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The contribution of deeper layers in slow sand filters to pathogens removal

Trikannad, S.A. (author), van Halem, D. (author), Foppen, J.W.A. (author), van der Hoek, J.P. (author)

Slow Sand Filtration is popular in drinking water treatment for the removal of a wide range of contaminants (e.g., particles, organic matter, and microorganisms). The Schmutzdecke in slow sand filters (SSFs) is known to be essential for pathogen removal, however, this layer is also responsible for increased head loss. Since the role of deeper...

journal article 2023

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Numerical simulation framework for radio wave soil treatment for pathogen suppression

Sturm, G.S.J. (author), van der Wurff, A. (author), Linnenbank, S. (author), Bonnet, J. (author), Koppert, A. (author)

Thermal pathogen suppression in glasshouse horticulture by treatment with steam generated through combustion of fossil fuel will become progressively less desirable. Radio wave treatment could be an alternative. It has several advantages, the most notable is that it generates heat where it is needed in soil, so that it avoids heat losses and...

journal article 2023

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Rapid Multivariate Analysis Approach to Explore Differential Spatial Protein Profiles in Tissue

Sharman, Kavya (author), Patterson, Nathan Heath (author), Weiss, Andy (author), Neumann, Elizabeth K. (author), Guiberson, Emma R. (author), Ryan, Daniel J. (author), Gutierrez, Danielle B. (author), Spraggins, Jeffrey M. (author), Van de Plas, Raf (author), Skaar, Eric P. (author), Caprioli, Richard M. (author)

Spatially targeted proteomics analyzes the proteome of specific cell types and functional regions within tissue. While spatial context is often essential to understanding biological processes, interpreting sub-region-specific protein profiles can pose a challenge due to the high-dimensional nature of the data. Here, we develop a multivariate...

journal article 2023

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Removal of bacterial plant pathogens in columns filled with quartz and natural sediments under anoxic and oxygenated conditions

Eisfeld, R.C.M. (author), Schijven, Jack F. (author), van der Wolf, Jan M. (author), Medema, G.J. (author), Kruisdijk, E. (author), van Breukelen, B.M. (author)

Irrigation with surface water carrying plant pathogens poses a risk for agriculture. Managed aquifer recharge enhances fresh water availability while simultaneously it may reduce the risk of plant diseases by removal of pathogens during aquifer passage. We compared the transport of three plant pathogenic bacteria with Escherichia coli WR1 as...

journal article 2022

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Seawater desalination based drinking water: Microbial characterization during distribution with and without residual chlorine

Farhat, Nadia (author), Kim, Lanhee (author), Mineta, Katsuhiko (author), Alarawi, Mohammed (author), Gojobori, Takashi (author), Saikaly, Pascal (author), Vrouwenvelder, J.S. (author)

Monitoring the changes that occur to water during distribution is vital to ensure water safety. In this study, the biological stability of reverse osmosis (RO) produced drinking water, characterized by low cell concentration and low assimilable organic carbon, in combination with chlorine disinfection was investigated. Water quality at...

journal article 2022

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Visualizing Staphylococcus aureus pathogenic membrane modification within the host infection environment by multimodal imaging mass spectrometry

Perry, William J. (author), Grunenwald, Caroline M. (author), Van de Plas, Raf (author), Witten, James C. (author), Martin, Daniel R. (author), Apte, Suneel S. (author), Cassat, James E. (author), Pettersson, Gösta B. (author), Caprioli, Richard M. (author), Skaar, Eric P. (author), Spraggins, Jeffrey M. (author)

Bacterial pathogens have evolved virulence factors to colonize, replicate, and disseminate within the vertebrate host. Although there is an expanding body of literature describing how bacterial pathogens regulate their virulence repertoire in response to environmental signals, it is challenging to directly visualize virulence response within...

journal article 2022

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Impact of sink design on bacterial transmission from hospital sink drains to the surrounding sink environment tested using a fluorescent marker

Pirzadian, J. (author), Souhoka, T. (author), Herweijer, M. (author), van Heel, M.E. (author), van Wamel, W. J.B. (author), Goossens, R.H.M. (author), Severin, J. A. (author), Vos, M. C. (author)

