A ground structure based topology optimization method for thermofluid problems

In this thesis, a ground structure based thermofluid topology optimization (TO) method is presented which is applicable to problems with creeping flow. Fluid channels with creeping flow are found in a variety of engineering applications, primarily in the field of microfluidics. Current fluid channel TO is typically done with density-based TO and...

Design of micro-fluidic bio-reactors

We address the design of optimal reactors for supporting biological cultures using the method of topology optimization. For some years this method have been used to design various optimal microfluidic devices [1, 2, 3, 4]. We apply this method to distribute optimally biologic cultures within a flow of nutrition. From this optimized distribution...