Noninvasive Advanced Cardiovascular Magnetic Resonance-Derived Fontan Hemodynamics Are Associated With Reduced Kidney Function But Not Albuminuria

BACKGROUND: Kidney disease is the most important predictor of death in patients with a Fontan circulation, yet its clinical and hemodynamic correlates have not been well established. METHODS AND RESULTS: A total of 53 ambulatory patients with a Fontan circulation (median age, 16.2 years, 52.8% male patients) underwent advanced cardiovascular...

Diastolic strain rate by cardiac MRI for predicting mortality in kidney transplant recipients

Introduction: High cardiovascular mortality primarily limits survival following kidney transplantation (KTx). The increased risk is intrinsically connected to cardiac structural and functional abnormalities. LV volumetric imaging measurements are used to quantify this, such as left ventricular ejection fraction (LVEF) and left ventricular end...

MRI-Compatible Pneumatic Actuation Unit for a Self-Propelling Needle

Focal laser ablation is a new, promising method to treat tumors. The current focal laser ablation approach is to insert an optical fiber into the patient using rigid needles. A side effect of this approach is that during the needle insertion, tissue damage occurs. The larger the diameter of the needle, the more tissue damage. If the diameter of...

Cardiac phase-resolved late gadolinium enhancement imaging

Late gadolinium enhancement (LGE) with cardiac magnetic resonance (CMR) imaging is the clinical reference for assessment of myocardial scar and focal fibrosis. However, current LGE techniques are confined to imaging of a single cardiac phase, which hampers assessment of scar motility and does not allow cross-comparison between multiple phases....

MRI-Ready Actuation System for a Self-Propelling Needle: A Design and Experimental Approach

Standard treatment methods for prostate cancer often result in side-effects because of damage to the surrounding tissue. Magnetic resonance imaging (MRI) guided focal laser ablation to treat prostate cancer reduces the risk of adverse effects by preserving noncancerous tissue. Prostate cancer diagnosis and focal laser ablation treatment both...

Differences Between MR Brain Region Segmentation Methods: Impact on Single-Subject Analysis

For the segmentation of magnetic resonance brain images into anatomical regions, numerous fully automated methods have been proposed and compared to reference segmentations obtained manually. However, systematic differences might exist between the resulting segmentations, depending on the segmentation method and underlying brain atlas. This...

High-permittivity pad design tool for 7T neuroimaging and 3T body imaging

Purpose: High-permittivity materials in the form of flexible “dielectric pads” have proved very useful for addressing RF inhomogeneities in high field MRI systems. Finding the optimal design of such pads is, however, a tedious task, reducing the impact of this technique. We present an easy-to-use software tool which allows researchers and...

Limited added value of magnetic resonance imaging after dynamic transvaginal ultrasound for preoperative staging of endometriosis in daily practice: A prospective cohort study

OBJECTIVES: To assess the added value of magnetic resonance imaging (MRI) after dynamic transvaginal ultrasound (TVUS) in the diagnostic pathway for preoperative staging of pelvic endometriosis. METHODS: A prospective observational study was conducted between April 22, 2014, and May 1, 2015. During that period, 363 patients with a clinical...

3-D Contrast Source Inversion-Electrical Properties Tomography

Contrast source inversion – electrical properties tomography (CSI-EPT) is an iterative reconstruction method to retrieve the electrical properties (EPs) of tissues from MR data. The method is based on integral representations of the electromagnetic (EM) field and has been shown to allow EP reconstructions of small structures as...

The 2018 correlative microscopy techniques roadmap

Developments in microscopy have been instrumental to progress in the life sciences, and many new techniques have been introduced and led to new discoveries throughout the last century. A wide and diverse range of methodologies is now available, including electron microscopy, atomic force microscopy, magnetic resonance imaging, small-angle x...

Blood perfusion of patellar bone measured by dynamic contrast-enhanced MRI in patients with patellofemoral pain: A case–control study

Background: Altered perfusion might play an important role in the pathophysiology of patellofemoral pain (PFP), a common knee complaint with unclear pathophysiology. Purpose: To investigate differences in dynamic contrast-enhanced (DCE)-MRI perfusion parameters between patients with PFP and healthy control subjects. Population/Subjects...

Image reconstruction in low-field MRI: A super-resolution approach

The quality of magnetic resonance images produced by conventional MRI scanners is guaranteed by the strength and homogeneity of the magnetic field. However, the superconducting magnets required to produce such a field make MRI scanners large and expensive and hence inaccessible to a large number of people in developing countries. Our partners...

Gray matter heritability in family-based and population-based studies using voxel-based morphometry

Background: The combination of genetics and imaging has improved their understanding of the brain through studies of aggregate measures obtained from high-resolution structural imaging. Voxel-wise analyses have the potential to provide more detailed information of genetic influences on the brain. Here they report a large-scale study of the...

Corrigendum: EEG beta suppression and low gamma modulation are different elements of human upright walking

A corrigendum on EEG beta suppression and low gamma modulationare different elements of human upright walking by Seeber,M.,Scherer,R.,Wagner,J.,Solis-Escalante,T.,andMüller-Putz,G.R.(2014)Front.Hum. Neurosci.8:485.doi:10.3389/fnhum.2014.00485

Older age relates to worsening of fine motor skills: A population-based study of middle-aged and elderly persons

Introduction: In a population-based study of 1,912 community-dwelling persons of 45 years and older, we investigated the relation between age and fine motor skills using the Archimedes spiral-drawing test. Also, we studied the effect of brain volume on fine motor skills. Methods: Participants were required to trace a template of a spiral on an...

EEG beta suppression and low gamma modulation are different elements of human upright walking

Cortical involvement during upright walking is not well-studied in humans. We analyzed non-invasive electroencephalographic (EEG) recordings from able-bodied volunteers who participated in a robot-assisted gait-training experiment. To enable functional neuroimaging during walking, we applied source modeling to high-density (120 channels) EEG...

A computer-assisted model for detection of MRI signs of Crohn’s disease activity: Future or fiction?

Magnetic resonance imaging is increasingly used for abdominal evaluation and is more and more considered as the optimal imaging technique for detection of mural inflammation in patients with Crohn’s disease. Grading the disease activity is important in daily clinical practice to monitor the medical treatment and is assessed by evaluating...