Searched for: subject:"evolution"
(1 - 20 of 103)

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Price, Claire E. (author), Branco Dos Santos, Filipe (author), Hesseling, Anne (author), Uusitalo, Jaakko J. (author), Bachmann, Herwig (author), Benavente, Vera (author), Goel, A. (author), Berkhout, Jan (author), More Authors (author)
Background: A central theme in (micro)biology is understanding the molecular basis of fitness i.e. which strategies are successful under which conditions; how do organisms implement such strategies at the molecular level; and which constraints shape the trade-offs between alternative strategies. Highly standardized microbial laboratory...
journal article 2019
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Zhu, Jianbo (author), Fang, Miao (author), Shi, Q. (author), Wang, Peng (author), Li, Qian (author)
The large scale of construction in mega projects leads to significant environmental and socioeconomic impacts; thus, the projects should also exhibit greater social responsibility. Adopting green supply chain management in the construction process is an important way to realize the goal of sustainable development of mega projects. Because the...
journal article 2018
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van Toorenenburg, K.A. (author)
A generic life cycle applies to crevasse splays in non-degradational fluvial systems, typically ending in healing and abandonment. Crevasse-splay channels adjust to a graded equilibrium profile through proximal erosion and distal deposition, with their distal termini acting as a (prograding) local base level. When proximal incision advances to...
doctoral thesis 2018
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Verhoeven, M.D. (author), Bracher, J.M. (author), Nijland, Jeroen G. (author), Bouwknegt, J. (author), Daran, J.G. (author), Driessen, Arnold J.M. (author)
Cas9-assisted genome editing was used to construct an engineered glucose-phosphorylation-negative S. cerevisiae strain, expressing the Lactobacillus plantaruml-arabinose pathway and the Penicillium chrysogenum transporter PcAraT. This strain, which showed a growth rate of 0.26 h−1 on l-arabinose in aerobic batch cultures, was subsequently...
journal article 2018
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Zhao, Jie (author), Guo, Leicheng (author), He, Qing (author), Wang, Zhengbing (author), van Maren, D.S. (author), Wang, X. (author)
Examination of large scale, alluvial estuarine morphology and associated time evolution is of particular importance regarding management of channel navigability, ecosystem, etc. In this work, we analyze morphological evolution and changes of the channel-shoal system in the Changjiang Estuary, a river- and tide-controlled coastal plain estuary,...
journal article 2018
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Kuo, Feng-Wei (author), Babaie, M. (author), Chen, Huan-Neng (Ron) (author), Cho, Lan-Chou (author), Jou, Chewn-Pu (author), Chen, Mark (author), Staszewski, R.B. (author)
We propose a time-predictive architecture of an all-digital PLL (ADPLL) for cellular radios, which is optimized for advanced CMOS. It is based on a 1/8-length time-to-digital converter (TDC) of stabilized 7-ps resolution, as well as wide tuning range, and fine-resolution class-F digitally controlled oscillator (DCO) with only switchable metal...
journal article 2018
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Marques, W.L. (author), van der Woude, L.N. (author), Luttik, M.A.H. (author), van den Broek, M.A. (author), Pronk, J.T. (author), van Maris, A.J.A. (author), Mans, R. (author), Gombert, Andreas K. (author)
Knowledge on the genetic factors important for the efficient expression of plant transporters in yeast is still very limited. Phaseolus vulgaris sucrose facilitator 1 (PvSuf1), a presumable uniporter, was an essential component in a previously published strategy aimed at increasing ATP yield in Saccharomyces cerevisiae. However, attempts to...
journal article 2018
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Diepeveen, E.T. (author), Gehrmann, T. (author), Abeel, T.E.P.M.F. (author), Pourquié, Valérie (author), Laan, L. (author)
The combined actions of proteins in networks underlie all fundamental cellular functions. Deeper insights into the dynamics of network composition across species and their functional consequences are crucial to fully understand protein network evolution. Large-scale comparative studieswith high phylogenetic resolution arenowfeasible through...
journal article 2018
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Gomez De Santos, Patricia (author), Cañellas, Marina (author), Tieves, F. (author), Younes, S.H.H. (author), Molina-Espeja, Patricia (author), Hofrichter, Martin (author), Hollmann, F. (author), Guallar, Victor (author), Alcalde, Miguel (author)
Propranolol is a widely used beta-blocker that is metabolized by human liver P450 monooxygenases into equipotent hydroxylated human drug metabolites (HDMs). It is paramount for the pharmaceutical industry to evaluate the toxicity and activity of these metabolites, but unfortunately, their synthesis has hitherto involved the use of severe...
journal article 2018
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Jetten, L. (author), van Iersel, L.J.J. (author)
Rooted phylogenetic networks are used to describe evolutionary histories that contain non-treelike evolutionary events such as hybridization and horizontal gene transfer. In some cases, such histories can be described by a phylogenetic base-tree with additional linking arcs, which can for example represent gene transfer events. Such phylogenetic...
