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Greijdanus, A. (author)Asthma and COPD are the largest chronic respiratory diseases. With an estimated 300 million affected individuals, asthma is a worldwide problem. Currently, it is estimated that 210 million people have COPD which is in 95% of all cases are smoking related. Annual worldwide deaths from asthma have been estimated at 250.000. Whereas COPD is...master thesis 2011