Searched for: subject%3A%22monolithic%255C%2Bscintillator%255C%2Bdetector%22
(1 - 9 of 9)
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Borghi, G. (author)
Nuclear medical imaging (NMI) is the branch of nuclear medicine aimed at imaging the in-vivo distribution of specific compounds labeled with radioactive elements (radiotracers) inside animals (preclinical applications) or patients (clinical applications). These compounds are developed to follow metabolic pathways or for binding to receptor...
doctoral thesis 2021
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Borghi, G. (author), Tabacchini, V. (author), Bakker, P.J. (author), Schaart, D.R. (author)
Recently, a monolithic scintillator detector for time-of-flight (TOF)/depth-of-interaction (DOI) positron emission tomography (PET) was developed. It has a detector spatial resolution of ∼1.7 mm full-width-at-half-maximum (FWHM), a coincidence resolving time (CRT) of ∼215 ps FWHM, and ∼4.7 mm FWHM DOI resolution. Here, we demonstrate, for the...
journal article 2018
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Tabacchini, V. (author), Surti, Suleman (author), Borghi, G. (author), Karp, Joel S. (author), Schaart, D.R. (author)
We have recently built and characterized the performance of a monolithic scintillator detector based on a 32 mm × 32 mm × 22 mm LYSO:Ce crystal read out by digital silicon photomultiplier (dSiPM) arrays coupled to the crystal front and back surfaces in a dual-sided readout (DSR) configuration. The detector spatial resolution appeared to be...
journal article 2017
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Borghi, G. (author), Tabacchini, V. (author), Schaart, D.R. (author)
Gamma-ray detectors based on thick monolithic scintillator crystals can achieve spatial resolutions <2 mm full-width-at-half-maximum (FWHM) and coincidence resolving times (CRTs) better than 200 ps FWHM. Moreover, they provide high sensitivity and depth-of-interaction (DOI) information. While these are excellent characteristics for...
journal article 2016
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Borghi, G. (author), Peet, B.J.A. (author), Tabacchini, V. (author), Schaart, D.R. (author)
New applications for positron emission tomography (PET) and combined PET/magnetic resonance imaging (MRI) are currently emerging, for example in the fields of neurological, breast, and pediatric imaging. Such applications require improved image quality, reduced dose, shorter scanning times, and more precise quantification. This can be...
journal article 2016
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Tabacchini, V. (author), Borghi, G. (author), Schaart, D.R. (author)
Gamma-ray detectors based on bright monolithic scintillation crystals coupled to pixelated photodetectors are currently being considered for several applications in the medical imaging field. In a typical monolithic detector, both the light intensity and the time of arrival of the earliest scintillation photons can be recorded by each of the...
journal article 2015
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Van der Laan, D.J. (author)
Monolithic scintillator detectors are very promising for high-resolution high-sensitivity PET. These detectors consist of several cubic centimetres of scintillating material coupled on one or more sides to position-sensitive avalanche photo-diode (APD) arrays. The coordinates of the entry point of an incoming gamma photon are estimated from the...
doctoral thesis 2009
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Maas, M.C. (author)
Positron emission tomography (PET) is a technique for imaging the 3-dimensional distribution of radio-labelled molecules in vivo. This technique plays an increasingly important role in preclinical research involving mice and rats. The small dimensions of these animals impose stringent requirements on both the image resolution and the sensitivity...
doctoral thesis 2008
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Maas, M. (author), Schaart, D.R. (author), Van der Laan, D.J. (author), Van Dam, T. (author), Huizenga, J. (author), Brouwer, J.C. (author), Bruyndonckx, P. (author), Lemaitre, C. (author), Van Eijk, C.W.E. (author)
journal article 2008
Searched for: subject%3A%22monolithic%255C%2Bscintillator%255C%2Bdetector%22
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