Searched for: subject%3A%22microscopy%22
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Tišma, M. (author), Kaljević, Jovana (author), Gruber, Stephan (author), Le, Tung B.K. (author), Dekker, C. (author)
Bacterial cells require DNA segregation machinery to properly distribute a genome to both daughter cells upon division. The most common system involved in chromosome and plasmid segregation in bacteria is the ParABS system. A core protein of this system - partition protein B (ParB) - regulates chromosome organization and chromosome...
review 2024
document
Mahmoudabadi, Parvin (author), Tavakoli-Kakhki, Mahsan (author), Hassan HosseinNia, S. (author)
Accurate representation of the atomic force microscopy (AFM) system is not only necessary to achieve control objectives, but it is also beneficial for detecting the nanomechanical properties of the samples. To this end, this paper addresses the issue of controller design for the AFM system based on an accurate nonaffine nonlinear distributed...
journal article 2022
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Ando, Toshio (author), Bhamidimarri, Satya Prathyusha (author), Brending, Niklas (author), Colin-York, H. (author), Collinson, Lucy (author), De Jonge, Niels (author), De Pablo, P. J. (author), Debroye, Elke (author), Eggeling, Christian (author), Franck, Christian (author), Hoogenboom, J.P. (author)
Developments in microscopy have been instrumental to progress in the life sciences, and many new techniques have been introduced and led to new discoveries throughout the last century. A wide and diverse range of methodologies is now available, including electron microscopy, atomic force microscopy, magnetic resonance imaging, small-angle x...
review 2018
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Eeftens, J.M. (author)
Every cell deals with the challenge of organising its DNA. First, the DNA needs to be compacted in size by several orders of magnitude. For example, in each human cell, 2 meters of DNA need to fit inside a micron-sized cell nucleus. Second, the DNA needs to stay accessible for cellular processes such as transcription and replication. To achieve...
doctoral thesis 2017
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Nanda, G. (author), Van Veldhoven, E. (author), Maas, D. (author), Sadeghian, H. (author), Alkemade, P.F.A. (author)
The authors report the direct-write growth of hammerhead atomic force microscope(AFM) probes by He+beam induced deposition of platinum-carbon. In order to grow a thin nanoneedle on top of a conventional AFM probe, the authors move a focused He+beam during exposure to a PtC precursor gas. In the final growth stage, a perpendicular movement of the...
journal article 2015
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Herfst, R. (author), Dekker, B. (author), Witvoet, G. (author), Crowcombe, W.E. (author), de Lange, D. (author), Sadeghian Marnani, H. (author)
One of the major limitations in the speed of the atomic force microscope (AFM) is the bandwidth of the mechanical scanning stage, especially in the vertical (z) direction. According to the design principles of “light and stiff” and “static determinacy,” the bandwidth of the mechanical scanner is limited by the first eigenfrequency of the AFM...
journal article 2015
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Gaitas, A. (author)
This dissertation aims to advance the current state of cantilevers with integrated metal thermal and deflection sensing elements. Metallic sensing elements enable the use of alternative substrate materials (such as polymers), that tend to exhibit higher compliance properties and are more robust (less brittle) compared to Si or Si3N4 cantilevers....
doctoral thesis 2013
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Brancart, J. (author), Scheltjes, G. (author), Diaz, M.M. (author), Van Mele, B. (author), Van Assche, G. (author)
Research in the field of smart materials that exhibit self-repair mechanisms has greatly expanded over the last few years. This is especially true for polymers and polymer composite materials. One class of self-healing polymer materials is the reversible polymer network systems that use dynamic covalent bonds as a means to repair sustained...
conference paper 2013
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Goossens, A.M. (author), Calado, V.E. (author), Barreiro, A. (author), Watanabe, K. (author), Taniguchi, T. (author), Vandersypen, L.M.K. (author)
Contamination of graphene due to residues from nanofabrication often introduces background doping and reduces electron mobility. For samples of high electronic quality, post-lithography cleaning treatments are therefore needed. We report that mechanical cleaning based on contact mode atomic force microscopy removes residues and significantly...
journal article 2012
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Gaitas, A. (author), Gianchandani, S. (author), Zhu, W. (author)
Thermomechanical analysis (TMA) is widely used to characterize materials and determine transition temperatures and thermal expansion coefficients. Atomic-force microscopy (AFM) microcantilevers have been used for TMA. We have developed a micromachined probe that includes two embedded sensors: one for measuring the mechanical movement of the...
