Searched for: subject:"microscopy"
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Agbana, T.E. (author)
Malaria remains an important cause of high morbidity and mortality worldwide. According to World Health Organisation (WHO) malaria report for 2017, malaria accounted for the death of 435,000 people. It is the leading cause of death among pregnant women and little children. 11% of maternal and 20% of under–five deaths are attributed to malaria...
doctoral thesis 2020
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Vasić, Borislav (author), Ralević, Uroš (author), Zobenica, Katarina Cvetanović (author), Smiljanić, Milče M. (author), Gajić, Radoš (author), Spasenović, Marko (author), Vollebregt, S. (author)
Chemical vapour deposition (CVD) is a promising method for producing large-scale graphene (Gr). Nevertheless, microscopic inhomogeneity of Gr grown on traditional metal substrates such as copper or nickel results in a spatial variation of Gr properties due to long wrinkles formed when the metal substrate shrinks during the cooling part of the...
journal article 2020
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Heydarian, H. (author)
Single molecule localization microscopy (SMLM) shows promise for quantitative structural analysis of subcellular complexes and organelles with a resolution well below the diffraction limit. This superresolution microscopy technique relies on the blinking events of fluorescent molecules that labeled the structure of interest and are...
doctoral thesis 2020
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Cichocka, M.O. (author), Bolhuis, M. (author), van Heijst, S.E. (author), Conesa Boj, S.C. (author)
Layered materials (LMs) such as graphene or MoS2 have attracted a great deal of interest recently. These materials offer unique functionalities due to their structural anisotropy characterized by weak van der Waals bonds along the out-of-plane axis and covalent bonds in the in-plane direction. A central requirement to access the structural...
journal article 2020
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Roobol, Stefan J. (author), Hartjes, Thomas A. (author), Slotman, Johan A. (author), de Kruijff, R.M. (author), Kanaar, R. (author), Houtsmuller, A.B. (author), Denkova, A.G. (author), van Royen, M.E. (author), Essers, J. (author)
Polymersomes have the potential to be applied in targeted alpha radionuclide therapy, while in addition preventing release of recoiling daughter isotopes. In this study, we investigated the cellular uptake, post uptake processing and intracellular localization of polymersomes. Methods: High-content microscopy was used to validate polymersome...
journal article 2020
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Santos, Luis F.P. (author), Ribeiro, Bruno (author), Hein, Luis R.O. (author), Alderliesten, R.C. (author), Zarouchas, D. (author), Botelho, Edson C. (author), Costa, Michelle L. (author)
This work concerns the fatigue behavior at three different temperature conditions (−40, 20, and 80°C) and the addition of multiwalled carbon nanotube (MWCNT) into a carbon-fiber reinforced poly(ether-imide) composite. The incorporation of MWCNT into the composite increased the tensile strength and Young's modulus by up 5 and 2%, respectively....
journal article 2020
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van Kessel, L.C.P.M. (author), Huisman, T. (author), Hagen, C.W. (author)
Line-edge roughness (LER) is often measured from top-down critical dimension scanning electron microscope (CD-SEM) images. The true three-dimensional roughness profile of the sidewall is typically ignored in such analyses. We study the response of a CD-SEM to sidewall roughness (SWR) by simulation. We generate random rough lines and spaces,...
conference paper 2020
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Wong, H.S. (author), Poole, A.B. (author), Wells, B. (author), Eden, M. (author), Barnes, R. (author), Ferrari, J. (author), Fox, R. (author), Yio, M.H.N. (author), Copuroglu, Oguzhan (author)
Water to cement (w/c) ratio is usually the most important parameter specified in concrete design and is sometimes the subject of dispute when a shortfall in concrete strength or durability is an issue. However, determination of w/c ratio in hardened concrete by testing is very difficult once the concrete has set. This paper presents the...
journal article 2020
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Zhang, Xukai (author), Ioannidou, C. (author), ten Brink, Gert H. (author), Navarro Lopez, A. (author), Wormann, Jan (author), Campaniello, Jean (author), Dalgliesh, Robert M. (author), van Well, A.A. (author), Offerman, S.E. (author), Kranendonk, Winfried (author), Kooi, Bart J. (author)
A cold-rolled Ti-V high strength low alloy (HSLA) steel was isothermally annealed at 650 °C and 700 °C for different times. A unique combination of techniques including visible light microscopy (VLM), transmission electron microscopy (TEM), matrix dissolution, small angle neutron scattering (SANS) and hardness measurement has been employed to...
journal article 2020
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Filius, M. (author), Cui, T.J. (author), Ananth, A.N. (author), Docter, M.W. (author), Hegge, Jorrit W. (author), van der Oost, John (author), Joo, C. (author)
Super-resolution imaging allows for the visualization of cellular structures on a nanoscale level. DNA-PAINT (DNA point accumulation in nanoscale topology) is a super-resolution method that depends on the binding and unbinding of DNA imager strands. The current DNA-PAINT technique suffers from slow acquisition due to the low binding rate of...
