Searched for: subject%3A%22metabolic%255C%2Bnetworks%22
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Winterbach, W. (author), Wang, H. (author), Reinders, M. (author), Van Mieghem, P. (author), De Ridder, D. (author)
Biological networks exhibit intriguing topological properties such as small-worldness. In this paper, we investigate whether the topology of a metabolic network is related to its robustness. We do so by perturbing a metabolic system in silico, one reaction at a time and studying the correlations between growth, as predicted by flux balance...
conference paper 2010
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Heijnen, J.J. (author)
It is shown that properties of biological systems which are relevant for systems biology motivated mathematical modelling are strongly shaped by general thermodynamic principles such as osmotic limit, Gibbs energy dissipation, near equilibria and thermodynamic driving force. Each of these aspects will be demonstrated both theoretically and...
journal article 2010
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Melia, T. (author)
As the metabolic network reconstruction process via manual curation proves to be a tedious process, the need for an automated reconstruction tool becomes imminent. There has been previous attempts to automate metabolic network reconstruction. These existing approaches rely on sequence similarity to infer functions. Consequently, they fail to...
master thesis 2009