D. (author)
Social anxiety disorder (SAD), commonly referred to social phobia, is one of the most an immense and unreasonable fear of social interaction. Cognitive behaviour therapy (CBT) is the most thoroughly studied nonpharmacologic approach to the treatment of SAD patients. In CBT, patients are gradually, in <i>vivo</i>, exposed to anxiety-provoking...
doctoral thesis 2019
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Burbach, Peter P.H. (author), Meijer, D.H.M. (author)
Latrophilins (LPHNs) are adhesion GPCRs that are originally discovered as spider’s toxin receptors, but are now known to be involved in brain development and linked to several neuronal and non-neuronal disorders. Latrophilins act in conjunction with other cell adhesion molecules and may play a leading role in its network organization. Here,...
review 2019
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Knol, Maria J. (author), Heshmatollah, Alis (author), Cremers, Lotte G M (author), Ikram, Mohammad K. (author), Uitterlinden, André G. (author), van Duijn, Cornelia M. (author), Niessen, W.J. (author), Vernooij, Meike W. (author), Ikram, Mohammad Arfan (author), Adams, Hieab H.H. (author)
Cognition in adults shows variation due to developmental and degenerative components. A recent genome-wide association study identified genetic variants for general cognitive function in 148 independent loci. Here, we aimed to elucidate possible developmental and neurodegenerative pathways underlying these genetic variants by relating them to...
journal article 2019
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Tielman, M.L. (author)
Post-traumatic stress disorder (PTSD) is a mental disorder with a high impact on quality of life, and despite the existence of treatment, barriers still stop many people from receiving the care they need. An e-mental health system for home use might remove some of these barriers, as it provides a privacy-sensitive and accessible way of following...
doctoral thesis 2018
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Tielman, M.L. (author), Neerincx, M.A. (author), Bidarra, Rafael (author), Kybartas, B.A. (author), Brinkman, W.P. (author)
Although post-traumatic stress disorder (PTSD) is well treatable, many people do not get the desired treatment due to barriers to care (such as stigma and cost). This paper presents a system that bridges this gap by enabling patients to follow therapy at home. A therapist is only involved remotely, to monitor progress and serve as a safety...
journal article 2017
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Doorenweerd, Nathalie (author), Mahfouz, A.M.E.T.A. (author), van Putten, Maaike (author), Kaliyaperumal, Rajaram (author), 't Hoen, P.A.C. (author), Hendriksen, Jos G.M. (author), Aartsma-Rus, Annemieke M. (author), Verschuuren, Jan J.G.M. (author), Niks, Erik H. (author), Reinders, M.J.T. (author), Kan, Hermien E. (author), Lelieveldt, B.P.F. (author)
Duchenne muscular dystrophy (DMD) is a muscular dystrophy with high incidence of learning and behavioural problems and is associated with neurodevelopmental disorders. To gain more insights into the role of dystrophin in this cognitive phenotype, we performed a comprehensive analysis of the expression patterns of dystrophin isoforms across...
journal article 2017
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Merlen, A. (author), Buijnsters, J.G. (author), Pardanaud, C. (author)
sp2 hybridized carbons constitute a broad class of solid phases composed primarily of elemental carbon and can be either synthetic or naturally occurring. Some examples are graphite, chars, soot, graphene, carbon nanotubes, pyrolytic carbon, and diamond-like carbon. They vary from highly ordered to completely disordered solids and detailed...
journal article 2017
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Yagob Mohamed, T.I. (author)
Iron is an essential trace element involved in many processes in the human body. Some disorders like iron deficiency anaemia and haemochromatosis directly result from changes in iron status, while on the other hand iron metabolism changes during illness. Since these adjustments in the iron handling of the body may have consequences for the...
doctoral thesis 2016
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Collet, F. (author), Ruszel, W.M. (author)
We characterize the phase space for the infinite volume limit of a ferromagnetic mean-field XY model in a random field pointing in one direction with two symmetric values. We determine the stationary solutions and detect possible phase transitions in the interaction strength for fixed random field intensity. We show that at low temperature...
journal article 2016
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Favié, Joris (author), Ghazi Vakili, V. (author), Brinkman, W.P. (author), Morina, N (author), Neerincx, M.A. (author)
Certain professions carry a risk of experiencing traumatic events and sometimes developing Posttraumatic Stress Disorder (PTSD). Researchers have been working on strategies to prevent professionals in those fields from developing PTSD. Recently, there has been a focus on applying technology that supports these preventive strategies, especially...
