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Scholtes, Mathilde (author)Introduction: The positioning of spinal cord stimulation (SCS) leads in the epidural space to deliver therapy for chronic pain currently relies on intraoperative feedback from the patient. This feedback is not always reliable due to sedation, discomfort, and prone positioning of the patient. Excluding the need for patient feedback by performing...master thesis 2023
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Rice, Samantha (author)Numerous advancements have been made in transparent electrode technologies that can complement optogenetics and imaging modalities. However, several obstacles restrict the design and material of electrode devices, including the required flexibility, transparency, low impedance, high charge storage<br/>capacity (CSC), and high charge injection...master thesis 2023
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Reinders, Laurien (author)<b>Introduction</b>: Spinal Cord Stimulation (SCS) is a successful last-resort treatment for chronic pain patients, although its exact mechanisms of action (MOAs) still need to be unraveled. The MOAs of SCS partly rely on spinal mechanisms (gate control theory) and supraspinal mechanisms likely play a role as well. Pain processing involves a...master thesis 2022
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van Lange, Eline (author)Background: Complex regional pain syndrome (CRPS) is a clinical disorder characterized by continuous, disproportionate pain and sensory, vasomotor, sudomotor and motor trophic changes. CRPS patients have a heterogeneous clinical picture caused by multiple underlying pathophysiology mechanisms including inflammation, vasomotor disturbances and...master thesis 2022
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Schreuder, Anniek (author)Over the years, the marine contracting sector has faced many challenges surrounding safety, the economic fluctuations because of the oil crisis and now tackling the sustainability challenge. Years of experience in the offshore industry, a heavy industry that contributes significantly to the climate crisis through its environmental impact, is...master thesis 2022
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Teurlings, Jorn (author), Broek, Kees (author), Zuidema, Bart (author)Several studies have illustrated that Transcutaneous Vagus Nerve Stimulation (t-VNS) is an effective method for epileptic treatment. In contrast to the classical invasive Vagus Nerve Stimulation (VNS) which is already a Food and Drug Administration (FDA) approved therapy for epileptic treatment, t-VNS does not require surgical intervention....bachelor thesis 2022
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Chinchilla Perez, Marina (author)This project respond to the goal of an existing company to design an improved version of a pinpoint erotic product. This type of very targeted stimulation gives the opportunity to many FBP to explore their preferred hotspots, get to know themselves better and enrich their masturbation process. Apart from the fact that the stimulation of these...master thesis 2022
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Kluba, M.M. (author)The progress in the field of neurostimulation is impressive, both from a technical as well as from a therapeutic point of view. Nowadays, the electrical stimulation of the nervous system can be used to induce or suppress muscle responses. Additionally, it can also influence hearing, vision, immune system response, pain perception, and even...doctoral thesis 2022
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van den Berg, Boudewijn (author), Manoochehri, M. (author), Schouten, A.C. (author), van der Helm, F.C.T. (author), Buitenweg, Jan R. (author)Recent studies have established the presence of nociceptive steady-state evoked potentials (SSEPs), generated in response to thermal or intra-epidermal electric stimuli. This study explores cortical sources and generation mechanisms of nociceptive SSEPs in response to intra-epidermal electric stimuli. Our method was to stimulate healthy...journal article 2022
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Bauer, Staf (author), van Wingerden, Nathalie (author), Jacobs, Thomas (author), van der Horst, Annabel (author), Zhai, Peipei (author), Betting, Jan Harm L.F. (author), Strydis, C. (author), White, Joshua J. (author), De Zeeuw, Chris I. (author), Romano, Vincenzo (author)Neural activity exhibits oscillations, bursts, and resonance, enhancing responsiveness at preferential frequencies. For example, theta-frequency bursting and resonance in granule cells facilitate synaptic transmission and plasticity mechanisms at the input stage of the cerebellar cortex. However, whether theta-frequency bursting of Purkinje...journal article 2022
