Searched for: subject%3A%22positron%255C%2Bemission%255C%2Btomography%255C%2B%255C%2528PET%255C%2529%22
(1 - 11 of 11)
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Lacerda, Sara (author), Zhang, W. (author), T. M. De Rosales, Rafael (author), Da Silva, Isidro (author), Sobilo, Julien (author), Lerondel, Stéphanie (author), Tóth, Éva (author), Djanashvili, K. (author)
Porous materials, such as zeolites, have great potential for biomedical applications, thanks to their ability to accommodate positively charged metal-ions and their facile surface functionalization. Although the latter aspect is important to endow the nanoparticles with chemical/colloidal stability and desired biological properties, the...
journal article 2022
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Goorden, M.C. (author), Kamphuis, Chris (author), Ramakers, R.M. (author), Beekman, F.J. (author)
Today, versatile emission computed tomography (VECTor) technology using dedicated high-energy collimation enables simultaneous positron emission tomography (PET) and single photon emission computed tomography (SPECT) down to 0.6 mm and 0.4 mm resolution in mice, respectively. We recently showed that for optimal resolution and quantitative...
journal article 2020
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Brown, J.M.C. (author), Brunner, S. (author), Schaart, D.R. (author)
Organ-specific, targeted field-of-view (FoV) positron emission tomography (PET)/magnetic resonance imaging (MRI) inserts are viable solutions for a number of imaging tasks where whole-body PET/MRI systems lack the necessary sensitivity and resolution. To meet the required PET detector performance of these systems, high count-rates and...
journal article 2020
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Venialgo Araujo, E. (author), Lusardi, Nicola (author), Garzetti, Fabio (author), Geraci, Angelo (author), Brunner, S. (author), Schaart, D.R. (author), Charbon-Iwasaki-Charbon, E. (author)
Typically, a time-of-flight (TOF) PET block detector is built using application-specific integrated circuits (ASICs), since they integrate a high number of channels at a reasonable power consumption and into a small area. However, ASICs’ flexibility is limited and prototyping times are long because a semiconductor fabrication process is required...
journal article 2018
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Borghi, G. (author), Tabacchini, V. (author), Schaart, D.R. (author)
Gamma-ray detectors based on thick monolithic scintillator crystals can achieve spatial resolutions <2 mm full-width-at-half-maximum (FWHM) and coincidence resolving times (CRTs) better than 200 ps FWHM. Moreover, they provide high sensitivity and depth-of-interaction (DOI) information. While these are excellent characteristics for...
journal article 2016
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Borghi, G. (author), Peet, B.J.A. (author), Tabacchini, V. (author), Schaart, D.R. (author)
New applications for positron emission tomography (PET) and combined PET/magnetic resonance imaging (MRI) are currently emerging, for example in the fields of neurological, breast, and pediatric imaging. Such applications require improved image quality, reduced dose, shorter scanning times, and more precise quantification. This can be...
journal article 2016
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Goorden, M.C. (author), van Roosmalen, J. (author), van der Have, F. (author), Beekman, F.J. (author)
The recently developed versatile emission computed tomography (VECTor) technology enables high-energy SPECT and simultaneous SPECT and PET of small animals at sub-mm resolutions. VECTor uses dedicated clustered pinhole collimators mounted in a scanner with three stationary large-area NaI(Tl) gamma detectors. Here, we develop and validate...
journal article 2016
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Tabacchini, V. (author), Borghi, G. (author), Schaart, D.R. (author)
Gamma-ray detectors based on bright monolithic scintillation crystals coupled to pixelated photodetectors are currently being considered for several applications in the medical imaging field. In a typical monolithic detector, both the light intensity and the time of arrival of the earliest scintillation photons can be recorded by each of the...
journal article 2015
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Beekman, F.J. (author), Vastenhouw, B. (author), Van der Wilt, G. (author), Vervloet, M. (author), Visscher, R. (author), Booij, J. (author), Gerrits, M. (author), Ji, C. (author), Ramakers, R. (author), Van der Have, F. (author)
With the steadily improving resolution of novel small-animal single photon emission computed tomography (SPECT) and positron emission tomography devices, highly detailed phantoms are required for testing and optimizing these systems. We present a three-dimensional (3-D) digital and physical phantom pair to represent, e.g., cerebral blood flow,...
journal article 2009
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Maas, M.C. (author)
Positron emission tomography (PET) is a technique for imaging the 3-dimensional distribution of radio-labelled molecules in vivo. This technique plays an increasingly important role in preclinical research involving mice and rats. The small dimensions of these animals impose stringent requirements on both the image resolution and the sensitivity...
doctoral thesis 2008
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Maas, M. (author), Schaart, D.R. (author), Van der Laan, D.J. (author), Van Dam, T. (author), Huizenga, J. (author), Brouwer, J.C. (author), Bruyndonckx, P. (author), Lemaitre, C. (author), Van Eijk, C.W.E. (author)
journal article 2008
Searched for: subject%3A%22positron%255C%2Bemission%255C%2Btomography%255C%2B%255C%2528PET%255C%2529%22
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