Predicting Infections in Preterm Infants with Thermal Imaging Technology

Neonatal sepsis is a dangerous non-specific disease in babies, especially neonate/newborns. It is one of the leading causes of neonate mortality rate, because of the difficulty to diagnose, leading to late or false treatment. Previous research has found the promising feature of artificial intelligence or machine learning in solving the problem....

Association between the macrocirculation and the mitochondrial oxygenation in critically ill patients with sepsis

IntroductionThe Cellular Oxygen METabolism (COMET) monitor measures mitochondrial oxygentension (mitoPO2) in vivo at the bedside with delayed fluorescence ofmitochondrial protoporphyrin (PpIX). Blocking microcirculatory oxygen supply bypressing the measurement probe on the skin allows the measurement of mitochondrialoxygen...

Predicting sepsis on the Neonatal Intensive Care Unit

To reduce the mortality rate of sepsis, treatment needs to be started as soon as possible. One should however first be sure about the occurrence of sepsis. Currently, the suspicion of sepsis in premature infants is based on non-specific physiological changes. The detection of alterations in the inter-heartbeat interval preceding sepsis can offer...

Thermal Alterations in Premature Neonates

Introduction: Preterm neonates suffer frequent thermal alterations that result in increased morbidity and mortality rates. Thermal support is used to provide stability until thermal maturation is reached. The first manifestation of thermal control is peripheral vasoconstriction, estimated as the difference between central and peripheral...

Design a cellular oxygen consumption measurement system for the diagnosis of Sepsis

The master thesis report shows the process and result of the development of a optical cellular oxygen comsumption system for the diagnosis of Sepsis by using the fluoressing property of Protoporphyrin IX in the skin cells.