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Varkevisser, F. (author), Rashidi, A. (author), Lopes Marta da Costa, T.M. (author), Giagka, Vasiliki (author), Serdijn, W.A. (author)This work proposes a guideline for designing more energy-efficient electrical stimulators by analyzing the frequency spectrum of the stimuli. It is shown that the natural low-pass characteristic of the neuron’s membrane limits the energy transfer efficiency from the stimulator to the cell. Thus, to improve the transfer efficiency, it is proposed...conference paper 2022
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Rivandi, H. (author), Ghosh, Ishaan (author), Lopes Marta da Costa, T.M. (author)New non-imaging ultrasound applications, such as ultrasound stimulation and ultrasonic power transfer, need sub-millimeter volumetric spatial resolution, electronically control of the focal spot location, high ultrasound intensity, and a tiny form factor. Satisfying these requirements demands a high-frequency phased array ultrasound transducer....conference paper 2022
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Coolen, R.J.J. (author), Emmer, K.M. (author), Spantidea, P.I. (author), Asselt, E. van (author), Scheepe, J.R. (author), Serdijn, W.A. (author), Blok, B.F.M. (author)The first two objectives were to establish which stimulation parameters of kilohertz frequency alternating current (KHFAC) neuromodulation influence the effectiveness of pudendal nerve block and its safety. The third aim was to determine whether KHFAC neuromodulation of the pudendal nerve can relax the pelvic musculature, including the anal...journal article 2022
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Yukihara, Eduardo G. (author), bos, A.J.J. (author), Bilski, Paweł (author), McKeever, Stephen W.S. (author)The quest for new materials for thermoluminescence (TL) and optically stimulated luminescence (OSL) dosimetry continues to be a central line of research in luminescence dosimetry, occupying many groups and investigators, and is the topic of many publications. Nevertheless, it has also been a research area with many pitfalls, slow advances in...journal article 2022
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French, P.J. (author), Lawand, N. (author), Miralles, A. (author)Cochlear implants restore hearing to many people around the world. These devices are hand-made and have limitations in terms of sound quality. The maximum number of electrodes at present is 22 and this means that the sound spectrum is divided into 22 blocks. Furthermore, the breadth of the implant limits penetration and thus lower frequencies...conference paper 2022
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Andrew, Philippa Kate (author), Raudsepp, Allan (author), Nock, Volker (author), Fan, D. (author), Williams, Martin A.K. (author), Staufer, U. (author), Avci, Ebubekir (author)Optical micromachines have the potential to improve the capabilities of optical tweezers by amplifying forces and allowing for indirect handling and probing of specimens. However, systematic design and testing of micromachine performance is still an emerging field. In this work we have designed and tested an unsupported microlever, suitable for...conference paper 2022
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Hulleman, C.N. (author)<i>Localization microscopy has circumvented the diffraction limit by sequentially</i> imaging individual light emitting molecules at a time. The position of these individual molecules can be determined and a super-resolution reconstruction is made with improved resolution. Normally freely rotating emitters are used such that the point spread...doctoral thesis 2021
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Urso, A. (author)This thesis focus on improving the power efficiency of DC-DC converters for two different applications. In the field of implantable medical devices, electrical stimulation has been used as an established treatment for several diseases. It aims to deliver a well-defined amount of charge to the tissue in order to build up a specific electric field...doctoral thesis 2021
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Wymenga, Luutzen (author)Heart Failure (HF) is a disease of high mortality and morbidity with huge impact on health care systems worldwide. HF is a result of decreased contraction of the heart muscle. Current treatments focus on symptoms,and only a minor portion of HF patients is eligible for surgery. Assistance devices for cardiac contractionare currently only...master thesis 2021
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Brash, Rohan (author)Implantable epiretinal prostheses aim to restore visual capability for patients suffering from diseases such as Macular Degeneration and Retinitis Pigmentosa by bypassing damaged photoreceptors and electrically exciting Retinal Ganglion Cells (RGCs) directly. Next-generation devices will require single-cell resolution, and bidirectional...master thesis 2021