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Rafigh Doost, J. (author), Kolenov, D. (author), Pereira, S.F. (author)It has been a widely growing interest in using silicon carbide (SiC) in high-power electronic devices. Yet, SiC wafers may contain killer defects that could reduce fabrication yield and make the device fall into unexpected failures. To prevent these failures from happening, it is very important to develop inspection tools that can detect,...journal article 2023
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Maddalena, L. (author)Optogenetics is a powerful addition to the spectrum of techniques available in neuroscience to investigate neurophysiology and unravel how neural circuit structure is related to circuit function. This technique relies on introducing lightsensitive proteins or molecules as actuators to transduce an optical signal into a physiological perturbation...doctoral thesis 2022
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Meng, X. (author), Huismans, Lex (author), Huijben, T.A.P.M. (author), Szabó, G.V. (author), van Tol, R.F.C. (author), De Heer, Izak (author), Ganapathy, S. (author), Brinks, D. (author)Voltage imaging and optogenetics offer new routes to optically detect and influence neural dynamics. Optimized hardware is necessary to make the most of these new techniques. Here we present the Octoscope, a versatile, multimodal device for all-optical electrophysiology. We illustrate its concept and design and demonstrate its capability to...journal article 2022
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Büke, F. (author), Grilli, Jacopo (author), Cosentino Lagomarsino, Marco (author), Bokinsky, G.E. (author), Tans, S.J. (author)Growth and division are central to cell size. Bacteria achieve size homeostasis by dividing when growth has added a constant size since birth, termed the adder principle, by unknown mechanisms.<sup>1</sup><sup>,</sup><sup>2</sup> Growth is well known to be regulated by guanosine tetraphosphate (ppGpp), which controls diverse processes from...journal article 2022
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Faraj, Noura (author), Duinkerken, B. H.Peter (author), Carroll, E.C.M. (author), Giepmans, Ben N.G. (author)Microscopic analysis of molecules and physiology in living cells and systems is a powerful tool in life sciences. While in vivo subcellular microscopic analysis of healthy and diseased human organs remains impossible, zebrafish larvae allow studying pathophysiology of many organs using in vivo microscopy. Here, we review the potential of the...review 2022
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Bijster, R.J.F. (author)In this thesis a proof-of-principle demonstration is developed that uses the heat flux between a probe and a sample as a proxy for their separation. The proposed architecture uses a probe that consists of a bilayer cantilever with an attached sphere at its free end. The deflection of the cantilever that is caused by the heat input is measured...doctoral thesis 2021
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Quan, D. (author), Moloney, Peter (author), Carolan, Declan (author), Abourayana, Hisham (author), Ralph, Calvin (author), Ivankovic, Alojz (author), Dowling, Denis (author), Murphy, Neal (author)This work studied the effects of adding short basalt fibers (BFs) and multi-walled carbon nanotubes (MWCNTs), both separately and in combination, on the mechanical properties, fracture toughness, and electrical conductivity of an epoxy polymer. The surfaces of the short BFs were either treated using a silane coupling agent or further...journal article 2021
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Santos, Luis F.P. (author), Ribeiro, Bruno (author), Hein, Luis R.O. (author), Alderliesten, R.C. (author), Zarouchas, D. (author), Botelho, Edson C. (author), Costa, Michelle L. (author)This work concerns the fatigue behavior at three different temperature conditions (−40, 20, and 80°C) and the addition of multiwalled carbon nanotube (MWCNT) into a carbon-fiber reinforced poly(ether-imide) composite. The incorporation of MWCNT into the composite increased the tensile strength and Young's modulus by up 5 and 2%, respectively....journal article 2020
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Wilding, D. (author)The goal of this thesis, called Physical and Computational Approaches to Aberration Correction In Fluorescence Microscopy, concerns itself with the development of new techniques to control adaptive fluorescence microscopes, so that they can adapt and image with increased resolution, contrast and speed inside complex three-dimensional biological...doctoral thesis 2018
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Antolović, I.M. (author)The aim of this research is to explore the potential advantages of SPAD imagers used in microscopy. An ideal microscopy detector requires high sensitivity (high quantum efficiency QE or photon detection probability PDP), photon counting operation, low noise (dark current or dark count rate), timing resolution in the order of 100 ps, frame rate...doctoral thesis 2018