journal article 2020
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Noguera López, J. (author)
The creation of artificial cells with the minimal set of components to exhibit self-maintenance, self-reproducibility and evolvability (in other words, to be considered alive) is one of the most exciting areas within the field of synthetic biology. Such entities, here called minimal cells, are constructed by either the top-down or bottom-up...
doctoral thesis 2019
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Gong, H. (author)
This dissertation has mainly aimed at developing novel techniques, methodologies for measuring the optical field, specifically both the amplitude and phase distribution. Furthermore, we have attempted to extend their applications in the scope of optical imaging, including lensless/holographic imaging, quantitative phase imaging and the...
doctoral thesis 2019
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Kabiri, Y. (author)
The low contrast of biomolecules in TEM has been a great obstacle for their structure determination and hence to the understanding of their structure-function relation. Historically, single DNA strands remained one the most difficult classes of biomolecular specimens to image, due to low electron scattering strength of its constituent elements....
doctoral thesis 2019
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Kumar, A. (author), Saxena, A. K. (author), Kirchlechner, C. (author), Herbig, M. (author), Brinkmann, S. (author), Petrov, R.H. (author), Sietsma, J. (author)
Failure in engineering materials like steels is strongly affected by in-service deleterious alterations in their microstructure. White Etching Layers (WELs) are an example of such in-service alterations in the pearlitic microstructure at the rail surface. Cracks initiate in the rails due to delamination and fracture of these layers and...
journal article 2019
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Koiwai, Kotaro (author), Tsukimoto, Jun (author), Higashi, Tetsuya (author), Mafuné, Fumitaka (author), Miyajima, Ken (author), Nakane, Takanori (author), Matsugaki, Naohiro (author), Kato, Ryuichi (author), Jakobi, A. (author)
In cellulo crystallization is a developing technique to provide crystals for protein structure determination, particularly for proteins that are difficult to prepare by in vitro crystallization. This method has a key advantage: It requires neither a protein purification step nor a crystallization step. However, there is still no systematic...
journal article 2019
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Spaeth, Patrick (author), Adhikari, Subhasis (author), Le, Laurent (author), Jollans, Thomas (author), Pud, S. (author), Albrecht, Wiebke (author), Bauer, T.A. (author), Caldarola, M. (author), Kuipers, L. (author), Orrit, Michel (author)
Circular dichroism (CD) spectroscopy is a powerful optical technique for the study of chiral materials and molecules. It gives access to an enantioselective signal based on the differential absorption of right and left circularly polarized light, usually obtained through polarization analysis of the light transmitted through a sample of...
journal article 2019
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van den Brink, Bram (author), Alijani, F. (author), Ghatkesar, M.K. (author)
An experimental setup to perform dynamic analysis of a micro- and nano-mechanical system in vacuum, gas, and liquid is presented. The setup mainly consists of a piezoelectric excitation part and the chamber that can be either evacuated for vacuum, or filled with gas or water. The design of the piezoelectric actuator was based on a Langevin...
journal article 2019
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Leeuwenhoek, M. (author), Norte, R.A. (author), Bastiaans, Koen M. (author), Cho, Doohee (author), Battisti, Irene (author), Blanter, Y.M. (author), Groeblacher, S. (author), Allan, Milan P. (author)
We report on the fabrication and performance of a new kind of tip for scanning tunneling microscopy. By fully incorporating a metallic tip on a silicon chip using modern micromachining and nanofabrication techniques, we realize so-called smart tips and show the possibility of device-based STM tips. Contrary to conventional etched metal wire...
journal article 2019
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Beekers, D.I. (author), Lattwein, Kirby R. (author), Kouijzer, Joop J.P. (author), Langeveld, Simone A.G. (author), Vegter, M. (author), Beurskens, Robert (author), Mastik, F. (author), Verduyn Lunel, Rogier (author), van der Steen, A.F.W. (author), de Jong, N. (author)
Controlling microbubble-mediated drug delivery requires the underlying biological and physical mechanisms to be unraveled. To image both microbubble oscillation upon ultrasound insonification and the resulting cellular response, we developed an optical imaging system that can achieve the necessary nanosecond temporal and nanometer spatial...
journal article 2019
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Karuna, A. (author), Masia, Francesco (author), Wiltshire, Marie (author), Errington, Rachel (author), Borri, Paola (author), Langbein, Wolfgang (author)
Quantitative determination of the chemical composition of unstained samples, non-invasively, with high three- dimensional spatio-temporal resolution, will accelerate progress in cell biology. The current state of the art in bioimaging is dominated by either chemically non-specific or invasive methods. In this work, we demonstrate label-free,...
conference paper 2019
Searched for: subject:"microscopy"
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