- document
-
Koele, Berend (author)Vagus nerve stimulation (VNS) has been proven to be an effective treatment for patients suffering from drug-resistant epilepsy. Current vagus nerve stimulators are either implantable devices or bulky, handheld devices. The implant consists of a pulse generator beneath the skin of the chest, connected to electrodes that are wired to the cervical...master thesis 2021
- document
-
Verzijl, Hubald (author)<i>Neuropathic pain</i> (NP) affects approximately seven to ten percent of the general population. Seventeen percent of NP patients scored their life as “worse than death”. A myriad of causes may underlie NP, such as stroke or spinal cord injury. Also, damage or disease of the <i>peripheral nervous system</i> (PNS) may result in NP. One of the...master thesis 2021
- document
-
Ottenheym, Lucas (author)Background: Spinal cord stimulation (SCS) is a last resort therapy for chronic pain syndromes, of which the exact mechanisms of action remain unknown. Although often effective, not all patients have sufficient pain reduction after implantation. Objective: Analyse the acute effects of tonic and burst SCS on spectral features in the whole brain...master thesis 2021
- document
-
Imanian Ghazanlou, Siavash (author), Eghbali, Baitallah (author), Petrov, R.H. (author)The effects of the post-deformation annealing on the microstructural evolution of hot rolled Al7075 matrix composites reinforced with CNTs and GNPs were investigated. The multi-pass hot rolling was applied on the stir cast samples. Annealing was then applied to the composites at 450 °C for 4 h. Microstructural evolution was examined by SEM,...journal article 2021
- document
-
van den Berg, Boudewijn (author), Manoochehri, M. (author), Kasting, Mindy (author), Schouten, A.C. (author), van der Helm, F.C.T. (author), Buitenweg, Jan R. (author)A sustained sensory stimulus with a periodic variation of intensity creates an electrophysiological brain response at associated frequencies, referred to as the steady-state evoked potential (SSEP). The SSEPs elicited by the periodic stimulation of nociceptors in the skin may represent activity of a brain network that is primarily involved in...journal article 2021
- document
-
Varkevisser, Francesc (author)Development of a visual prosthesis has the potential to help millions of patients with visual impairment around the world. One approach of visual prostheses is intracortical stimulation, where electrodes penetrating the visual cortex are used to create small light dots in the patients visual field. Said therapy requires an implantable...master thesis 2020
- document
-
Barbon-Pedrina, Alessandro (author)Approximately 15-20% of theworld population is aected by tinnitus, a hearing condition associated with phantomsound perception. A large number of suerers experience a severe level of tinnitus and they are not ableto conduct a normal life because they develop insomnia, depression, and distress.Extensive research has been made to study its...master thesis 2020
- document
-
Gökhan, Funda (author)Contractors can be stimulated to offer sustainable product innovations through tenders in the GWW sector. But despite the sustainability ambitions of clients to achieve a 100% circular economy by 2050 and sustainably generated energy in the Netherlands, contractors are hindered from being able to offer sustainable product innovations by clients....master thesis 2020
- document
-
Velea, A. (author), Vollebregt, S. (author), Hosman, T.B. (author), Pak, A. (author), Giagka, Vasiliki (author)This work aims to develop a smart neural interface with transparent electrodes to allow for electrical monitoring of the site of interest during optogenetic stimulation of the spinal cord. In this paper, a microfabrication process for the wafer-level development of such a compact, active, transparent and flexible implant is presented. Graphene...conference paper 2020
- document
-
Diakou, Androniki (author)The overarching goal of Engineered Heart Tissues (EHTs) is to develop functional 3D heart tissues in vitro with the potential to find drug targets, identify drug toxicity and predict the effects of the drugs in the body. This 3D model of the cardiac tissue consists of a bunch of cells, self-assembled around specific anchoring points the main aim...master thesis 2020
- document
-
Zufiria Gerbolés, Pedro (author)Neurostimulation is a common medical treatment modality used to treat neurological disorders. It applies electrical pulses to revert and prevent undesired neural behavior or to create desired neural behavior. The required specificity of said stimulation treatments is oftentimes achieved by implanting the neurostimulator close to the target area....master thesis 2020
- document
-
Broshuis, Lauren (author)We can all relate to the experience of wanting to shut of all the environmental stimuli around us, as our brain is overwhelmed and overstimulated by it all. Our surrounding environments can be improved if architects and designers learn more about how multi-sensory stimuli can enrich our perception of space, and when these triggers can take a...master thesis 2020
- document
-
Liebrand, Luka C. (author), van Wingen, Guido A. (author), Vos, F.M. (author), Denys, Damiaan (author), Caan, Matthan W.A. (author)Given the restricted total scanning time for clinical neuroimaging, it is unclear whether clinical diffusion MRI protocols would benefit more from higher spatial resolution or higher angular resolution. In this work, we investigated the relative benefit of improving spatial or angular resolution in diffusion MRI to separate two parallel...journal article 2020
- document
-
Mozaffarzadeh, M. (author), Minonzio, C.G. (author), de Jong, N. (author), Verweij, M.D. (author), Hemm, Simone (author), Daeichin, V. (author)Phase aberration in transcranial ultrasound imaging (TUI) caused by the human skull leads to an inaccurate image reconstruction. In this article, we present a novel method for estimating the speed of sound and an adaptive beamforming technique for phase aberration correction in a flat polyvinylchloride (PVC) slab as a model for the human...journal article 2020
- document
-
Lepillier, B.P. (author), Yoshioka, Keita (author), Parisio, Francesco (author), Bakker, R.R. (author), Bruhn, D.F. (author)In every tight formation reservoir, natural fractures play an important role for mass and energy transport and stress distribution. Enhanced Geothermal Systems (EGS) make no exception, and stimulation aims at increasing the reservoir permeability to enhance fluid circulation and heat transport. EGS development relies upon the complex task of...journal article 2020
- document
-
Bakker, Thomas (author)This research provide a proof of principle to use a sweat sensor system for real-time monitoring of medicine effectiveness in Cystic Fibrosis (CF) patients. CF is an autosomal recessive genetic disorder affecting mostly the respiratory, digestive and perspiration system. Patients with CF have dysfunctional chloride channels in their cells, due...master thesis 2019
- document
-
Lekkas, Konstantinos (author)Transcranial direct current stimulation (tDCS) is a noninvasive technique, allowing for the reversible modulation of activity in particular brain regions. TDCS has obtained much scientific interest and it promises many potential benefits to the patients.<br/><br/>However, tDCS that is performed today is almost the same with the method that was...master thesis 2019
- document
-
Stortelder, Roel (author)Analyzing the different signaling pathways of cells is key in understanding the basic functions of the cells in all organic systems from algae to humans. Not only do they help solve our questions on how organisms function, they also allow for new cures to be explored. A large variety of these signaling pathways can be influenced by light and can...master thesis 2019
- document
-
Emmer, Koen (author)A major cause for voiding dysfunction is the inability to relax the urethral sphincter. KiloHertz Frequency Alternating Current (KHFAC) stimulation can block signals that are travelling through the body; applying this type of stimulation at the pudendal nerve could inhibit the pulses that lead to contraction of the urethral sphincter, and...master thesis 2019
- document
-
Desmet, P.M.A. (author), Xue, H. (author), Fokkinga, S.F. (author)How people think and act is influenced by their transient mood state. Different moods stimulate different (thought/action) tendencies, such as the tendency to be attentive (when cheerful), to be cautious (whenanxious), or to be impatient (when agitated). To support an understandingof how mood can inform user-centered design, this paper reports...journal article 2019