In hospitals, sinks act as reservoirs for bacterial pathogens. To assess the extent of splashing, fluorescein dye was added to four hospital sinks previously involved in pathogen dispersal to the environment and/or transmission to patients, and one sink that was not. Applying dye to the p-trap or tailpiece did not result in any fluorescent...

journal article 2022

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Efficient cooling tower operation at alkaline pH for the control of Legionella pneumophila and other pathogenic genera

Pinel, I.S.M. (author), Hankinson, P. M. (author), Moed, D. H. (author), Wyseure, L. J. (author), Vrouwenvelder, J.S. (author), van Loosdrecht, Mark C.M. (author)

Efficient control of pathogenic bacteria, specifically Legionella pneumophila, is one of the main concerns when operating industrial cooling towers. Common practices to limit proliferation involves use of disinfectants, leading to formation of disinfection by-product and increase in water corrosiveness. A disinfectant-free Legionella control...

journal article 2021

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Model development for evidence-based prioritisation of policy action on emerging chemical and microbial drinking water risks

Hartmann, J. (author), Chacon Hurtado, J.C. (author), Verbruggen, Eric (author), Schijven, Jack (author), Rorije, Emiel (author), Wuijts, Susanne (author), de Roda Husman, Ana Maria (author), van der Hoek, J.P. (author), Scholten, L. (author)

While the burden of disease from well-studied drinking water contaminants is declining, risks from emerging chemical and microbial contaminants arise because of social, technological, demographic and climatological developments. At present, emerging chemical and microbial drinking water contaminants are not assessed in a systematic way, but...

journal article 2021

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Passive Sampling of SARS-CoV-2 for Wastewater Surveillance

Schang, Christelle (author), Crosbie, Nicolas D. (author), Nolan, Monica (author), Poon, Rachael (author), WANG, M. (author), Jex, Aaron (author), John, Nijoy (author), Baker, Louise (author), Langeveld, J.G. (author)

The shedding of pathogens by infected humans enables the use of sewage monitoring to conduct wastewater-based epidemiology (WBE). Although most WBE studies use data from large sewage treatment plants, timely data from smaller catchments are needed for targeted public health action. Traditional sampling methods, like autosamplers or grab...

journal article 2021

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Respiratory infection risk-based ventilation design method

Kurnitski, Jarek (author), Kiil, Martin (author), Wargocki, Pawel (author), Boerstra, A.C. (author), Seppänen, Olli (author), Olesen, Bjarne (author), Morawska, Lidia (author)

A new design method is proposed to calculate outdoor air ventilation rates to control respiratory infection risk in indoor spaces. We propose to use this method in future ventilation standards to complement existing ventilation criteria based on the perceived air quality and pollutant removal. The proposed method makes it possible to...

journal article 2021

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Low voltage iron electrocoagulation as a tertiary treatment of municipal wastewater: removal of enteric pathogen indicators and antibiotic-resistant bacteria

Bicudo, Bruno (author), van Halem, D. (author), Trikannad, S.A. (author), Ferrero, Giuliana (author), Medema, G.J. (author)

In this paper we analyse the feasibility of low voltage iron electrocoagulation as a means of municipal secondary effluent treatment with a focus on removal of microbial indicators, Antibiotic Resistant Bacteria (ARB) and nutrients. A laboratory scale batch unit equipped with iron electrodes was used on synthetic and real secondary effluent...

journal article 2021

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Unravelling the removal mechanisms of bacterial and viral surrogates in aerobic granular sludge systems

Barrios Hernandez, M.L. (author), Bettinelli, Carolina (author), Mora-Cabrera, Karen (author), Vanegas-Camero, Maria Clara (author), Garcia, H. (author), van de Vossenberg, Jack (author), Prats, Daniel (author), Brdjanovic, Damir (author), van Loosdrecht, Mark C.M. (author)

The aerobic granular sludge (AGS) process is an effective wastewater treatment technology for organic matter and nutrient removal that has been introduced in the market rapidly. Until now, limited information is available on AGS regarding the removal of bacterial and viral pathogenic organisms present in sewage. This study focussed on...

