Modelling Micromotion of Implants in the Rat Femur: A rat femoral knee prosthesis to simulate aseptic loosening

Background: Aseptic loosening [AL] of cementless implants is causing approximately 60% of total knee and total hip arthroplasty revisions. AL is caused among other factors by micromotion. The result is that the bone around the prosthesis is replaced by a fibrous membrane. This fibrous membrane allows for more micromotion and we thus enter a...