book chapter 2016
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Yin, L.J. (author), Ji, Wei Wei (author), Liu, Shi Yu (author), He, Wei Dong (author), Zhao, Lin (author), Xu, Xin (author), Fabre, A. (author), Dierre, B.F.P.R. (author), Lee, Ming Hsien (author), van Ommen, J.R. (author), Hintzen, H.T.J.M. (author)
Synthesizing pure phase Ba<sub>3</sub>Si<sub>6</sub>O<sub>9</sub>N<sub>4</sub> by the conventional solid-state reaction method is challenging because of easily formed secondary phase Ba<sub>3</sub>Si<sub>6</sub>O<sub>12</sub>N<sub>2</sub> showing similar crystal structure. In this work, an alternative low temperature synthesis method is...
journal article 2016
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Mahfouz, A. (author), Ziats, M.N. (author), Rennert, O.M. (author), Lelieveldt, B.P.F. (author), Reinders, M.J.T. (author)
Autism spectrum disorder (ASD) is a neurodevelopmental syndrome known to have a significant but complex genetic etiology. Hundreds of diverse genes have been implicated in ASD; yet understanding how many genes, each with disparate function, can all be linked to a single clinical phenotype remains unclear. We hypothesized that understanding...
journal article 2015
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Meskers, C.G.M. (author), De Groot, J. (author), De Vlugt, E. (author), Schouten, A.C. (author)
Progress in diagnosis and treatment of movement disorders after neurological diseases like stroke, cerebral palsy (CP), dystonia and at old age requires understanding of the altered capacity to adequately respond to physical obstacles in the environment. With posture and movement disorders, the control of muscles is hampered, resulting in...
journal article 2015
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Dekker, M.C. (author), Van Lochem, A.J. (author), Molenbroek, J.F.M. (author)
A healthy work-to-rest ratio during computer work can be an important part of successful preventive workrelated upper limb disorders (WRULD) intervention. Existing break software applications designed to realise such a work-to-rest ratio often possess product features that limit their functionality. Most applications focus on physical relaxation...
journal article 2015
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Coumou, P.C.J.J. (author)
Thin films of superconducting materials with a high resistance in the normal state, such as TiN, NbTiN, NbN and InO, are intensively studied from both an application and a fundamental point of view. A spatially inhomogeneous superconducting state can arise in these materials as a result of the strong disorder. This Thesis provides an...
doctoral thesis 2015
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Bluyssen, P.M. (author)
conference paper 2014
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De Gooijer-van de Groep, K.L. (author), De Vlugt, E. (author), De Groot, J.H. (author), Van der Heijden-Maessen, H.C.M. (author), Wielheesen, D.H.M. (author), Van Wijlen-Hempel, R.M.S. (author), Arendzen, J.H. (author), Meskers, C.G.M. (author)
Background Spastic paresis in cerebral palsy (CP) is characterized by increased joint stiffness that may be of neural origin, i.e. improper muscle activation caused by e.g. hyperreflexia or non-neural origin, i.e. altered tissue viscoelastic properties (clinically: “spasticity” vs. “contracture”). Differentiation between these components is hard...
journal article 2013
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Maresca, D. (author), Jansen, K. (author), Renaud, G. (author), Van Soest, G. (author), Li, X. (author), Zhou, Q. (author), De Jong, N. (author), Shung, K.K. (author), Van der Steen, A.F.W. (author)
We demonstrate the feasibility of intravascular ultrasound (IVUS) chirp imaging as well as chirp reversal ultrasound contrast imaging at intravascular ultrasound frequency. Chirp excitations were emitted with a 34?MHz single crystal intravascular transducer and compared to conventional Gaussian-shaped pulses of equal acoustic pressure. The...
journal article 2012
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Mugge, W. (author)
Complex Regional Pain Syndrome (CRPS) is a disabling syndrome associated with sensory (e.g., burning pain, allodynia, hyperalgesia), autonomic (e.g., edema, skin color and temperature changes), and motor impairments (e.g., tremor, myoclonus, dystonia). Approximately 25% of the patients with CRPS develop fixed dystonia which is characterized by...
doctoral thesis 2011
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Li, B. (author), Guo, W. (author), Blöte, H.W.J. (author)
A critical dilute O(n) model on the kagome lattice is investigated analytically and numerically. We employ a number of exact equivalences which, in a few steps, link the critical O(n) spin model on the kagome lattice to the exactly solvable critical q-state Potts model on the honeycomb lattice with q=(n+1)². The intermediate steps involve the...
journal article 2008
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