journal article 2021

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Use of therapeutic pathogen recognition receptor ligands for osteo-immunomodulation

Khokhani, Paree (author), Rahmani, Nada R. (author), Kok, Anne (author), Öner, F. Cumhur (author), Alblas, Jacqueline (author), Weinans, Harrie (author), Kruyt, Moyo C. (author), Croes, Michiel (author)

Therapeutic pathogen recognition receptor (PRR) ligands are reaching clinical practice following their ability to skew the immune response in a specific direction. We investigated the effects of various therapeutic PRR ligands on bone cell differentiation and inflammation. Following stimu-lation, alkaline phosphatase (ALP) activity (Day 10),...

journal article 2021

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The effective design of sampling campaigns for emerging chemical and microbial contaminants in drinking water and its resources based on literature mining

Hartmann, J. (author), van Driezum, Inge (author), Ohana, Dana (author), Lynch, Gretta (author), Berendsen, Bjorn (author), Wuijts, Susanne (author), van der Hoek, J.P. (author), de Roda Husman, Ana Maria (author)

As well as known contaminants, surface waters also contain an unknown variety of chemical and microbial contaminants which can pose a risk to humans if surface water is used for the production of drinking water. To protect human health proactively, and in a cost-efficient way, water authorities and drinking water companies need early warning...

journal article 2020

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Removal of bacterial and viral indicator organisms in full-scale aerobic granular sludge and conventional activated sludge systems

Barrios Hernandez, M.L. (author), Pronk, M. (author), Garcia, H. (author), Boersma, Arne (author), Brdjanovic, Damir (author), van Loosdrecht, Mark C.M. (author), Hooijmans, Christine M. (author)

The aim of this study was to evaluate the effectiveness of the novel aerobic granular sludge (AGS) wastewater treatment technology in removing faecal indicator organisms (FIOs) compared to the conventional activated sludge (CAS) treatment system. The work was carried out at two full-scale wastewater treatment plants (WWTP) in the Netherlands,...

journal article 2020

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Effects of cold recovery technology on the microbial drinking water quality in unchlorinated distribution systems

Ahmad, J.I. (author), Liu, G. (author), van der Wielen, Paul (author), Medema, G.J. (author), van der Hoek, J.P. (author)

Drinking water distribution systems (DWDSs) are used to supply hygienically safe and biologically stable water for human consumption. The potential of thermal energy recovery from drinking water has been explored recently to provide cooling for buildings. Yet, the effects of increased water temperature induced by this “cold recovery” on the...

journal article 2020

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Use of literature mining for early identification of emerging contaminants in freshwater resources

Hartmann, J. (author), Wuijts, Susanne (author), van der Hoek, J.P. (author), de Roda Husman, Ana Maria (author)

Chemical and microbial contaminants in the aquatic environment pose a potential threat to humans and to ecosystems. Humans may be exposed to contaminants in water resources when used for drinking water production, agriculture, aquaculture or recreation. Climatological, social and demographic changes, as well as the increasing sensitivity of...

journal article 2019

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Volatile fatty acids build-up and its effect on E. coli inactivation during excreta stabilisation in single-stage and two-stage systems

Riungu, J. (author), Ronteltap, Mariska (author), van Lier, J.B. (author)

Digestion and co-digestion of faecal matter collected from urine diverting dehydrating toilet faeces (UDDT-F) and mixed organic market waste (OMW) was studied in single stage pilot scale mesophilic plug-flow anaerobic reactors at UDDT-F:OMW ratios 4:1 and 1:0. Escherichia coli inactivation and volatile fatty acids (VFA) build-up was monitored...

journal article 2018

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A pilot-scale microwave technology for sludge sanitization and drying

Mawioo, P.M. (author), Garcia, Hector A. (author), Hooijmans, Christine M. (author), Velkushanova, Konstantina (author), Simonič, Marjana (author), Mijatović, Ivan (author), Brdjanovic, Damir (author)

Large volumes of sludge are produced from onsite sanitation systems in densely populated areas (e.g. slums and emergency settlements) and wastewater treatment facilities that contain high amounts of pathogens. There is a need for technological options which can effectively treat the rapidly accumulating sludge under these conditions. This...

journal article 2017