Microscopy-Directed Imaging Mass Spectrometry for Rapid High Spatial Resolution Molecular Imaging of Glomeruli

The glomerulus is a multicellular functional tissue unit (FTU) of the nephron that is responsible for blood filtration. Each glomerulus contains multiple substructures and cell types that are crucial for their function. To understand normal aging and disease in kidneys, methods for high spatial resolution molecular imaging within these FTUs...

A 2D Ultrasound Phased-Array Transmitter ASIC for High-Frequency US Stimulation and Powering

Ultrasound (US) neuromodulation and ultrasonic power transfer to implanted devices demand novel ultrasound transmitters capable of steering focused ultrasound waves in 3D with high spatial resolution and US pressure, while having a miniaturized form factor. Meeting these requirements needs a 2D array of ultrasound transducers directly...

Spatial Resolution Matching of Microwave Radiometer Measurements Using Iterative Deconvolution with Close Loop Priors (ICLP)

Passive multifrequency microwave sensors frequently struggle with difficulties of nonuniform spatial resolution among multiple channels. The raw measurements in the land-sea transition zone are seriously contaminated. Conventional analytical deconvolution techniques suffer from the tradeoff between spatial resolution enhancement and noise...

Systematic errors observed in CryoSat-2 elevation swaths on mountain glaciers and their implications

Our awareness of ice caps' and mountain glaciers' sensitivity to climate change has driven major advances in the application of remote sensing techniques during the past decade. Regarding ESA's SARIn altimeter CryoSat-2, processing the full waveform to generate swaths of elevation estimates has become standard practice in regions of complex...

Measuring Image Resolution in Ultrasound Localization Microscopy

The resolution of an imaging system is usually determined by the width of its point spread function and is measured using the Rayleigh criterion. For most system, it is in the order of the imaging wavelength. However, super resolution techniques such as localization microscopy in optical and ultrasound imaging can resolve features an order of...

A cutting edge 6U CubeSat ADCS design for Earth observation with sub-meter spatial resolution at 230–380 km altitude

A 6U CubeSat for Earth observation in 230–350 km orbits with sub-meter resolution is presented. The proposed Stable and Highly Accurate Pointing Earth-Imager (SHAPE) system’s attitude determination and control system (ADCS) is composed of a single momentum bias wheel with magnetic bearings at rotational speeds of 6000–7000 rpm and refined...

Spatial versus angular resolution for tractography-assisted planning of deep brain stimulation

Given the restricted total scanning time for clinical neuroimaging, it is unclear whether clinical diffusion MRI protocols would benefit more from higher spatial resolution or higher angular resolution. In this work, we investigated the relative benefit of improving spatial or angular resolution in diffusion MRI to separate two parallel...

Separating Geophysical Signals Using GRACE and High-Resolution Data: A Case Study in Antarctica

To fully exploit data from the Gravity Recovery and Climate Experiment (GRACE), we separate geophysical signals observed by GRACE in Antarctica by deriving high-spatial resolution maps for present-day glacial isostatic adjustment (GIA) and ice-mass changes with the least possible noise level. For this, we simultaneously (i) improve the...

PIV uncertainty propagation

This paper discusses the propagation of the instantaneous uncertainty of PIV measurements to statistical and instantaneous quantities of interest derived from the velocity field. The expression of the uncertainty of vorticity, velocity divergence, mean value and Reynolds stresses is derived. It is shown that the uncertainty of vorticity and...

Adaptive image interrogation for PIV: Application to compressible flows and interfaces

As an experimental tool, Particle Image Velocimetry has quickly superseded traditional point-wise measurements. The inherent image processing has become standardized though the performances are strongly dependent on user experience. Moreover, the arduously selected image interrogation parameters are applied uniformly throughout the image...

An adaptive sampling and windowing interrogation method in PIV

'Meuse Model Moulding': On the effect of spatial resolution

The main objective of this research is the determination of the effect of spatial resolution on hydrological model performance. In order to do so, a model of the Meuse basin was setup at the appropriate scales of Booij (2001) in the existing HBV structure and compared with a model of lower resolution (HBV-15). This comparison was made in three...