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Wilding, D. (author), Pozzi, P. (author), Soloviev, O.A. (author), Vdovin, Gleb (author), Fiolka, Reto (author), Verhaegen, M.H.G. (author)The light-sheet fluorescence microscopy is an excellent tool for the investigation of large three dimensional microscopy samples at the cellular level, however, the ability to resolve features is strongly affected by the presence of scattering and aberrations. These effects are two fold in light-sheet microscopy, as the illumination path...conference paper 2018
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de Rooij, Mario R. (author), França de Mendonça Filho, F. (author)In this article a trip is taken to characterize concrete through its hardened cement paste based on its microstructure. Optical microscopy is coupled to advanced image analysis, as well as statistical data analysis to characterize heterogeneous concrete material. The article takes a closer look at the determination of the w/c ratio through the...conference paper 2017
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Wilding, D. (author), Pozzi, P. (author), Soloviev, O.A. (author), Vdovin, Gleb (author), Verhaegen, M.H.G. (author)Aberrations, scattering and absorption degrade the performance light-sheet fluorescence microscopes (LSFM). An adaptive optics system to correct for these artefacts and to optimize the light-sheet illumination is presented. This system allows a higher axial resolution to be recovered over the field-of-view of the detection objective. It is...conference paper 2016
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Van der Velde, O. (author), Copuroglu, O. (author), Veer, F.A. (author)This paper shows the benefit of using transmitted light microscopy together with a Z-scanning software in fractographical analyses of glass. The strength of glass is largely dependent on processes that happen at the microscale. In this research, 52 plates were fractured in a biaxial tensile test. These were divided into five categories according...conference paper 2015
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Moolman, M.C. (author)Investigating DNA replication in live E. coli cells using fluorescence microscopy and microfluidics.doctoral thesis 2015
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Narváez, A.C. (author)Cathodoluminescence (CL), the excitation of light by an electron beam, has gained attention as an analysis tool for investigating the optical response of a structure, at a resolution that approaches that in electron microscopy, in the nanometer range. However, the application possibilities are limited because the use of transparent substrates,...doctoral thesis 2014
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Damsgaard, C.D. (author), Zandbergen, H.W. (author), Hansen, T.W. (author), Chorkendorff, I. (author), Wagner, J.B. (author)Specimen transfer under controlled environment conditions, such as temperature, pressure, and gas composition, is necessary to conduct successive complementary in situ characterization of materials sensitive to ambient conditions. The in situ transfer concept is introduced by linking an environmental transmission electron microscope to an in...journal article 2014
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Heyer, A. (author)Microbiologically influenced corrosion (MIC) is known to be a dangerous process in ship tanks due to its rapid and yet unpredictable occurrence, leading to extremely fast local corrosion, possibly jeopardizing the structural integrity, in a relatively short time. This project focuses on a fundamental understanding of MIC processes in ship...doctoral thesis 2013
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Celler, K. (author), Picioreanu, C. (author), Van Loosdrecht, M.C.M. (author), Van Wezel, G.P. (author)Successful application of a computational model for rational design of industrial Streptomyces exploitation requires a better understanding of the relationship between morphology—dictated by microbial growth, branching, fragmentation and adhesion—and product formation. Here we review the state-of-the-art in modeling of growth and product...journal article 2012
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Hulsken, B. (author), Vossen, D. (author), Stallinga, S. (author)Array illuminators generating spots with high NA at high efficiency are presented. They are designed via application of high-NA scalar optics methods, and implemented as periodic binary phase structures. These array illuminators are used in a multi-spot scanning microscope for scanning large sample areas with a relatively high resolution.journal article 2012
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