journal article 2018
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de Angelis, L. (author), Alpeggiani, F. (author), Di Falco, Andrea (author), Kuipers, L. (author)
Phase singularities are locations where light is twisted like a corkscrew, with positive or negative topological charge depending on the twisting direction. Among the multitude of singularities arising in random wave fields, some can be found at the same location, but only when they exhibit opposite topological charge, which results in their...
journal article 2017
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Martínez, Angel T. (author), Ruiz-Dueñas, Francisco J. (author), Camarero, Susana (author), Serrano, Ana (author), Linde, Dolores (author), Lund, Henrik (author), Vind, Jesper (author), Tovborg, Morten (author), Herold-Majumdar, Owik M. (author), Hofrichter, Martin (author), Liers, Christiane (author), Ullrich, René (author), Scheibner, Katrin (author), Sannia, Giovanni (author), Piscitelli, Alessandra (author), Pezzella, Cinzia (author), Sener, Mehmet E. (author), Kılıç, Sibel (author), van Berkel, Willem J.H. (author), Guallar, Victor (author), Lucas, Maria Fátima (author), Zuhse, Ralf (author), Ludwig, Roland (author), Hollmann, F. (author), Fernandez Fueyo, E. (author), Record, Eric (author), Faulds, Craig B. (author), Tortajada, Marta (author), Winckelmann, Ib (author), Rasmussen, Jo Anne (author), Gelo-Pujic, Mirjana (author), Gutiérrez, Ana (author), del Río, José C. (author), Rencoret, Jorge (author), Alcalde, Miguel (author)
Fungi produce heme-containing peroxidases and peroxygenases, flavin-containing oxidases and dehydrogenases, and different copper-containing oxidoreductases involved in the biodegradation of lignin and other recalcitrant compounds. Heme peroxidases comprise the classical ligninolytic peroxidases and the new dye-decolorizing peroxidases, while...
review 2017
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Bruell, G. (author), Ehrnström, Mats (author), Geyer, A. (author), Pei, Long (author)
We show that for a large class of evolutionary nonlinear and nonlocal partial differential equations, symmetry of solutions implies very restrictive properties of the solutions and symmetry axes. These restrictions are formulated in terms of three principles, based on the structure of the equations. The first principle covers equations that...
journal article 2017
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Bracher, J.M. (author), de Hulster, A.F. (author), van den Broek, M.A. (author), Daran, J.G. (author), van Maris, A.J.A. (author), Pronk, J.T. (author)
Biotin prototrophy is a rare, incompletely understood, and industrially relevant characteristic of Saccharomyces cerevisiae strains. The genome of the haploid laboratory strain CEN.PK113-7D contains a full complement of biotin biosynthesis genes, but its growth in biotin-free synthetic medium is extremely slow (specific growth rate [μ] ≈ 0.01...
journal article 2017
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Diepeveen, E.T. (author), Iñigo de la Cruz, L.M. (author), Laan, L. (author)
Polarity establishment underlies proper cell cycle completion across virtually all organisms. Much progress has been made in generating an understanding of the structural and functional components of this process, especially in model species. Here we focus on the evolutionary dynamics of the fungal polarization protein network in order to...
review 2017
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Dintzner, N.J.R. (author)
Most modern software systems can be adjusted to satisfy sets of conflicting requirements issued by different groups of users, based on their intended usage or execution context. For systems where configurations are a core concern, specific implementation mechanisms are put in place to allow the instantiation of sets of tailored components. Among...
doctoral thesis 2017
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Flohr, R.C.E. (author)
doctoral thesis 2017
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Cats, O. (author)
The structure of transport networks is the outcome of a large number of infrastructure investment decisions taken over a long time span. Network indicators are widely used for characterizing transport network topology and its performance as well as provide insights on possible developments. Little is known however on how rail bound public...
journal article 2017
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Lange, K.P.H. (author), Korevaar, G. (author), Oskam, Inge F. (author), Herder, P.M. (author)
Symbiotic Urban Agriculture Networks (SUANs) are a specific class of symbiotic networks that intend to close material and energy loops from cities and urban agriculture. Private and public stakeholders in SUANs face difficulties in the implementation of technological and organisational design interventions due to the complex nature of the...
journal article 2017
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van Iersel, L.J.J. (author), Moulton, V.L. (author), de Swart, Eveline (author), Wu, Taoyang (author)
Phylogenetic networks are a generalization of evolutionary trees that are used by biologists to represent the evolution of organisms which have undergone reticulate evolution. Essentially, a phylogenetic network is a directed acyclic graph having a unique root in which the leaves are labelled by a given set of species. Recently, some...
journal article 2017
Searched for: subject:"evolution"
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