Searched for: subject:"scaffold"
(1 - 20 of 26)

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Putra, N.E. (author), Leeflang, M.A. (author), Minneboo, M.B. (author), Taheri, P. (author), Fratila-Apachitei, E.L. (author), Mol, J.M.C. (author), Zhou, J. (author), Zadpoor, A.A. (author)
Extrusion-based 3D printing followed by debinding and sintering is a powerful approach that allows for the fabrication of porous scaffolds from materials (or material combinations) that are otherwise very challenging to process using other additive manufacturing techniques. Iron is one of the materials that have been recently shown to be...
journal article 2021
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Dimaraki, Angeliki (author)
The use of allografts for the treatment of critical size cartilage defects holds disadvantages including the limited number of donors and the compromised chondrocyte viability. These limitations have prompted researchers to explore different options, such as cartilage engineering. Bioprinting, a promising tissue engineering technique, could be...
master thesis 2020
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Li, Y. (author)
For the treatment of large bony defects, no perfect solution has been yet found, partially due to the unavailability of ideal bone implants. Additively manufactured (AM) biodegradable porous metals provide unprecedented opportunities to fulfil the requirements for ideal bone implants to be used in such treatments. Firstly, the multi-scale...
doctoral thesis 2020
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Stoof, Jennifer (author)
In an effort to further evaluate the effects of Ecological Interface Design on acquiring expertise, this paper presents the results of an investigation into how Ecological Interface Design could possibly promote discovery learning processes in the Air Traffic Control domain through the application of an instructional design model, and how it...
master thesis 2020
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Ibsen, Oscar (author)
Context. In times where human kind is facing serious challenges due to global warming, scarcity of natural resources and inequality, to continue producing food, especially meat, as it is now done, does not seem sustainable. For people that want to continue enjoying their delicious piece of steak, the manner in which meat is sourced will need to...
master thesis 2020
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Dong, J. (author), Li, Y. (author), Lin, P. (author), Leeflang, M.A. (author), van Asperen, S. (author), Yu, K. (author), Tümer, N. (author), Norder, B. (author), Zadpoor, A.A. (author), Zhou, J. (author)
Biodegradable porous magnesium (Mg) scaffolds are promising for application in the regeneration of critical-sized bone defects. Although additive manufacturing (AM) carries the promise of offering unique opportunities to fabricate porous Mg scaffolds, current attempts to apply the AM approach to fabricating Mg scaffolds have encountered some...
journal article 2020
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Schouten, D.G.M. (author), Massink, Pim (author), Donker, Stella F. (author), Neerincx, M.A. (author)
In this study, we attempt to specify the cognitive support behavior of a previously designed embodied conversational agent coach that provides learning support to low-literates. Three knowledge gaps are identified in the existing work: an incomplete specification of the behaviors that make up ‘support,’ an incomplete specification of how this...
journal article 2020
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Mansoor, Amal (author)
Atherosclerosis is an inflammatory disease characterised by the formation of plaque in the intimal layer of the artery. The plaque is made of a lipid rich necrotic core which is covered by a collagen rich fibrous cap. If this fibrous cap ruptures, it can lead to sudden thrombotic occlusion of the artery. Rupture of the fibrous cap is linked to...
master thesis 2019
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de Vries, Sybren (author)
Although many studies have been performed on porous absorbable iron scaffolds created by the space holder method, no studies have considered the influence of variations in space holders on absorbable scaffolds. The present study aimed to clarify the effects of space holder particle size and volume fraction, on the pore structure, resultant...
master thesis 2019
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Valente, Yara (author)
Society is stuck in daily routines, led by social norms and conventions. Often we are unaware of this, while life can be much richter if we would subvert from these routines every once in a while. These routines prevent us from seeing everything that there is. Our expectations need to be subverted. <br/><br/>Usually it is reserved for artists to...
master thesis 2019
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Li, Y. (author), Lietaert, K. (author), Li, W. (author), Zhang, X.Y. (author), Leeflang, M.A. (author), Zhou, J. (author), Zadpoor, A.A. (author)
The corrosion fatigue behavior of additively manufactured topologically ordered porous iron based on diamond unit cells was studied for the first time to understand its response to cyclic loading in a simulated physiological environment. The material exhibited high fatigue resistance with fatigue strengths being 70% and 65% of yield stress in...
journal article 2019
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De Witte, Tinke-Marie (author)
In recent years, bone tissue engineering has emerged as a promising strategy to overcome the limitations of current ‘gold standard’ treatment options for bone disorders such as bone autografts and allografts. Bone tissue engineering strategies rely on the development of a scaffold that mimics the extracellular matrix, thereby providing an...
master thesis 2018
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Zhang, Xiang Yu (author), Fang, Gang (author), Xing, Lei Lei (author), Liu, Wei (author), Zhou, J. (author)
Functionally graded scaffold (FGS) is designed to mimic the morphology, mechanical and biological properties of natural bone closely. Porosity variation strategy between different regions in FGS plays a crucial role in influencing its mechanical and biological performance. A combination of modeling tool and scripting language can effectively...
journal article 2018
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De Witte, Tinke (author), Fratila-Apachitei, E.L. (author), Zadpoor, A.A. (author), Peppas, Nicholas (author)
In recent years, bone tissue engineering has emerged as a promising solution to the limitations of current gold standard treatment options for bone related-disorders such as bone grafts. Bone tissue engineering provides a scaffold design that mimics the extracellular matrix, providing an architecture that guides the natural bone regeneration...
journal article 2018
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De Vecchi, Riccardo (author)
master thesis 2017
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Arifvianto, B. (author)
Loss of function and impaired life quality as a result of large bone defects remain a serious problem in the society. Basically, the bone tissue has the capability of healing by itself when fractured. However, impaired healing may occur, leading to delayed union or even non-union when a bone segment is excised above a critical size. In recent...
doctoral thesis 2017
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Bogers, Janna (author)
Metal nanoparticles have promising potential for use in medical applications, such as imaging or targeted drug delivery. Current methods of production of nanoparticles are expensive and make use of harsh reagents. Because of these limitations, nanoparticles are not yet widely available, limiting the use in medical applications. To commercialize...
bachelor thesis 2017
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Zhang, X.Y. (author), Fang, G (author), Zhou, J. (author)
Additive manufacturing (AM), nowadays commonly known as 3D printing, is a revolutionary materials processing technology, particularly suitable for the production of low-volume parts with high shape complexities and often with multiple functions. As such, it holds great promise for the fabrication of patient-specific implants. In recent years,...
journal article 2017
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Ye, Xiaotong (author), Leeflang, M.A. (author), Wu, Chengtie (author), Chang, Jiang (author), Zhou, J. (author), Huan, Z. (author)
Porous Ti-6Al-4V scaffolds fabricated by means of selective laser melting (SLM),<br/>having controllable geometrical features and preferable mechanical properties, have been developed as a class of biomaterials that hold promising potential for bone repair. However, the inherent bio-inertness of the Ti-6Al-4V alloy as the matrix of the scaffolds...
journal article 2017
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Hedayati, R. (author), Amin Yavari, S. (author), Zadpoor, A.A. (author)
Additively manufactured porous titanium implants, in addition to preserving the excellent biocompatible properties of titanium, have very small stiffness values comparable to those of natural bones. Although usually loaded in compression, biomedical implants can also be under tensional, shear, and bending loads which leads to crack initiation...
journal article 2017
Searched for: subject:"scaffold"
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