journal article 2011
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Wnuk, J.D. (author), Gorham, J.M. (author), Rosenberg, S.G. (author), Madey, T.E. (author), Hagen, C.W. (author), Fairbrother, D.H. (author)
Focused electron beam induced processing (FEBIP) of volatile organometallic precursors has become an effective and versatile method of fabricating metal-containing nanostructures. However, the electron stimulated decomposition process responsible for the growth of these nanostructures traps much of the organic content from the precursor’s ligand...
journal article 2010
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Wnuk, J.D. (author), Gorham, J.M. (author), Rosenberg, S.G. (author), Van Dorp, W.F. (author), Madey, T.E. (author), Hagen, C.W. (author), Fairbrother, D.H. (author)
Electron beam induced deposition of organometallic precursors has emerged as an effective and versatile method for creating two-dimensional and three-dimensional metal-containing nanostructures. However, to improve the properties and optimize the chemical composition of nanostructures deposited in this way, the electron stimulated decomposition...
journal article 2010
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Sidorkin, V. (author), Van der Drift, E.W.J.M. (author), Salemink, H. (author)
Performance of hydrogen silsesquioxane (HSQ) resist material with respect to the temperature during electron beam exposure was investigated. Electron beam exposure at elevated temperatures up to 90?°C shows sensitivity rise and slight contrast (?) degradation compared to lower temperature cases. Ultrahigh resolution structures formed at elevated...
journal article 2008
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Weis, C.D. (author), Schuh, A. (author), Batra, A. (author), Persaud, A. (author), Rangelow, I.W. (author), Bokor, J. (author), Lo, C.C. (author), Cabrini, S. (author), Sideras-Haddad, E. (author), Fuchs, G.D. (author), Hanson, R. (author), Awschalom, D.D. (author), Schenkel, T. (author)
The ability to inject dopant atoms with high spatial resolution, flexibility in dopant species, and high single ion detection fidelity opens opportunities for the study of dopant fluctuation effects and the development of devices in which function is based on the manipulation of quantum states in single atoms, such as proposed quantum computers....
journal article 2008
document
Ishii, M. (author), Hamilton, B. (author), Poolton, N. (author)
We have observed the distribution of electron trapping centers on distorted carbon nanotubes (CNTs) by a unique x-ray analysis technique that has both elemental and spatial selectivities. This technique involves the use of scanning probe microscopy (SPM) under synchrotron radiation excitation of the inner shell of carbon. The probe detects the...
journal article 2008
document
Poot, M. (author), Van der Zant, H.S.J. (author)
We have measured the mechanical properties of few-layer graphene and graphite flakes that are suspended over circular holes. The spatial profile of the flake’s spring constant is measured with an atomic force microscope. The bending rigidity of and the tension in the membranes are extracted by fitting a continuum model to the data. For flakes...
journal article 2008
document
Hasan, M.N. (author)
In Pyrococcus furiosus (Pfu) ferredoxin (Fd) replaces NAD+ for carrying reducing equivalent to the oxidative phosphorylation machinery, and it also takes part in the regeneration of NADPH, which is necessary for biosynthetic pathways. Therefore, it plays a central role in various metabolic pathways of the organism. PfuFd is one of the most...
doctoral thesis 2008
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Tatur, J. (author)
This research focuses on the iron storage protein ferritin. Ferritin is a protein involved in iron homeostasis by storing Fe(II) excess in the form of an Fe(III) mineral core in the presence of oxygen and by releasing iron during iron deficiency. Ferritins are vital for human health. Their malfunction may lead among other diseases to anemia,...
doctoral thesis 2007
document
van der Heijden, A.H. (author)
What happens when your DNA breaks? This thesis describes experimental work on the single-molecule level focusing on the interaction between DNA and DNA-repair proteins, in particular bacterial RecA and human Rad51, involved in homologous recombination. Homologous recombination and its central event of DNA strand exchange are essential processes...
doctoral thesis 2007
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Durkut, M. (author), Mas-Torrent, M. (author), Hadley, P. (author), Jonkheijm, P. (author), Schenning, A.P.H.J. (author), Meijer, E.W. (author), George, S. (author), Ajayaghosh, A. (author)
The electrical properties of supermolecular assemblies of oligo(p-phenylene vinylene) were studied. These materials self-assemble into well-defined cylindrical structures in solution with lengths in the range of 100?nm–10??m and diameters between 5 and 200?nm. Atomic force microscopy showed that by adjusting the concentration, either individual...
journal article 2006
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